1. Formation, Intracellular distribution and efflux of glutathione–bimane conjugates in drug-sensitive and -resistant MCF-7 cells

   • Kevin K. Millis
   • Stephen A. Lesko
   • M. P. Gamcsik

   ORIGINAL ARTICLE Pages: 101 - 111

2. Enhancement of therapeutic efficacy of bleomycin by incorporation into biodegradable poly-d,l-lactic acid

   • Toru Kumanohoso
   • Shoji Natsugoe
   • Takashi Aikou

   ORIGINAL ARTICLE Pages: 112 - 116

3. Inter- and intraindividual variation in dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells

   • Jean L. Grem
   • Lorrin K. Yee
   • Carmen J. Allegra

   ORIGINAL ARTICLE Pages: 117 - 125

4. Disposition of leucovorin and its metabolites in dietary folic acid-deplete mice – comparison between tumor, liver and plasma

   • K. Raghunathan
   • John C. Schmitz
   • D. G. Priest

   ORIGINAL ARTICLE Pages: 126 - 130

5. Chemical characterization and comparative cellular effects of meta-iodobenzyl guanidine and benzyl guanidine

   • Joop D. Van den Berg
   • Lou A. Smets
   • Henny van Rooij

   ORIGINAL ARTICLE Pages: 131 - 137

6. Mechanism of action and spectrum of cell types susceptible to doxorubicin photochemotherapy

   • Jian-Ping Gao
   • Karl W. Lanks
   • Bai-Tang Lai

   ORIGINAL ARTICLE Pages: 138 - 142

7. A Bayesian dosing method for carboplatin given by continuous infusion for 120 h

   • P. Guillet
   • S. Monjanel
   • R. Favre

   ORIGINAL ARTICLE Pages: 143 - 149

8. Probenecid reverses multidrug resistance in multidrug resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells

   • S. Gollapudi
   • Choong H. Kim
   • Sudhir Gupta

   ORIGINAL ARTICLE Pages: 150 - 158

9. Cell cycle perturbations in cisplatin-sensitive and resistant human ovarian carcinoma cells following treatment with cisplatin and low dose rate irradiation

   • D. E. Wilkins
   • C. E. Ng
   • G. P. Raaphorst

   ORIGINAL ARTICLE Pages: 159 - 166

10. In vitro studies of the hyperthermic enhancement of activated ifosfamide (4-hydroperoxy-ifosfamide) and glucose isophosphoramide mustard

    • Matthew E. Kutz
    • D. L. Mulkerin
    • H. Ian Robins

    ORIGINAL ARTICLE Pages: 167 - 171

11. Effects of the polyamine analogues BE-4-4-4-4, BE-3-7-3, and BE-3-3-3 on the proliferation of three prostate cancer cell lines

    • Lisa Jeffers
    • Dawn Church
    • G. Wilding

    ORIGINAL ARTICLE Pages: 172 - 179

12. In vitro antitumor activity of 3′-desamino-3′(2-methoxy-4-morpholinyl) doxorubicin on human melanoma cells sensitive or resistant to triazene compounds

    • Ester Alvino
    • Sara Gilberti
    • Stefania D'Atri

    SHORT COMMUNICATION Pages: 180 - 184

13. Influence of age on toremifene pharmacokinetics

    • Eero A. Sotaniemi
    • M. I. Anttila

    SHORT COMMUNICATION Pages: 185 - 188