1. Phase I clinical trial of cisplatin given i.v. with 5-fluorouracil and high-dose folinic acid

   • James L. Abbruzzese
   • Robert Amato
   • Philip Frost

   OriginalPaper Pages: 159 - 162

2. The influence of Na⁺, K⁺-pump blockade on doxorubicin-mediated cytotoxicity and DNA strand breakage in human tumor cells

   • Theodore S. Lawrence
   • Mary A. Davis

   OriginalPaper Pages: 163 - 167

3. Modulation of the cytotoxic mechanism of 6-thioguanine by 4-amino-5-imidazolecarboxamide

   • Jonathan Maybaum
   • Catherine W. Morgans
   • Clare E. Rogers

   OriginalPaper Pages: 168 - 172

4. The chemotherapeutic potential of glycol alkyl ethers: structure-activity studies of nine compounds in a Fischer-rat leukemia transplant model

   • Michael P. Dieter
   • Charles W. Jameson
   • Andrew G. Braun

   OriginalPaper Pages: 173 - 180

5. Increased therapeutic effect on metastatic liver tumors in rats of two-route chemotherapy usingcis-diamminedichloroplatinum (II) and its antidote, sodium thiosulfate, with temporary clamping of the abdominal aorta

   • Keitaro Hasuda
   • Hiroaki Kobayashi
   • Tsuneo Baba

   OriginalPaper Pages: 181 - 187

6. Quantitative subcellular distribution of platinum in rat tissues following i. v. bolus and i. v. infusion of cisplatin

   • Rajesh Parti
   • Walter Wolf

   OriginalPaper Pages: 188 - 192

7. Antitumor activity of MST-16, a novel derivative of bis(2,6-dioxopiperazine), in murine tumor models

   • Toshiharu Narita
   • Shin-ichi Yaguchi
   • Shigeru Tsukagoshi

   OriginalPaper Pages: 193 - 197

8. Slow penetration of anthracyclines into spheroids and tumors: a therapeutic advantage?

   • Ralph E. Durand

   OriginalPaper Pages: 198 - 204

9. Tissue distribution of [¹⁸F]-5-fluorouracil in mice: effects of route of administration, strain, tumour and dose

   • Gerard W. M. Visser
   • Geertrui C. M. Gorree
   • Jacobus D. M. Herscheid

   OriginalPaper Pages: 205 - 209

10. Extracorporeal hemofiltration: a model for decreasing systemic drug exposure with intra-arterial chemotherapy

    • Roger A. Graham
    • Zahid H. Siddik
    • David C. Hohn

    OriginalPaper Pages: 210 - 214

11. Evaluation ofp-F-Phe-m-bis-(2-chloroethyl)amino-l-Phe-Met-ethoxy HCl against transplantable and spontaneous murine neoplasia

    • Mary Jane Yagi
    • J. George Bekesi

    OriginalPaper Pages: 215 - 220

12. Phase II study of tallysomycin S₁₀b in patients with advanced colorectal cancer

    • C. Nicaise
    • J. Ajani
    • I. Krakoff

    OriginalPaper Pages: 221 - 222

13. Evaluation of continuous-infusion alpha-difluoromethylornithine therapy for colorectal carcinoma

    • Jaffer A. Ajani
    • David M. Ota
    • Kenji Nishioka

    OriginalPaper Pages: 223 - 226

14. Cardiovascular autonomic function in anthracycline-treated breast cancer patients

    • Maria Viniegra
    • Marcelo Marchetti
    • Pedro M. Politi

    OriginalPaper Pages: 227 - 231

15. Carboplatin is ototoxic

    • Ian C. S. Kennedy
    • Bernard M. Fitzharris
    • Christopher H. Atkinson

    Short Communication Pages: 232 - 234

16. Acute nonlymphocytic leukemia following chemotherapy with cisplatin and etoposide for non-small-cell carcinoma of the lung: case report

    • Daniel Brenez
    • Jacques Devriendt
    • Jacqueline Schmerber

    Short Communication Pages: 235 - 236

17. Phase I study of mitozolomide on a once daily for 5 days schedule

    • Jan H. Schornagel
    • Godelaine Simonetti
    • J. Gordon McVie

    Short Communication Pages: 237 - 238

18. A pilot study of metoclopramide, dexamethasone, diphenhydramine and acupuncture in women treated with cisplatin

    • L. Aglietti
    • F. Roila
    • A. Del Favero

    Short Communication Pages: 239 - 240