1. ADR updates from Canada

   News item 18 January 2013 Pages: 2 - 2

2. ADR updates from Japan

   News item 18 January 2013 Pages: 2 - 2

3. New CHF therapies: safety vs quality of life

   Comment 18 January 2013 Pages: 2 - 2

4. Spontaneous ADR reporting in the spotlight

   Meeting report 18 January 2013 Pages: 3 - 4

5. A possible mechanism for the 18 deaths associated with sorivudine and fluorouracil prodrug coadministration

   Animal 18 January 2013 Pages: 4 - 4

6. Influenza vaccine `safe' in patients with egg allergy

   Clinical study 18 January 2013 Pages: 4 - 4

7. Withdrawal syndrome can occur with cyproterone

   Clinical study 18 January 2013 Pages: 4 - 4

8. High risk of thromboembolic events with cisplatin-based antineoplastic therapy

   Incidence study 18 January 2013 Pages: 5 - 5

9. Influenza vaccine does not significantly increase heart transplant rejection

   Clinical study 18 January 2013 Pages: 5 - 5

10. Menstruation disorders with local triamcinolone injection

    Incidence study 18 January 2013 Pages: 5 - 5

11. No adverse effects in children after in utero and neonatal zidovudine exposure

    Incidence study 18 January 2013 Pages: 5 - 5

12. Anorectic-induced valvular heart disease risk assessed

    Incidence study 18 January 2013 Pages: 6 - 6

13. Increased risk of CHF with > 950 mg/m2 epirubicin

    Incidence study 18 January 2013 Pages: 6 - 6

14. Low-dose OCs are `safe with respect to stroke'

    Incidence study 18 January 2013 Pages: 6 - 6

15. Major association between calcium antagonists and cancer unlikely

    Incidence study 18 January 2013 Pages: 6 - 6

16. Alprostadil

    Case report 18 January 2013 Pages: 7 - 7

17. Amphotericin B

    Case report 18 January 2013 Pages: 7 - 7

18. Clomifene/menotropins/triptorelin

    Case report 18 January 2013 Pages: 7 - 7

19. Cyclosporin

    Case report 18 January 2013 Pages: 7 - 7

20. Cyclosporin interaction

    Case reports 18 January 2013 Pages: 7 - 8

21. Cyclosporin interaction

    Case report 18 January 2013 Pages: 8 - 8

22. Fluorouracil

    Case report 18 January 2013 Pages: 8 - 8

23. Flutamide/leuprorelin

    Case report 18 January 2013 Pages: 8 - 8

24. Immunoglobulin

    Case report 18 January 2013 Pages: 8 - 8

25. Mefenamic acid

    Case report 18 January 2013 Pages: 8 - 9

26. Mefloquine

    Case report 18 January 2013 Pages: 9 - 9

27. Melphalan

    Case reports 18 January 2013 Pages: 9 - 9

28. Nicotinic acid

    Case reports 18 January 2013 Pages: 9 - 9

29. Nifedipine

    Case report 18 January 2013 Pages: 9 - 9

30. Nimesulide

    Case report 18 January 2013 Pages: 9 - 10

31. Praziquantel

    Case report 18 January 2013 Pages: 10 - 10

32. Prednisone

    Case report 18 January 2013 Pages: 10 - 10

33. Propylene glycol

    Case report 18 January 2013 Pages: 10 - 10

34. Risperidone

    Case report 18 January 2013 Pages: 10 - 10

35. Risperidone withdrawal

    Case report 18 January 2013 Pages: 11 - 11

36. Sertraline

    Case report 18 January 2013 Pages: 11 - 11

37. Tacrolimus

    Case report 18 January 2013 Pages: 12 - 12

38. Tamoxifen

    Case reports 18 January 2013 Pages: 12 - 12

39. Ticlopidine

    Case report 18 January 2013 Pages: 12 - 12

40. Troglitazone

    Case report 18 January 2013 Pages: 12 - 12

41. Valproic acid

    Case reports 18 January 2013 Pages: 12 - 12