Volume 55, Issue 4, April 2005

In this issue (14 articles)

1. 

   Original Article

   Patupilone (epothilone B, EPO906) and imatinib (STI571, Glivec) in combination display enhanced antitumour activity in vivo against experimental rat C6 glioma

   T. O’Reilly, M. Wartmann, S.-M. Maira… Pages 307-317

2. 

   Original Article

   Isolated pelvic perfusion: plasma pharmacokinetics depend primarily on drug dosage and not the type of drug

   James F. Belliveau, Elisabeth Arevalo, Hank Griffin… Pages 318-322

3. 

   Original Article

   A possible mechanism for the long-lasting antitumor effect of the macromolecular conjugate DE-310: mediation by cellular uptake and drug release of its active camptothecin analog DX-8951

   Yusuke Ochi, Yoshinobu Shiose, Hiroshi Kuga… Pages 323-332

4. 

   Original Article

   Role of glutathione and nucleotide excision repair in modulation of cisplatin activity with O⁶-benzylguanine

   Melissa L. Fishel, Michael P. Gamcsik… Pages 333-342

5. 

   Original Article

   Endometrial K-ras mutations in postmenopausal breast cancer patients treated with adjuvant tamoxifen or toremifene

   Mika Wallén, Eija Tomás, Tapio Visakorpi… Pages 343-346

6. 

   Original Article

   Interactions of carboxypeptidase G₂ with 6S-leucovorin and 6R-leucovorin in vitro: implications for the application in case of methotrexate intoxications

   Georg Hempel, Rainer Lingg, Joachim Boos Pages 347-353

7. 

   Original Article

   Phase I study of weekly (day 1 and 8) docetaxel in combination with capecitabine in patients with advanced solid malignancies

   Ramesh K. Ramanathan, Sakkaraiappan Ramalingam… Pages 354-360

8. 

   Original Article

   Biochemical modulation of cytarabine triphosphate by clofarabine

   Todd Cooper, Mary Ayres, Billie Nowak… Pages 361-368

9. 

   Original Article

   RETRACTED ARTICLE: Quinoxaline 1,4-dioxides induce G₂/M cell cycle arrest and apoptosis in human colon cancer cells

   Hala U. Gali-Muhtasib, Mona Diab-Assaf… Pages 369-378

10. 

    Original Article

    Imatinib pharmacokinetics in patients with gastrointestinal stromal tumour: a retrospective population pharmacokinetic study over time. EORTC Soft Tissue and Bone Sarcoma Group

    Ian Judson, Peiming Ma, Bin Peng, Jaap Verweij… Pages 379-386

11. 

    Original Article

    Does cisplatin (CDDP) function as a modulator of 5-fluorouracil (5-FU) antitumor action? A study based on a clinical trial

    Satoshi Matsusaka, Tomofumi Nagareda… Pages 387-392

12. 

    Original Article

    Gefitinib (“Iressa”, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells

    Osamu Kishida, Yoshiji Miyazaki, Yoko Murayama… Pages 393-403

13. 

    Short Communication

    Bioavailability and pharmacokinetics of the investigational anticancer agent XK469 (NSC 698215) in rats following oral and intravenous administration

    Ramesh R. Boinpally, Sen-Lin Zhou… Pages 404-407

14. 

    Acknowledgement to Reviewers

    Acknowledgement to Reviewers 2004

    Pages 408-410