A novel synthetic DNA minor groove binder, MS-247: antitumor activity and cytotoxic mechanism Y. MatsubaH. EdatsugiO. Nakanishi ORIGINAL ARTICLE Pages: 1 - 9
Pegylated liposome-encapsulated doxorubicin and cisplatin in the treatment of head and neck xenograft tumours Kevin J. HarringtonGail Rowlinson-BuszaJ. Simon Stewart ORIGINAL ARTICLE Pages: 10 - 18
Pharmacokinetics and toxicity of high-dose intravenous methotrexate in the treatment of leptomeningeal carcinomatosis Merry L. TetefKim A. MargolinEdward M. Newman ORIGINAL ARTICLE Pages: 19 - 26
Evaluation of toremifene for reversal of multidrug resistance in renal cell cancer patients treated with vinblastine Jeremy P. BraybrookeKatherine A. VallisDenis C. Talbot ORIGINAL ARTICLE Pages: 27 - 34
Effects of the aromatase inhibitor anastrozole on serum oestrogens in Japanese and Caucasian women Mitchell DowsettKirsteen DonaldsonRoger Yates ORIGINAL ARTICLE Pages: 35 - 39
Pharmacokinetics of 2-chloro-2′-deoxyadenosine administered subcutaneously or by continuous intravenous infusion Theodor SondereggerDaniel C. BetticherBernhard H. Lauterburg ORIGINAL ARTICLE Pages: 40 - 42
Dose escalation and pharmacokinetic study of irinotecan in combination with paclitaxel in patients with advanced cancer John R. MurrenKathleen PeccerilloYung chi Cheng ORIGINAL ARTICLE Pages: 43 - 50
Reduction of 5-fluorouracil (5-FU) gastrointestinal (GI) toxicity resulting from the protection of thymidylate synthase (TS) in GI tissue by repeated simultaneous administration of potassium oxonate (Oxo) in rats Kunihiro YoshisueKazue HironagaYasuro Kawaguchi ORIGINAL ARTICLE Pages: 51 - 56
Feasibility and pharmacokinetics of intraperitoneal suramin in advanced malignancy Anneke M. WestermannRia DubbelmanSjoerd Rodenhuis ORIGINAL ARTICLE Pages: 57 - 62
Primary treatment of low-grade non-Hodgkin's lymphoma using an all oral anthracycline-containing regimen, chlorambucil, idarubicin, dexamethasone (CID) – a phase II study Penelope TaylorGraham JacksonStephen Proctor ORIGINAL ARTICLE Pages: 63 - 68
Maximum tolerated doses of methotrexate and 7-hydroxy-methotrexate in a model of acute toxicity in rats Ole-Martin FuskevågChristel KristiansenJarle Aarbakke ORIGINAL ARTICLE Pages: 69 - 73
Selenium compounds prevent the induction of drug resistance by cisplatin in human ovarian tumor xenografts in vivo Paula B. CaffreyGerlad D. Frenkel ORIGINAL ARTICLE Pages: 74 - 78
A peptidomimetic inhibitor of ras functionality markedly suppresses growth of human prostate tumor xenografts in mice. Prospects for long-term clinical utility F. M. SirotnakLaura Sepp-LorenzinoHoward I. Scher ORIGINAL ARTICLE Pages: 79 - 83