PD-1 blockade does not improve efficacy of EpCAM-directed CAR T-cell in lung cancer brain metastasis Jens BlobnerLaura DenglerLouisa von Baumgarten Research Open access 03 October 2024 Article: 255
PD-L1+ neutrophils induced NETs in malignant ascites is a potential biomarker in HCC Xiaoyu SunYaoqi GuiBo Wang Research Open access 03 October 2024 Article: 254
GPCRs: emerging targets for novel T cell immune checkpoint therapy Kaitlyn DickinsonElliott J. YeeYuwen Zhu Review Open access 03 October 2024 Article: 253
Immunotherapy may be more appropriate for ERBB2 low-expressing extramammary paget’s disease patients: a prognosis analysis and exploration of targeted therapy and immunotherapy of extramammary paget’s disease patients Jiawen YangYurong ChenYing Yuan Research Open access 03 October 2024 Article: 252
Exploring the impact of durvalumab on biliary tract cancer: insights from real-world clinical data Patrick ReimannIlektra-Antonia MavroeidiBernhard Doleschal Research Open access 03 October 2024 Article: 251
Multi-omics analysis and response prediction of PD-1 monoclonal antibody containing regimens in patients with relapsed/refractory diffuse large B-cell lymphoma Xinrui ChenYan QinYuankai Shi Research Open access 03 October 2024 Article: 250
Effectiveness, safety, and biomarker analysis of lenvatinib plus toripalimab as chemo-free therapy in advanced intrahepatic cholangiocarcinoma: a real-world study Shanshan WangJiashuo ChaoHaitao Zhao Research Open access 03 October 2024 Article: 249
Enhanced anti-tumor efficacy of electroporation (EP)-mediated DNA vaccine boosted by allogeneic lymphocytes in pre-established tumor models Sanyuan ShiLuchen ZhangYuhong Xu Research Open access 03 October 2024 Article: 248
HLA-G neo-expression modifies genetic programs governing tumor cell lines Diana Tronik-Le RouxMarina DaouyaEdgardo D. Carosella Research Open access 03 October 2024 Article: 247
Development and validation of a new tool to estimate early mortality in patients with advanced cancer treated with immunotherapy Andrea De GiglioAlessandro LeonettiAndrea Ardizzoni Research Open access 03 October 2024 Article: 246
NitraTh epitope-based neoantigen vaccines for effective tumor immunotherapy Wanli ZhangXupeiyao ShiWenbing Yao Research Open access 03 October 2024 Article: 245
Toripalimab combined with definitive chemoradiotherapy for locally advanced cervical squamous cell carcinoma patients (TRACE): A single-arm, phase I/II trial Dan OuRong CaiHao-Ping Xu Research Open access 03 October 2024 Article: 244
Dose-escalation, tolerability, and efficacy of intratumoral and subcutaneous injection of hemagglutinating virus of Japan envelope (HVJ-E) against chemotherapy-resistant malignant pleural mesothelioma: a clinical trial Kazuma SakuraMuneyoshi KuroyamaYasufumi Kaneda Research Open access 03 October 2024 Article: 243
Therapeutic antibodies in oncology: an immunopharmacological overview Karen Toledo-StuardoCarolina H. RibeiroMarĂa Carmen Molina Review Open access 03 October 2024 Article: 242
A random survival forest-based pathomics signature classifies immunotherapy prognosis and profiles TIME and genomics in ES-SCLC patients Yuxin JiangYueying ChenPing Zhan Research Open access 03 October 2024 Article: 241
Efficacy and safety of lenvatinib combined with anti-PD-1 antibodies plus GEMOX chemotherapy as non-first-line systemic therapy in advanced gallbladder cancer Yang TanKai LiuHaitao Zhao Research Open access 03 October 2024 Article: 240
INTASYL self-delivering RNAi decreases TIGIT expression, enhancing NK cell cytotoxicity: a potential application to increase the efficacy of NK adoptive cell therapy against cancer Melissa MaxwellDingxue YanElfriede Noessner Research Open access 03 October 2024 Article: 239
The relevance of tumor target expression levels on IgA-mediated cytotoxicity in cancer immunotherapy Chilam ChanNĂºria CasalĂ© CabanesJeanette H. W. Leusen Research Open access 03 October 2024 Article: 238
Tumor immunogenicity regulates host immune responses, and conventional dendritic cell type 2 uptakes the majority of tumor antigens in an orthotopic lung cancer model Ki-Hyun KimSeung-jae KimGye Young Park Brief Report Open access 03 October 2024 Article: 237
Correction to: Inhibition of glycolysis enhances the efficacy of immunotherapy via PDK‑mediated upregulation of PD‑L1 Ruizhi ZhangGan MaoWei Li Correction Open access 17 September 2024 Article: 236
Bronchoalveolar lavage fluid analysis in patients with checkpoint inhibitor pneumonitis Ruxuan ChenYujie ShiMengzhao Wang Research Open access 13 September 2024 Article: 235
Genomic and molecular alterations associated with primary resistance to immune checkpoint inhibitors Jyoti MalhotraSubhajyoti DeVictoria Villaflor Review Open access 13 September 2024 Article: 234
Single-cell RNA sequencing to map tumor heterogeneity in gastric carcinogenesis paving roads to individualized therapy Jiao XuBixin YuJin Yang Review Open access 13 September 2024 Article: 233
Recent clinical researches and technological development in TIL therapy Satoko MatsuedaLei ChenFuli Yu Review Open access 12 September 2024 Article: 232
A monoclonal antibody recognizing CD98 on human embryonic stem cells shows anti-tumor activity in hepatocellular carcinoma xenografts Keunpyo LimSan Ha HanChun Jeih Ryu Research Open access 11 September 2024 Article: 231
Adjuvant chemoradiotherapy plus pembrolizumab for locally advanced esophageal squamous cell carcinoma with high risk of recurrence following neoadjuvant chemoradiotherapy: a single-arm phase II study Jhe-Cyuan GuoTa-Chen HuangChih-Hung Hsu Research Open access 09 September 2024 Article: 230
Secretome and immune cell attraction analysis of head and neck cancers Tara MuijlwijkNiels E. WondergemRieneke van de Ven Research Open access 09 September 2024 Article: 229
Disruptions in antigen processing and presentation machinery on sarcoma Salvatore Lorenzo RenneLaura Sama’Ferdinando Carlo Maria Cananzi Research Open access 09 September 2024 Article: 228
Adding-on nivolumab to chemotherapy-stabilized patients is associated with improved survival in advanced pancreatic ductal adenocarcinoma Shih-Hung YangSung-Hsin KuoKun-Huei Yeh Research Open access 09 September 2024 Article: 227
Triple therapy boosts survival in NSCLC patients with brain metastases: a retrospective cohort study of chemotherapy, ICIs, and antiangiogenic agents Dingyi YangErha MunaiXiao-Dong Zhu Research Open access 06 September 2024 Article: 226
Impaired TGF-β signaling via AHNAK family mutations elicits an esophageal cancer subtype with sensitivities to genotoxic therapy and immunotherapy Zihang MaiKongjia LuoJianhua Fu Research Open access 05 September 2024 Article: 225
Correction to: Impact of fludarabine and treosulfan on ovarian tumor cells and mesothelin chimeric antigen receptor T cells Ibrahim El-SerafIsabella Micallef NilssonIsabelle Magalhaes Correction Open access 05 September 2024 Article: 224
Distribution characteristics of immune infiltration and lymphovascular invasion in patients with breast cancer skin recurrence Danyang ZhouMei LiRuoxi Hong Research Open access 05 September 2024 Article: 223
A comprehensive and longitudinal evaluation of the different populations of lymphoid and myeloid cells in the peripheral blood of patients treated with chemoradiotherapy for head and neck cancer Jens von der GrĂ¼nMartina BrogliePanagiotis Balermpas Research Open access 05 September 2024 Article: 222
Oncolytic virotherapy augments self-maintaining natural killer cell line cytotoxicity against neuroblastoma Colin H. QuinnJanet R. JulsonElizabeth A. Beierle Research Open access 05 September 2024 Article: 221
Efficacy of durvalumab plus chemotherapy in advanced biliary duct cancer and biomarkers exploration Yunxin LuYin JinDongsheng Zhang Research Open access 05 September 2024 Article: 220
SAFFRON-104: a phase Ib/II study of sitravatinib alone or with tislelizumab in advanced hepatocellular carcinoma and gastric cancer/gastroesophageal junction cancer Jin LiYuxian BaiShukui Qin Research Open access 05 September 2024 Article: 219
Stat3-mediated Atg7 expression regulates anti-tumor immunity in mouse melanoma Sarah M. ZimmermanErin SuhGeorge P. Souroullas Brief Report Open access 05 September 2024 Article: 218
Immunogenomic features of radiologically distinctive nodules in multiple primary lung cancer Mei-Cheng ChenHao-Shuai YangYing Zhu Research Open access 05 September 2024 Article: 217
The short-term efficacy of neoadjuvant SOX versus SOX plus immune checkpoint inhibitor following laparoscopic gastrectomy for locally advanced gastric cancer: a multicenter retrospective cohort study in China Hao CuiYongpu YangBo Wei Research Open access 05 September 2024 Article: 216
Immune microenvironmental heterogeneity according to tumor DNA methylation phenotypes in microsatellite instability-high colorectal cancers Jung Ho KimJiyun HongSangwoo Kim Research Open access 05 September 2024 Article: 215
Characterization of pre- and on-treatment soluble immune mediators and the tumor microenvironment in NSCLC patients receiving PD-1/L1 inhibitor monotherapy Daiki MurataKoichi AzumaTomoaki Hoshino Research Open access 05 September 2024 Article: 214
High proportion of PD-1 and CD39 positive CD8+ tissue resident T lymphocytes correlates with better clinical outcome in resected human oesophageal adenocarcinoma Samuel L. HillGessa SugiyartoTim Elliott Brief Report Open access 05 September 2024 Article: 213
Increasing monocytes after lung cancer surgery triggers the outgrowth of distant metastases, causing recurrence Yo KawaguchiKeigo OkamotoJun Hanaoka Research Open access 05 September 2024 Article: 212
Outcome of immune checkpoint inhibitor treatment in non-small cell lung cancer patients with interstitial lung abnormalities: clinical utility of subcategorizing interstitial lung abnormalities Ryota KikuchiYusuke WatanabeShinji Abe Research Open access 05 September 2024 Article: 211
Preclinical development of a novel CCR8/CTLA-4 bispecific antibody for cancer treatment by disrupting CTLA-4 signaling on CD8 T cells and specifically depleting tumor-resident Tregs Cuicui GuoXiaodong DaiXun Gui Research Open access 09 August 2024 Article: 210
NKG2D-bispecific enhances NK and CD8+ T cell antitumor immunity Aurelie HeraultJudy MakKevin B. Walsh Research Open access 08 August 2024 Article: 209
DNA hypo-methylation and expression of GBP4 induces T cell exhaustion in pancreatic cancer Yesiboli TasihengXuan LinChen Liu Research Open access 07 August 2024 Article: 208
Unlocking the potential of HHLA2: identifying functional immune infiltrating cells in the tumor microenvironment and predicting clinical outcomes in laryngeal squamous cell carcinoma Wenjing LiJianqing YouChangping Wu Research Open access 06 August 2024 Article: 207
Deciphering the interplay of HPV infection, MHC-II expression, and CXCL13+ CD4+ T cell activation in oropharyngeal cancer: implications for immunotherapy Shida YanXing ZhangMing Song Research Open access 06 August 2024 Article: 206