1. Introduction

   • Massimo Pandolfo

   OriginalPaper Pages: 1 - 2

2. Friedreich ataxia: The clinical picture

   • Massimo Pandolfo

   OriginalPaper Pages: 3 - 8

3. The pathogenesis of Friedreich ataxia and the structure and function of frataxin

   • Massimo Pandolfo
   • Annalisa Pastore

   OriginalPaper Pages: 9 - 17

4. Multicellular models of Friedreich ataxia

   • Hélène Puccio

   OriginalPaper Pages: 18 - 24

5. Idebenone: An emerging therapy for Friedreich ataxia

   • Thomas Meier
   • Gunnar Buyse

   OriginalPaper Pages: 25 - 30

6. Pharmacokinetic properties and metabolism of idebenone

   • Klaus Kutz
   • Jürgen Drewe
   • Pierre Vankan

   OriginalPaper Pages: 31 - 35

7. Evaluating the progression of Friedreich ataxia and its treatment

   • Martin B. Delatycki

   OriginalPaper Pages: 36 - 41

8. Clinical experience with high-dose idebenone in Friedreich ataxia

   • Jörg B. Schulz
   • Nicholas A. Di Prospero
   • Kenneth Fischbeck

   OriginalPaper Pages: 42 - 45

9. Idebenone in the Treatment of Friedreich Ataxia

   AUTHORS’ BIOGRAPHIES Pages: 46 - 48