1. The combi-targeting concept: a novel 3,3-disubstituted nitrosourea with EGFR tyrosine kinase inhibitory properties

   • Qiyu Qiu
   • Fabienne Dudouit
   • Bertrand J. Jean-Claude

   Original Article Pages: 1 - 10

2. Differential responses of EGFR-/AGT-expressing cells to the "combi-triazene" SMA41

   • Stephanie L. Matheson
   • James P. McNamee
   • Bertrand J. Jean-Claude

   Original Article Pages: 11 - 20

3. Evidence for the involvement of ET_B receptors in ET-1-induced changes in blood flow to the rat breast tumor

   • Aarati Rai
   • Anil Gulati

   Original Article Pages: 21 - 28

4. Clinical significance of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in transitional cell cancer

   • Yasuhiro Hirano
   • Shinji Kageyama
   • Kimio Fujita

   Original Article Pages: 29 - 35

5. Ototoxicity, nephrotoxicity and pharmacokinetics of cisplatin and its monohydrated complex in the guinea pig

   • Andreas Ekborn
   • Annika Lindberg
   • Hans Ehrsson

   Original Article Pages: 36 - 42

6. Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

   • Bronwyn G. Siim
   • Alan E. Lee
   • William R. Wilson

   Original Article Pages: 43 - 52

7. Delivery of interleukin-12 in gelatin hydrogels effectively suppresses development of transplanted colonal carcinoma in mice

   • Lili Liu
   • Takeo Sakaguchi
   • Katsuyoshi Hatakeyama

   Original Article Pages: 53 - 57

8. A study to evaluate the pharmacokinetics of oral 5-fluorouracil and eniluracil after concurrent administration to patients with refractory solid tumours and varying degrees of renal impairment (FUMA1005)

   • Anne O'Donnell
   • Cornelis J. Punt
   • Philip Beale

   Original Article Pages: 58 - 66

9. Biological properties of jatrophane polyesters, new microtubule-interacting agents

   • Antonella Miglietta
   • Ludovica Gabriel
   • Claudia Bocca

   Original Article Pages: 67 - 74

10. Suppressive effect of Astragalus membranaceus Bunge on chemical hepatocarcinogenesis in rats

    • Rutao Cui
    • Jinchun He
    • Hong Shen

    Original Article Pages: 75 - 80

11. Pilot study of pegylated interferon-alpha 2b in patients with essential thrombocythemia

    • Yesid Alvarado
    • Jorge Cortes
    • Francis J. Giles

    Short Communication Pages: 81 - 86

12. Pilot study of Mylotarg, idarubicin and cytarabine combination regimen in patients with primary resistant or relapsed acute myeloid leukemia

    • Yesid Alvarado
    • Apostolia Tsimberidou
    • Francis J. Giles

    Short Communication Pages: 87 - 90

13. Sensitivity to cisplatin treatment of human K1 thyroid carcinoma cell lines with altered p53 function

    • Jocelyn Céraline
    • Gaël Deplanque
    • Claudine Klein-Soyer

    Short Communication Pages: 91 - 95