Clinical translation and regulatory aspects of CAR/TCR-based adoptive cell therapies—the German Cancer Consortium approach Angela M. KrackhardtBrigitte AnlikerMartina Schüssler-Lenz Review 29 January 2018 Pages: 513 - 523
Human c-SRC kinase (CSK) overexpression makes T cells dummy Else Marit InderbergNadia MensaliSébastien Wälchli Original Article 16 December 2017 Pages: 525 - 536
IL-6 and IL-10 are associated with good prognosis in early stage invasive breast cancer patients Narmeen AhmadAula AmmarStewart G. Martin Original Article Open access 18 December 2017 Pages: 537 - 549
Cytosolic high-mobility group box protein 1 (HMGB1) and/or PD-1+ TILs in the tumor microenvironment may be contributing prognostic biomarkers for patients with locally advanced rectal cancer who have undergone neoadjuvant chemoradiotherapy Chih-Yang HuangShu-Fen ChiangK. S. Clifford Chao Original Article 21 December 2017 Pages: 551 - 562
Anti-PD-1-induced high-grade hepatitis associated with corticosteroid-resistant T cells: a case report Helen M. McGuireElena ShklovskayaPeter Hersey Original Article Open access 30 December 2017 Pages: 563 - 573
Ex vivo-expanded NK cells from blood and ascites of ovarian cancer patients are cytotoxic against autologous primary ovarian cancer cells Tina NhamSophie M. PoznanskiAli A. Ashkar Original Article 03 January 2018 Pages: 575 - 587
Reduction of myeloid-derived suppressor cells reinforces the anti-solid tumor effect of recipient leukocyte infusion in murine neuroblastoma-bearing allogeneic bone marrow chimeras Isabelle Dierckx de CasterléSabine FeveryBen Sprangers Original Article 03 January 2018 Pages: 589 - 603
A novel biologic platform elicits profound T cell costimulatory activity and antitumor immunity in mice Joseph M. RyanPayal MittalAnthony T. Vella Original Article 11 January 2018 Pages: 605 - 613
The role of interleukin-2, all-trans retinoic acid, and natural killer cells: surveillance mechanisms in anti-GD2 antibody therapy in neuroblastoma Rosa NguyenJim HoustonMichael A. Dyer Original Article 11 January 2018 Pages: 615 - 626
Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model Alex AllenChuan WangNatalia Savelyeva Original Article Open access 12 January 2018 Pages: 627 - 638
Combined sublethal irradiation and agonist anti-CD40 enhance donor T cell accumulation and control of autochthonous murine pancreatic tumors Lindsay K. Ward-KavanaghKathleen M. KokolusTodd D. Schell Original Article 13 January 2018 Pages: 639 - 652
Abscopal effects of radiotherapy and combined mRNA-based immunotherapy in a syngeneic, OVA-expressing thymoma mouse model Lucas BaslerAleksandra KowalczykStephan M. Huber Original Article 16 January 2018 Pages: 653 - 662
Epstein–Barr virus strain heterogeneity impairs human T-cell immunity Ana CiracSimon StützleJosef Mautner Original Article 27 January 2018 Pages: 663 - 674
An IL-15 superagonist/IL-15Rα fusion complex protects and rescues NK cell-cytotoxic function from TGF-β1-mediated immunosuppression Rika FujiiCaroline JochemsJames W. Hodge Original Article 01 February 2018 Pages: 675 - 689
N-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner Matthew J. ScheffelGina ScurtiChristina Voelkel-Johnson Original Article 02 February 2018 Pages: 691 - 702