1. Changes to phase IIb Pivanex trial due to safety concerns

   Media release 21 January 2013 Pages: 2 - 2

2. Increased number of ED visits associated with benzodiazepine abuse

   Media release 21 January 2013 Pages: 2 - 2

3. Increased risk of thromboembolic events with Avastin

   News item 21 January 2013 Pages: 2 - 2

4. Kavain: safety evidence to be reviewed

   News item 21 January 2013 Pages: 2 - 2

5. News from Singapore: serious skin reactions

   News item 21 January 2013 Pages: 2 - 2

6. Update on the Office of Drug Safety at the US FDA

   Meeting report 21 January 2013 Pages: 3 - 4

7. Voluntary reporting of medical errors needs to be anonymous

   News item 21 January 2013 Pages: 4 - 4

8. β-adrenoceptor agonists increase cardiovascular risk

   Incidence study 21 January 2013 Pages: 5 - 5

9. Adverse events in 2.2% of hospital episodes

   News item 21 January 2013 Pages: 5 - 5

10. Inhaled corticosteroids: no increase in fracture risk

    Clinical study 21 January 2013 Pages: 5 - 5

11. Proton pump inhibitors increase risk of Clostridium infection

    News item 21 January 2013 Pages: 5 - 5

12. Amifostine

    Case report 21 January 2013 Pages: 6 - 6

13. Antithymocyte globulin interaction

    Case report 21 January 2013 Pages: 6 - 6

14. Azathioprine interaction

    Case report 21 January 2013 Pages: 6 - 7

15. Cisplatin

    Case report 21 January 2013 Pages: 7 - 7

16. Dimethyl sulfoxide

    Case report 21 January 2013 Pages: 7 - 7

17. Enalapril

    Case report 21 January 2013 Pages: 7 - 7

18. Esomeprazole

    Case report 21 January 2013 Pages: 7 - 8

19. Fluorouracil/folinic acid/irinotecan

    Case report 21 January 2013 Pages: 8 - 8

20. Fluoxetine/fluvoxamine/paroxetine

    Case reports 21 January 2013 Pages: 8 - 8

21. Gefitinib

    Case report 21 January 2013 Pages: 9 - 9

22. Ifosfamide

    Case reports 21 January 2013 Pages: 9 - 9

23. Imatinib interaction

    Case report 21 January 2013 Pages: 9 - 9

24. Imipenem

    Case report 21 January 2013 Pages: 10 - 10

25. Interferon-α

    Case report 21 January 2013 Pages: 10 - 10

26. Lansoprazole interaction

    Case reports 21 January 2013 Pages: 10 - 10

27. Mercaptopurine overdose

    Case reports 21 January 2013 Pages: 10 - 10

28. Olanzapine

    Case report 21 January 2013 Pages: 10 - 11

29. Peginterferon-α-2a/peginterferon-α-2b/ribavirin

    Case reports 21 January 2013 Pages: 11 - 11

30. Radioiodine

    Case report 21 January 2013 Pages: 11 - 12

31. Risperidone

    Case report 21 January 2013 Pages: 12 - 12

32. Scopolamine hydrobromide

    Case report 21 January 2013 Pages: 12 - 12

33. Simvastatin interaction

    Case report 21 January 2013 Pages: 12 - 12

34. Sirolimus

    Case report 21 January 2013 Pages: 13 - 13

35. Sirolimus

    Case reports 21 January 2013 Pages: 13 - 13

36. Tacrolimus

    Case reports 21 January 2013 Pages: 13 - 14

37. Tramadol interaction

    Case report 21 January 2013 Pages: 14 - 14

38. Valproate semisodium

    Case report 21 January 2013 Pages: 14 - 14

39. Vancomycin

    Case report 21 January 2013 Pages: 14 - 14

40. Ziprasidone overdose

    Case report 21 January 2013 Pages: 14 - 15