Bcl-2 inhibits early apoptotic events and reveals post-mitotic multinucleation without affecting cell cycle arrest in human epithelial tumor cells exposed to etoposide Mary Jane ElliottKathleen M. MurphyRichard B. Lock ORIGINAL ARTICLE Pages: 1 - 11
Pharmacokinetics and pharmacodynamics of a novel protein kinase inhibitor, UCN-01 Noriaki KurataTakashi KuwabaraSatoshi Kobayashi ORIGINAL ARTICLE Pages: 12 - 18
Pharmacokinetics and biotransformations of oxaliplatin in comparison with ormaplatin following a single bolus intravenous injection in rats Feng R. LuoSteven D. WyrickStephen G. Chaney ORIGINAL ARTICLE Pages: 19 - 28
Comparative neurotoxicity of oxaliplatin, ormaplatin, and their biotransformation products utilizing a rat dorsal root ganglia in vitro explant culture model Feng R. LuoSteven D. WyrickStephen G. Chaney ORIGINAL ARTICLE Pages: 29 - 38
Phase I study of the cytotoxic agent N -[2-(dimethylamino)ethyl]acridine-4-carboxamide Michael R. McCrystalBarrie D. EvansBruce C. Baguley ORIGINAL ARTICLE Pages: 39 - 44
Plasma pharmacokinetics of N -[2-(dimethylamino)ethyl]acridine-4-carboxamide in a phase I trial Philip KestellIngrid C. DunlopBruce C. Baguley ORIGINAL ARTICLE Pages: 45 - 50
Metabolism of N -[2-(dimethylamino)ethyl]acridine-4-carboxamide in cancer patients undergoing a phase I clinical trial Philip C. SchofieldIain G. C. RobertsonBruce C. Baguley ORIGINAL ARTICLE Pages: 51 - 58
Cellular sensitization to cisplatin and carboplatin with decreased removal of platinum-DNA adduct by glucose-regulated stress Manabu YamadaAkihiro TomidaTakashi Tsuruo ORIGINAL ARTICLE Pages: 59 - 64
Local disposition kinetics of floxuridine after intratumoral and subcutaneous injection as monitored by [19F]-nuclear magnetic resonance spectroscopy in vivo Ruediger PortFriedrich HanischJens Zeller ORIGINAL ARTICLE Pages: 65 - 73
Phase I and pharmacokinetic analysis of high-dose tamoxifen and chemotherapy in normal and tumor-bearing dogs J. R. WaddleR. L. FineR. L. Page ORIGINAL ARTICLE Pages: 74 - 80
In vitro evaluation of flavopiridol, a novel cell cycle inhibitor, in bladder cancer Mark ChienMary AstumianWalter M. Stadler ORIGINAL ARTICLE Pages: 81 - 87
Omeprazole does not alter plasma methotrexate clearance Jeremy WhelanDenise HoarePauline Leonard LETTER TO THE EDITORS Pages: 88 - 89