Novel mechanism of cellular DNA topoisomerase II inhibition by the pyranonaphthoquinone derivatives α-lapachone and β-lapachone Preethi KrishnanKenneth F. Bastow Original Article Pages: 187 - 198
Plasma pharmacokinetics and cerebrospinal fluid penetration of thioguanine in children with acute lymphoblastic leukemia: a collaborative Pediatric Oncology Branch, NCI, and Children's Cancer Group study Original Article Pages: 199 - 205
A phase II study of dose-intense ifosfamide plus epirubicin with hematopoietic growth factors for the treatment of patients with advanced soft tissue sarcomas; a novel sequential schedule L. SerroneM. ZeuliF. Cognetti Original Article Pages: 206 - 210
Development, characterization and therapy of a disseminated model of childhood neuroblastoma in SCID mice Joyce ThompsonSylvie M. GuichardPeter J. Houghton Original Article Pages: 211 - 221
Cyclophosphamide metabolism in children following a 1-h and a 24-h infusion Steven M. YuleLisa PriceAlan V. Boddy Original Article Pages: 222 - 228
Cytocidal effect and DNA damage of nedaplatin: a mathematical model and analysis of experimental data Yasunari MiyagiKunihiro KawanishiTakafumi Kudo Original Article Pages: 229 - 235
Comparative study of a novel nucleoside analogue (Troxatyl, troxacitabine, BCH-4556) and AraC against leukemic human tumor xenografts expressing high or low cytidine deaminase activity Henriette GourdeauLucie BibeauTerry Bowlin Original Article Pages: 236 - 240
Bisimidazoacridones induce a potent cytostatic effect in colon tumor cells that sensitizes them to killing by UCN-01 Wieslaw M. CholodyTeresa Kosakowska-CholodyChristopher J. Michejda Original Article Pages: 241 - 249
Effects of PR-350, a newly developed radiosensitizer, on dihydropyrimidine dehydrogenase activity and 5-fluorouracil pharmacokinetics M. WatanabeT. TateishiS. Kobayashi Original Article Pages: 250 - 254
Primary breast tumor levels of suspected molecular determinants of cellular sensitivity to cyclophosphamide, ifosfamide, and certain other anticancer agents as predictors of paired metastatic tumor levels of these determinants Lakshmaiah SreeramaNorman E. Sládek Original Article Pages: 255 - 262
Pharmacokinetics of deguelin, a cancer chemopreventive agent in rats George O. UdeaniGuo-Min ZhaoJohn M. Pezzuto Original Article Pages: 263 - 268
Impact of carrier solutions on pharmacokinetics of intraperitoneal chemotherapy Original Article Pages: 269 - 276
Typhlitis (neutropenic enterocolitis) after a single dose of vinorelbine Eros FerrazzíSilvia TosoGiuseppina Giuliano Clinical Trial Report Pages: 277 - 279
UFT-induced haemolytic anaemia Amado J. Zurita SaavedraMatilde Navarro GarciaAdela Fernández Ortega Letter to the Editor Pages: 280 - 281
Bioavailability and phase II study of oral UFT plus leucovorin in patients with relapsed or refractory colorectal cancer Neal J. MeropolDaryl S. SonnichsenDiane Noel Erratum Pages: 282 - 282