Preclinical pharmacology of the natural product anticancer agent 10-hydroxycamptothecin, an inhibitor of topoisomerase I Ruiwen ZhangYufeng LiBrandon Chambless ORIGINAL ARTICLE Pages: 257 - 267
Metabolism and ribonucleotide reductase inhibition of (E )-2′-deoxy-2′-(fluoromethylene)cytidine, MDL 101,731, in human cervical carcinoma HeLa S3 cells Takeshi TakahashiAkiko NakashimaMasami Okabe ORIGINAL ARTICLE Pages: 268 - 274
Effect of 5-aza-2′-deoxycytidine and vitamin D3 analogs on growth and differentiation of human myeloid leukemic cells Benoit T. DoréChristine ChomienneRichard L. Momparler ORIGINAL ARTICLE Pages: 275 - 280
Phase I clinical and pharmacokinetic study of S9788, a new multidrug-resistance reversal agent given alone and in combination with doxorubicin to patients with advanced solid tumors Brigitte TranchandGilles CatimelClaude Ardiet ORIGINAL ARTICLE Pages: 281 - 291
The antiproliferative action of a melphalan hexapeptide with collagenase-cleavable site F. TimárJ. BotyánszkiA. Jeney ORIGINAL ARTICLE Pages: 292 - 298
Quantitation of dolastatin-10 using HPLC/electrospray ionization mass spectrometry: application in a phase I clinical trial D. A. GarteizT. MaddenR. A. Newman ORIGINAL ARTICLE Pages: 299 - 306
Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a panel of eight solid-tumor cell lines in vitro Jianguo MaMarc MaliepaardJan H. M. Schellens ORIGINAL ARTICLE Pages: 307 - 316
Distribution of estramustine in the BT4C rat glioma model M. JohanssonA. Tommy BergenheimRoger Henriksson ORIGINAL ARTICLE Pages: 317 - 325
The antineoplastic ether lipid, s-phosphonate, selectively induces apoptosis in human leukemic cells and exhibits antiangiogenic and apoptotic activity on the chorioallantoic membrane of the chick embryo John K. JacksonHelen M. BurtAnn Marie Oktaba ORIGINAL ARTICLE Pages: 326 - 332
Cisplatin, epirubicin, and lonidamine combination regimen as first-line chemotherapy for metastatic breast cancer: a pilot study L. DogliottiS. DaneseG. Porcile CLINICAL TRIAL REPORT Pages: 333 - 338
Length increase of the side chain of idoxifene does not improve its antagonistic potency in breast-cancer cell lines Lu JinNicole LegrosMichael Jarman SHORT COMMUNICATION Pages: 339 - 342
Effects of haemopoietic growth factors in combination with etoposide on sister chromatid exchange frequencies in peripheral blood mononuclear cells Wai M. LiuClare BamfordSimon P. Joel SHORT COMMUNICATION Pages: 343 - 346
