A two-step targeting approach for delivery of doxorubicin-loaded liposomes to tumour cells in vivo Shane A. LongmanPieter R. CullisMarcel B. Bally Original Article Pages: 91 - 101
The influence of ageing on cisplatin pharmacokinetics in lung cancer patients with normal organ function Nobuyuki YamamotoTomohide TamuraNagahiro Saijo Original Article Pages: 102 - 106
Metabolism of taxol by human and rat liver in vitro: A screen for drug interactions and interspecies differences Carlos A. Jamis-DowRaymond W. KleckerJerry M. Collins Original Article Pages: 107 - 114
Preclinical pharmacology of cholera toxin Joel M. ReidJohn W. BensonMatthew M. Ames Original Article Pages: 115 - 120
Intrathecal administration of topotecan in nonhuman primates Susan M. BlaneyDiane E. ColeFrank M. Balis Original Article Pages: 121 - 124
Cytochrome P-450IID6 phenotyping in cancer patients: debrisoquin and dextromethorphan as probes Lowell B. AnthonyThomas J. BoeveKenneth R. Hande Original Article Pages: 125 - 128
Comparative in vitro cytotoxic effects of taxol and its major human metabolite 6α-hydroxytaxol Gondi KumarSwapan RayKapil Bhalla Original Article Pages: 129 - 135
The absorption of 6-mercaptopurine from 6-mercaptopurine riboside in rat small intestine: effect of phosphate A. M. PenningtonJ. R. Bronk Original Article Pages: 136 - 142
Induction of tumour necrosis factor-α by single and repeated doses of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid Martin PhilpottBruce C. BaguleyLai-Ming Ching Original Article Pages: 143 - 148
Antibiotic C3368-A, a fungus-derived nucleoside transport inhibitor, potentiates the activity of antitumor drugs Jian SuYong-su ZhenJi-lan Hu Original Article Pages: 149 - 154
Plasma nitrate clearance in mice: modeling of the systemic production of nitrate following the induction of nitric oxide synthesis Edina VeszelovszkyNicholas H. G. HolfordBruce C. Baguley Original Article Pages: 155 - 159
Tolerance, safety, and kinetics of the new antineoplastic compound dexniguldipine-HCl after oral administration: a phase I dose-escalation trial D. UkenaC. BoewerG. W. Sybrecht Original Article Pages: 160 - 164
Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivo Sylvia A. HoldenBeverly A. TeicherAndre Rosowsky Original Article Pages: 165 - 171
Treatment of advanced, high-grade soft-tissue sarcoma with ifosfamide and continuous-infusion etoposide Gunnar SæterKristian TalleØyvin P. Solheim Clinical Trial Report Pages: 172 - 175
Identification and kinetics of a β-glucuronide metabolite of SN-38 in human plasma after administration of the camptothecin derivative irinotecan Laurent P. RivoryJacques Robert Short Communication Pages: 176 - 179