1. On the search for new anticancer drugs 14: The plasma pharmacokinetics and tissue distribution of spin-labeled thio-TEPA (SL-O-TT)

   • Peter L. Gutierrez
   • Brian E. Cohen
   • Merrill J Egorin

   Original Articles Pages: 185 - 191

2. Regional targeting of Bisantrene by directed intravascular precipitation

   • John S. Kovach
   • Martin Buck
   • Michael M. Lieber

   Original Articles Pages: 192 - 195

3. Effects of difluoromethylornithine on proliferation, polyamine content and plating efficiency of cultured human carcinoma cells

   • Jerome Seidenfeld

   Original Articles Pages: 196 - 202

4. Evaluation of the nephrotoxicity of iproplatin (CHIP) in comparison to cisplatin by the measurement of urinary enzymes

   • Lakshmi Pendyala
   • Stefan Madajewicz
   • Patrick J. Creaven

   Original Articles Pages: 203 - 207

5. In vitro evaluation of anticancer drugs in relation to development of drug resistance in the human tumor clonogenic assay

   • Katsuhiro Inoue
   • Taketo Mukaiyama
   • Makoto Ogawa

   Original Articles Pages: 208 - 213

6. Lack of enhanced cytotoxicity of cultured L1210 cells using folinic acid in combination with sequential methotrexate and fluorouracil

   • Lynn L. Danhauser
   • Robert Heimer
   • Ed Cadman

   Original Articles Pages: 214 - 219

7. Clinical pharmacology of oral intermediate-dose methotrexate with or without probenecid

   • Michael B. Lilly
   • George A. Omura

   Original Articles Pages: 220 - 222

8. A low density lipoprotein — methotrexate covalent complex and its activity against L1210 cells in vitro

   • G. W. Halbert
   • J. F. B. Stuart
   • A. T. Florence

   Original Articles Pages: 223 - 227

9. Inactivation of cis-diamminedichloroplatinum (II) in blood and protection of its toxicity by sodium thiosulfate in rabbits

   • Yukihide Iwamoto
   • Toyokazu Kawano
   • Tsuneo Baba

   Original Articles Pages: 228 - 232

10. Phase I clinical trial of fludarabine phosphate (F-ara-AMP)

    • Ephraim S. Casper
    • Abraham Mittelman
    • Charles W. Young

    Original Articles Pages: 233 - 235

11. Protective effect of testosterone of 5β-dihydrotestosterone pretreatment on CFU-E numbers in busulfan-treated rabbits

    • Bruno Mödder
    • Guntram Fütterer

    Original Articles Pages: 236 - 239

12. A microtitre cytotoxicity assay useful for the discovery of fermentation-derived antitumor agents

    • Joseph J. Catino
    • Donna M. Francher
    • Dale A. Stringfellow

    Original Articles Pages: 240 - 243

13. Similar changes in cardiac morphology and DNA synthesis induced by doxorubicin and 4′-epi-doxorubicin

    • Karsten Wassermann
    • Kjeld Mølgaard
    • Eva Steiness

    Original Articles Pages: 244 - 252

14. Assessment of ventricular function by radionuclide angiography in patients receiving 4′-epidoxorubicin and mitoxantrone

    • Daniel A. Vorobiof
    • Mario Iturralde
    • Geoffrey Falkson

    Original Articles Pages: 253 - 257

15. A phase II study of ifosfamide in children with recurrent solid tumours

    • C. R. Pinkerton
    • H. Rogers
    • J. Pritchard

    Original Articles Pages: 258 - 262

16. High dose melphalan in children with advanced malignant disease

    • J. Ninane
    • R. Baurain
    • G. Cornu

    Original Articles Pages: 263 - 267

17. The effects of multiple combination chemotherapy with vincristine, cyclophosphamide (Endoxan), methotrexate, 5-fluorouracil, adriamycin and prednisolone (VEMFAH) for advanced breast cancer

    • Tetsuhito Kojima
    • Akira Hoshino
    • Yoshikazu Dohke

    Original Articles Pages: 268 - 271

18. Insulin effects on methotrexate polyglutamate synthesis and enzyme binding in cultured human breast cancer cells

    • Richard L. Schilsky
    • Frederick S. Ordway

    Original Articles Pages: 272 - 277

19. The modulating effects of flurbiprofen on adriamycin plus vincristine or vindesine in the treatment of advanced breast cancer

    • D. J. Perez
    • T. J. Powles
    • R. C. Coombes

    Original Articles Pages: 278 - 282

20. Cisplatinum and Bleomycin for advanced or recurrent squamous cell carcinoma of the head and neck: a randomised factorial phase III controlled trial

    • R. P. Morton
    • F. Rugman
    • P. M. Stell

    Original Articles Pages: 283 - 289

21. Comparison of serum and cerebrospinal fluid levels of methotrexate in man during high-dose chemotherapy for aggressive non-Hodgkin's lymphoma

    • Nigel L. Gilchrist
    • James Caldwell
    • William Fitch

    Original Articles Pages: 290 - 294

22. Nonlinear renal clearance of ultrafilterable platinum in patients treated with cis-dichlorodiammineplatinum (II)

    • Phillip A Reece
    • Irene Stafford
    • P. Grantley Gill

    Original Articles Pages: 295 - 299

23. Phase II study of combination bleomycin, vincristine and high-dose methotrexate (BOM) with leucovorin rescue in advanced squamous cell carcinoma of the anal canal

    • Nils Wilking
    • Nicholas Petrelli
    • Arnold Mittelman

    Original Articles Pages: 300 - 302

24. High-dose cyclophosphamide and VP 16 as late dosage intensification therapy for small cell carcinoma of lung

    • David Cunningham
    • Stephen W. Banham
    • Alan K. Burnett

    Original Articles Pages: 303 - 306

25. Mesna does not reduce cisplatin induced nephrotoxicity in the rat

    • Barbara C. Millar
    • Zahid H. Siddik
    • Sally Jinks

    Short Communication Pages: 307 - 309

26. Platinum concentration in human tumors of head and neck, uterine cervix, and breast following treatment with cisplatin

    • B. Hecquet
    • P. Vennin
    • A. Demaille

    Short Communication Pages: 310 - 312