1. EDITORIAL

   • H. Höfler
   • A. K. Raap

   EDITORIAL Pages: 289 - 289

2. Multi-colour brightfield in situ hybridisation on tissue sections

   • A. H. N. Hopman
   • Sandra Claessen
   • Ernst J. M. Speel

   ORIGINAL PAPER Pages: 291 - 298

3. Spectral karyotyping, a 24-colour FISH technique for the identification of chromosomal rearrangements

   • Merryn Macville
   • T. Veldman
   • T. Ried

   ORIGINAL PAPER Pages: 299 - 305

4. Simultaneous triple fluorescence detection of mRNA localization, nuclear DNA, and apoptosis in cultured cells using confocal scanning laser microscopy

   • Wendell P. Davis
   • Yvonne M. W. Janssen
   • D. J. Taatjes

   ORIGINAL PAPER Pages: 307 - 311

5. Signal amplification at the ultrastructural level using biotinylated tyramides and immunogold detection

   • C. Schöfer
   • Klara Weipoltshammer
   • Franz Wachtler

   ORIGINAL PAPER Pages: 313 - 319

6. High sensitivity detection of HPV-16 in SiHa and CaSki cells utilizing FISH enhanced by TSA

   • Karl Adler
   • Thomas Erickson
   • M. Bobrow

   ORIGINAL PAPER Pages: 321 - 324

7. Target and signal amplification: approaches to increase the sensitivity of in situ hybridization

   • P. Komminoth
   • Martin Werner

   REVIEW Pages: 325 - 333

8. Non-radioactive in situ hybridization for mRNA with emphasis on the use of oligodeoxynucleotide probes

   • D. M. Hougaard
   • Henrik Hansen
   • Lars-Inge Larsson

   REVIEW Pages: 335 - 344

9. Subcellular localization of specific mRNAs and their protein products in Purkinje cells by combined fluorescence in situ hybridization and immunocytochemistry

   • I. Wanner
   • Stephan L. Baader
   • K. Schilling

   ORIGINAL PAPER Pages: 345 - 357

10. Oestradiol, a new hapten for detecting nucleic acid sequences by FISH

    • Mariëtte P. C. van de Corput
    • Roeland W. Dirks
    • A. K. Raap

    ORIGINAL PAPER Pages: 359 - 364

11. The U22 host gene (UHG): chromosomal localization of UHG and distribution of U22 small nucleolar RNA

    • Mark R. Frey
    • W. Wu
    • A. G. Matera

    ORIGINAL PAPER Pages: 365 - 370

12. Detection of mRNAs encoding peroxisomal proteins by non-radioactive in situ hybridization with digoxigenin-labelled cRNAs

    • E. Baumgart
    • Arno Schad
    • H. Dariush Fahimi

    REVIEW Pages: 371 - 379

13. Interphase cytogenetics in pathology: principles, methods, and applications of fluorescence in situ hybridization (FISH)

    • M. Werner
    • L. Wilkens
    • Paul Komminoth

    REVIEW Pages: 381 - 390

14. Fluorescence in situ hybridization as a diagnostic tool in malignant lymphomas

    • R. Siebert
    • Klaus Weber-Matthiesen

    ORIGINAL PAPER Pages: 391 - 402

15. Comparative genomic hybridisation for the analysis of chromosomal imbalances in solid tumours and haematological malignancies

    • H. Zitzelsberger
    • Lars Lehmann
    • Manfred Bauchinger

    REVIEW Pages: 403 - 417

16. Interphase cytogenetics and comparative genomic hybridization of human epithelial cancers and precursor lesions

    • H. van Dekken
    • Carla Rosenberg
    • Janneke C. Alers

    ORIGINAL PAPER Pages: 419 - 430

17. Self-sustained sequence replication (3SR): an alternative to PCR

    • J. D. Mueller
    • Barbara Pütz
    • Heinz Höfler

    ORIGINAL PAPER Pages: 431 - 437

18. Single- and double-color oligonucleotide primed in situ labeling (PRINS): applications in pathology

    • Ludwig Wilkens
    • Joelle Tchinda
    • M. Werner

    ORIGINAL PAPER Pages: 439 - 446

19. Laser-assisted preparation of single cells from stained histological slides for gene analysis

    • I. Becker
    • Karl-Friedrich Becker
    • Heinz Höfler

    ORIGINAL PAPER Pages: 447 - 451