Treatment of ovarian cancer beyond chemotherapy: Are we hitting the target? Álvaro Henrique Ingles GarcesMariane Sousa Fontes DiasAndréia Cristina de Melo Review Article 12 September 2014 Pages: 221 - 234
Prognostic relevance of carbonic anhydrase IX expression is distinct in various subtypes of breast cancer and its silencing suppresses self-renewal capacity of breast cancer cells Lāsma IvanovaElīna ZandbergaAija Linē Original Article 25 November 2014 Pages: 235 - 246
Intravenous 3-weekly paclitaxel and metronomic oral cyclophosphamide in patients with advanced urothelial cancer previously treated with gemcitabine and platinum Ji Hyun ParkJae-Lyun Lee Original Article 27 November 2014 Pages: 247 - 254
Preoperative neutrophil-to-lymphocyte ratio predicts response to first-line platinum-based chemotherapy and prognosis in serous ovarian cancer Ying WangPing LiuHong Ni Original Article 27 November 2014 Pages: 255 - 262
Antitumor efficacy of tangeretin by targeting the oxidative stress mediated on 7,12-dimethylbenz(a) anthracene-induced proliferative breast cancer in Sprague–Dawley rats Kuppusamy PeriyasamyKuppusamy BaskaranDhanapal Sakthisekaran Original Article 28 November 2014 Pages: 263 - 272
Pre-treatment serum total bilirubin level as an indicator of optimal CPT-11 dosage Katsuya MakiharaSayaka AzumaIzumi Nakata Original Article 29 November 2014 Pages: 273 - 279
Cellular uptake kinetics of bortezomib in relation to efficacy in myeloma cells and the influence of drug transporters Jannick ClemensAnja SeckingerJohanna Weiss Original Article 05 December 2014 Pages: 281 - 291
A multi-institution phase II study of gemcitabine/cisplatin/S-1 (GCS) combination chemotherapy for patients with advanced biliary tract cancer (KHBO 1002) Masashi KanaiEtsuro HatanoTatsuya Ioka Original Article 05 December 2014 Pages: 293 - 300
Efficacy of neo-adjuvant chemotherapy with TEC regimen on breast cancer Xi GuYang ZhangWen-Hai Zhang Original Article 06 December 2014 Pages: 301 - 308
A Phase I study of cabazitaxel in patients with advanced gastric cancer who have failed prior chemotherapy (GASTANA) Yoon-Koo KangBaek-Yeol RyooMin-Hee Ryu Original Article 09 December 2014 Pages: 309 - 318
Phase II trial of miniDOX (reduced dose docetaxel–oxaliplatin–capecitabine) in “suboptimal” patients with advanced gastric cancer (AGC). TTD 08-02 F. RiveraB. MassutíE. Aranda Original Article 10 December 2014 Pages: 319 - 324
Phase II study evaluating efficacy and safety of everolimus with letrozole for management of advanced (unresectable or metastatic) non-small cell lung cancer after failure of platinum-based treatment: a preliminary analysis of toxicity Nimit SinghalSina VatandoustMichael P. Brown Original Article 11 December 2014 Pages: 325 - 331
Pharmacokinetic/pharmacodynamic-based decision making in the development of MK-0888, a VEGFR-2/FLT-3 kinase inhibitor Marian IwamotoEvan J. FriedmanJohn A. Wagner Original Article 19 December 2014 Pages: 333 - 342
A Phase I/biomarker study of bevacizumab in combination with CNTO 95 in patients with advanced solid tumors Hope E. UronisJingquan JiaHerbert I. Hurwitz Original Article 20 December 2014 Pages: 343 - 352
Oxymatrine targets EGFRp-Tyr845 and inhibits EGFR-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells Bingyu GuoTingting ZhangXiaoming Li Original Article 20 December 2014 Pages: 353 - 363
Impact of pazopanib on docetaxel exposure: results of a phase I combination study with two different docetaxel schedules P. HambergR. H. J. MathijssenM. J. A. de Jonge Original Article 23 December 2014 Pages: 365 - 371
A phase 1 multiple-dose study of orteronel in Japanese patients with castration-resistant prostate cancer Kazuhiro SuzukiSeiichiro OzonoHideyuki Akaza Original Article Open access 24 December 2014 Pages: 373 - 380
Novel FTS-diamine/cinnamic acid hybrids inhibit tumor cell proliferation and migration and promote apoptosis via blocking Ras-related signaling in vitro Yong LingXinmei ZhaoYihua Zhang Original Article 27 December 2014 Pages: 381 - 392
Prevalence and clinical significance of potential drug–drug interaction in hematopoietic stem cell transplantation Danilo D. TrevisanJuliana B. SilvaMaria Helena M. Lima Original Article 27 December 2014 Pages: 393 - 400
Onartuzumab with or without bevacizumab in combination with weekly paclitaxel does not prolong QTc or adversely affect other ECG parameters in patients with locally recurrent or metastatic triple-negative breast cancer Marie T. BorinMeng ChenMark Stroh Original Article 27 December 2014 Pages: 401 - 410
Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells Vinayak KhattarJoshua FriedJaideep V. Thottassery Original Article 28 December 2014 Pages: 411 - 420
CEACAM1 and hollow spheroid formation modulate the chemosensitivity of colorectal cancer to 5-fluorouracil Naoyuki YamamotoShozo YokoyamaHiroki Yamaue Original Article 30 December 2014 Pages: 421 - 430
Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations Anne TheronRenaud PrudentAnnie Joubert Short Communication 30 December 2014 Pages: 431 - 437