1. Special warning to be added to methotrexate packaging

   News item 09 February 2019 Pages: 1 - 1

2. US FDA update on nitrosamine impurities investigation

   Comment 09 February 2019 Pages: 2 - 2

3. Draft US guidances issued to assess REMS programmes

   Comment 09 February 2019 Pages: 3 - 3

4. Account for voriconazole-induced hepatotoxicity early on

   Clinical study 09 February 2019 Pages: 4 - 4

5. ADR signal dictionary developed in Korea for PV purposes

   Non-clinical study 09 February 2019 Pages: 5 - 5

6. Anti-PD-1 antibodies: immune-related adverse events and efficacy

   Clinical study 09 February 2019 Pages: 6 - 6

7. Antidepressants, antipsychotics in paediatric patients vs adults

   Clinical study 09 February 2019 Pages: 7 - 7

8. Cutaneous reactions with old vs new antiepileptic drugs

   Clinical study 09 February 2019 Pages: 8 - 8

9. Febuxostat versus allopurinol: lower risk of skin disorders

   Clinical study 09 February 2019 Pages: 9 - 9

10. Models predict levetiracetam-related psychiatric adverse events

    Clinical study 09 February 2019 Pages: 10 - 10

11. More inappropriate prescribing with newer STOPP/START criteria

    Clinical study 09 February 2019 Pages: 11 - 11

12. Piroxicam-induced FDE and cross-reactivity to meloxicam

    Clinical study 09 February 2019 Pages: 12 - 12

13. Serious infections with tocilizumab in rheumatoid arthritis

    Clinical study 09 February 2019 Pages: 13 - 13

14. Abiraterone acetate

    Case report 09 February 2019 Pages: 14 - 14

15. Acitretin/isotretinoin

    Case report 09 February 2019 Pages: 15 - 15

16. Adalimumab

    Case report 09 February 2019 Pages: 16 - 16

17. Afatinib/cetuximab/erlotinib

    Case report 09 February 2019 Pages: 17 - 17

18. Alemtuzumab

    Case report 09 February 2019 Pages: 18 - 18

19. Alendronic-acid

    Case report 09 February 2019 Pages: 19 - 19

20. Allopurinol

    Case report 09 February 2019 Pages: 20 - 20

21. Allopurinol

    Case report 09 February 2019 Pages: 21 - 21

22. Allopurinol

    Case report 09 February 2019 Pages: 22 - 22

23. Alprostadil/heparin

    Case report 09 February 2019 Pages: 23 - 23

24. Alteplase

    Case report 09 February 2019 Pages: 24 - 24

25. Amoxicillin/ciclosporin/nimesulide

    Case report 09 February 2019 Pages: 25 - 25

26. Amphotericin B

    Case report 09 February 2019 Pages: 26 - 26

27. Amphotericin-B-liposomal/infliximab

    Case report 09 February 2019 Pages: 27 - 27

28. Amrubicin/etoposide/topotecan

    Case report 09 February 2019 Pages: 28 - 28

29. Analgesics/benzylpenicillin

    Case report 09 February 2019 Pages: 29 - 29

30. Antibacterial and antiepileptic drugs interaction

    Case report 09 February 2019 Pages: 30 - 30

31. Antibacterials

    Case report 09 February 2019 Pages: 31 - 31

32. Antibacterials/fluconazole

    Case report 09 February 2019 Pages: 32 - 32

33. Anticoagulants/antiplatelets

    Case report 09 February 2019 Pages: 33 - 33

34. Antihyperglycaemics

    Case report 09 February 2019 Pages: 34 - 34

35. Antihypertensives

    Case report 09 February 2019 Pages: 35 - 35

36. Antineoplastics

    Case report 09 February 2019 Pages: 36 - 36

37. Antineoplastics

    Case report 09 February 2019 Pages: 37 - 37

38. Antineoplastics

    Case report 09 February 2019 Pages: 38 - 38

39. Antineoplastics

    Case report 09 February 2019 Pages: 39 - 39

40. Antineoplastics

    Case report 09 February 2019 Pages: 40 - 40

41. Antiparkinsonians

    Case report 09 February 2019 Pages: 41 - 41

42. Antiretrovirals

    Case report 09 February 2019 Pages: 42 - 42

43. Antituberculars

    Case report 09 February 2019 Pages: 43 - 43

44. Antivirals

    Case report 09 February 2019 Pages: 44 - 44

45. Antivirals

    Case report 09 February 2019 Pages: 45 - 45

46. Apremilast

    Case report 09 February 2019 Pages: 46 - 46

47. Aripiprazole overdose

    Case report 09 February 2019 Pages: 47 - 47

48. Articaine/prilocaine/procaine

    Case report 09 February 2019 Pages: 48 - 48

49. Asparaginase

    Case report 09 February 2019 Pages: 49 - 49

50. Asparaginase

    Case report 09 February 2019 Pages: 50 - 50