1. New-format package inserts soon to be rolled out in Japan

   News item 23 February 2019 Pages: 1 - 1

2. US FDA issues final guidance for issuing public warnings/notices

   Comment 23 February 2019 Pages: 2 - 2

3. US pilot programme targets security of drug supply chain

   News item 23 February 2019 Pages: 3 - 3

4. 'Z drugs' linked with abuse, dependence, withdrawal in EU

   Review 23 February 2019 Pages: 4 - 4

5. Adverse event outcome reporting in systematic reviews

   Clinical study 23 February 2019 Pages: 5 - 5

6. Age-related haematological toxicity with docetaxel

   Clinical study 23 February 2019 Pages: 6 - 6

7. Bleeding after adding antiplatelet drugs to DOACs

   Clinical study 23 February 2019 Pages: 7 - 7

8. Free text description of ADRs preferred to patient-friendly list

   Clinical study 23 February 2019 Pages: 8 - 8

9. Immediate-postpartum DMPA therapy increases VTE risk

   Clinical study 23 February 2019 Pages: 9 - 9

10. Improved ADR detection with machine-learning model

    Non-clinical study 23 February 2019 Pages: 10 - 10

11. Isoniazid can cause hepatotoxicity in paediatrics taking nevirapine

    Clinical study 23 February 2019 Pages: 11 - 11

12. Serious psychiatric treatment failure with aripiprazole?

    Clinical study 23 February 2019 Pages: 12 - 12

13. Abacavir

    Case report 23 February 2019 Pages: 13 - 13

14. Adalimumab

    Case report 23 February 2019 Pages: 14 - 14

15. Adalimumab/etanercept

    Case report 23 February 2019 Pages: 15 - 15

16. Afatinib/gefitinib/osimertinib

    Case report 23 February 2019 Pages: 16 - 16

17. Alcohol/tacrolimus interaction

    Case report 23 February 2019 Pages: 17 - 17

18. Alemtuzumab

    Case report 23 February 2019 Pages: 18 - 18

19. Alemtuzumab

    Case report 23 February 2019 Pages: 19 - 19

20. Alendronic acid

    Case report 23 February 2019 Pages: 20 - 20

21. Alendronic acid/risedronic acid/zoledronic acid

    Case report 23 February 2019 Pages: 21 - 21

22. Allopurinol

    Case report 23 February 2019 Pages: 22 - 22

23. Amikacin/ceftazidime/oxacillin

    Case report 23 February 2019 Pages: 23 - 23

24. Amikacin/ethambutol

    Case report 23 February 2019 Pages: 24 - 24

25. Amiodarone

    Case report 23 February 2019 Pages: 25 - 25

26. Amphotericin B/amphotericin B liposomal

    Case report 23 February 2019 Pages: 26 - 26

27. Amphotericin-b/voriconazole

    Case report 23 February 2019 Pages: 27 - 27

28. Anthracyclines/cyclophosphamide/etoposide

    Case report 23 February 2019 Pages: 28 - 28

29. Antibacterials

    Case report 23 February 2019 Pages: 29 - 29

30. Antibacterials/pramocaine

    Case report 23 February 2019 Pages: 30 - 30

31. Antibiotics

    Case report 23 February 2019 Pages: 31 - 31

32. Anticoagulants/antiplatelets/factor-VIII inhibitor bypassing fraction

    Case report 23 February 2019 Pages: 32 - 33

33. Antihyperglycaemics/antineoplastics

    Case report 23 February 2019 Pages: 33 - 33

34. Antineoplastics

    Case report 23 February 2019 Pages: 34 - 34

35. Antineoplastics

    Case report 23 February 2019 Pages: 35 - 35

36. Antineoplastics/fluconazole/hydrocortisone

    Case report 23 February 2019 Pages: 36 - 36

37. Antineoplastics/ibrutinib

    Case report 23 February 2019 Pages: 37 - 37

38. Antipsychiatrics

    Case report 23 February 2019 Pages: 38 - 38

39. Antipsychotics/maprotiline/metoclopramide

    Case report 23 February 2019 Pages: 39 - 39

40. Antiretrovirals

    Case report 23 February 2019 Pages: 40 - 40

41. Antithymocyte-globulin/ciclosporin

    Case report 23 February 2019 Pages: 41 - 41

42. Antituberculars

    Case report 23 February 2019 Pages: 42 - 42

43. Antituberculars

    Case report 23 February 2019 Pages: 43 - 43

44. Apixaban/dabigatran etexilate

    Case report 23 February 2019 Pages: 44 - 44

45. Aspirin/ticagrelor

    Case report 23 February 2019 Pages: 45 - 45

46. Atorvastatin/colchicine

    Case report 23 February 2019 Pages: 46 - 46

47. Atorvastatin/ticagrelor interaction

    Case report 23 February 2019 Pages: 47 - 47

48. Atropine/pentazocine/promethazine

    Case report 23 February 2019 Pages: 48 - 48

49. Axitinib

    Case report 23 February 2019 Pages: 49 - 49

50. Azathioprine

    Case report 23 February 2019 Pages: 50 - 50