1. ADR news from Health Canada

   News item 21 January 2013 Pages: 2 - 2

2. Pyrazinamide/rifampicin: not recommended for TB prophylaxis

   News item 21 January 2013 Pages: 2 - 2

3. Carboplatin: skin tests predictive of hypersensitivity?

   Clinical study 21 January 2013 Pages: 3 - 3

4. Corticosteroids: benefits of inhaled use outweigh any risks

   Review 21 January 2013 Pages: 3 - 3

5. Corticosteroids: no increase in fracture risk with inhaled or nasal use

   Incidence study 21 January 2013 Pages: 3 - 3

6. Decline in HRT use confirms physicians' rapid response

   Clinical study 21 January 2013 Pages: 3 - 3

7. HAART: discontinuation most frequently due to GI effects

   Clinical study 21 January 2013 Pages: 4 - 4

8. Hypericum and OCs may increase pregnancy risk

   Volunteers 21 January 2013 Pages: 4 - 4

9. Linezolid: no greater risk of thrombocytopenia than vancomycin

   Clinical study 21 January 2013 Pages: 4 - 4

10. Methylphenidate: small increases in BP and HR in children with ADHD

    Clinical study 21 January 2013 Pages: 4 - 4

11. Protease inhibitors: MI risk increases with duration of use

    Incidence study 21 January 2013 Pages: 4 - 4

12. α-blockers: increased hip/femur fracture risk in older men

    Clinical study 21 January 2013 Pages: 5 - 5

13. Antineoplastics: persistent impaired glucose metabolism in ALL

    Clinical study 21 January 2013 Pages: 5 - 5

14. HRT: long term use decreases risk of AMI

    Clinical study 21 January 2013 Pages: 5 - 5

15. Lamotrigine: may be relatively `safe' in pregnancy

    Clinical study 21 January 2013 Pages: 5 - 5

16. Antineoplastics

    Case reports 21 January 2013 Pages: 6 - 6

17. Antipsychotics

    Case report 21 January 2013 Pages: 6 - 6

18. Antituberculars

    Case report 21 January 2013 Pages: 7 - 7

19. Azathioprine/ciclosporin/prednisolone

    Case report 21 January 2013 Pages: 7 - 7

20. Bupropion

    Case report 21 January 2013 Pages: 7 - 7

21. Celecoxib

    Case report 21 January 2013 Pages: 8 - 8

22. Cetuximab

    Case reports 21 January 2013 Pages: 8 - 8

23. Chlorphenamine/dextromethorphan/paracetamol overdose

    Case reports 21 January 2013 Pages: 8 - 8

24. Clopidogrel

    Case report 21 January 2013 Pages: 8 - 8

25. Clozapine interaction

    Case reports 21 January 2013 Pages: 9 - 9

26. Estradiol

    Case report 21 January 2013 Pages: 9 - 9

27. Guanfacine

    Case report 21 January 2013 Pages: 9 - 9

28. Hydroxycarbamide

    Case report 21 January 2013 Pages: 9 - 10

29. Imatinib

    Case report 21 January 2013 Pages: 10 - 10

30. Imatinib

    Case report 21 January 2013 Pages: 10 - 10

31. Immunoglobulins

    Case reports 21 January 2013 Pages: 11 - 11

32. Infliximab

    Case report 21 January 2013 Pages: 11 - 11

33. Isopropyl alcohol abuse

    Case report 21 January 2013 Pages: 11 - 11

34. Itraconazole

    Case report 21 January 2013 Pages: 11 - 11

35. Mycophenolate mofetil

    Case report 21 January 2013 Pages: 11 - 11

36. Ketoconazole

    Case report 21 January 2013 Pages: 11 - 12

37. Nevirapine

    Case reports 21 January 2013 Pages: 12 - 12

38. Octreotide

    Case report 21 January 2013 Pages: 13 - 13

39. Olanzapine

    Case report 21 January 2013 Pages: 13 - 13

40. Quinine

    Case report 21 January 2013 Pages: 13 - 13

41. Rifampicin

    Case report 21 January 2013 Pages: 13 - 13

42. Risperidone

    Case reports 21 January 2013 Pages: 13 - 14

43. Risperidone

    Case report 21 January 2013 Pages: 14 - 14

44. Ropivacaine

    Case report 21 January 2013 Pages: 14 - 14

45. Smallpox vaccine

    Case report 21 January 2013 Pages: 14 - 14

46. Tosufloxacin

    Case report 21 January 2013 Pages: 14 - 15