1. Acknowledgement to Referees

   ACKNOWLEDGEMENT TO REFEREES Open access 15 November 2021 Pages: 427 - 430

2. Associations Between Anticholinergic Medication Exposure and Adverse Health Outcomes in Older People with Frailty: A Systematic Review and Meta-analysis

   • David Mehdizadeh
   • Matthew Hale
   • Andrew Clegg

   Systematic Review Open access 23 June 2021 Pages: 431 - 458

   

3. Current Status, Challenges, and Future Perspectives of Real-World Data and Real-World Evidence in Japan

   • Katsutoshi Hiramatsu
   • Annabel Barrett
   • PhRMA Japan Medical Affairs Committee Working Group 1

   Review Article Open access 19 June 2021 Pages: 459 - 480

   

4. Stroke Risk Among Non-Elderly Users of Haloperidol or First-Generation Antipsychotics vs Second-Generation Antipsychotics: A Cohort Study from a US Health Insurance Claims Database

   • Daniel Fife
   • Clair Blacketer
   • James Weaver

   Original Research Article Open access 09 June 2021 Pages: 481 - 496

   

5. Retrospective Claims Analysis of Treatment Patterns, Relapse, Utilization, and Cost Among Patients with Multiple Sclerosis Initiating Second-Line Disease-Modifying Therapy

   • Leorah Freeman
   • Arianna Kee
   • Rina Mehta

   Original Research Article Open access 16 June 2021 Pages: 497 - 508

   

6. Real-World Clinical Use and Outcomes of Telavancin for the Treatment of Bone and Joint Infections: Results from the Telavancin Observational Use Registry (TOUR™)

   • Charles R. Sims
   • Adam M. Bressler
   • Bibiana Castaneda-Ruiz

   Original Research Article Open access 26 May 2021 Pages: 509 - 518

   

7. Potentially Inappropriate Medication Use in Older Adults with Alzheimer’s Disease and Related Dementias Living in the Community: A Cross-Sectional Analysis

   • Lauren E. Vickers
   • Ashley I. Martinez
   • Daniela C. Moga

   Original Research Article Open access 10 June 2021 Pages: 519 - 526

   

8. Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Real Life: One-Year Clinical and Economic Outcomes

   • Romain Giraud
   • Nicolas Delmotte
   • Manon Roche

   Original Research Article Open access 25 June 2021 Pages: 527 - 535

   

9. European and US Real-World Treatment Patterns in Patients with Epidermal Growth Factor Receptor Mutation-Positive Non-Small Cell Lung Cancer: A Retrospective Medical Record Review

   • Riyaz Shah
   • Nicolas Girard
   • Josephine Feliciano

   Original Research Article Open access 17 September 2021 Pages: 537 - 545

   

10. Risk of Bleeding Associated with Antidepressant Drugs: The Competitive Impact of Antithrombotics in Quantitative Signal Detection

    • René Zeiss
    • Christoph Hiemke
    • Maximilian Gahr

    Original Research Article Open access 11 June 2021 Pages: 547 - 554

11. Factors Associated with Hyponatremia in Patients Newly Prescribed Citalopram: A Retrospective Observational Study

    • Andrea Christine Shysh
    • Zahinoor Ismail
    • Christopher Naugler

    Original Research Article Open access 23 May 2021 Pages: 555 - 563

    

12. Real-World Persistence, Maintenance Dosing, and Pre-Post Corticosteroid and Opioid Use Among Crohn’s Disease Patients with Prescription Claims for Ustekinumab in the USA

    • Zhijie Ding
    • Camilo Obando
    • Terra Slaton

    Original Research Article Open access 16 June 2021 Pages: 565 - 575

    

13. Comparison Between Health Insurance Claims and Electronic Health Records (EHRs) for Metastatic Non-small-cell Lung Cancer (NSCLC) Patient Characteristics and Treatment Patterns: A Retrospective Cohort Study

    • Yookyung Christy Choi
    • Dongmu Zhang
    • Jerzy E. Tyczynski

    Original Research Article Open access 28 August 2021 Pages: 577 - 587

    

14. Safety of Anthroposophic Medicinal Products: An Analysis of Adverse Drug Reactions from German Pharmacovigilance Databases

    • Miek C. Jong
    • Herman van Wietmarschen
    • Harald J. Hamre

    Original Research Article Open access 28 July 2021 Pages: 589 - 601

    

15. Anticoagulation in Very Old Patients with Atrial Fibrillation (AVOPA): A Descriptive Observational Study

    • Maximilian Hupfer
    • Markus Gosch

    Original Research Article Open access 11 June 2021 Pages: 603 - 614