Adjuvant chemoradiotherapy plus pembrolizumab for locally advanced esophageal squamous cell carcinoma with high risk of recurrence following neoadjuvant chemoradiotherapy: a single-arm phase II study Jhe-Cyuan GuoTa-Chen HuangChih-Hung Hsu Research Open access 09 September 2024 Article: 230
Secretome and immune cell attraction analysis of head and neck cancers Tara MuijlwijkNiels E. WondergemRieneke van de Ven Research Open access 09 September 2024 Article: 229
Disruptions in antigen processing and presentation machinery on sarcoma Salvatore Lorenzo RenneLaura Sama’Ferdinando Carlo Maria Cananzi Research Open access 09 September 2024 Article: 228
Adding-on nivolumab to chemotherapy-stabilized patients is associated with improved survival in advanced pancreatic ductal adenocarcinoma Shih-Hung YangSung-Hsin KuoKun-Huei Yeh Research Open access 09 September 2024 Article: 227
Triple therapy boosts survival in NSCLC patients with brain metastases: a retrospective cohort study of chemotherapy, ICIs, and antiangiogenic agents Dingyi YangErha MunaiXiao-Dong Zhu Research Open access 06 September 2024 Article: 226
Impaired TGF-β signaling via AHNAK family mutations elicits an esophageal cancer subtype with sensitivities to genotoxic therapy and immunotherapy Zihang MaiKongjia LuoJianhua Fu Research Open access 05 September 2024 Article: 225
Correction to: Impact of fludarabine and treosulfan on ovarian tumor cells and mesothelin chimeric antigen receptor T cells Ibrahim El-SerafIsabella Micallef NilssonIsabelle Magalhaes Correction Open access 05 September 2024 Article: 224
Distribution characteristics of immune infiltration and lymphovascular invasion in patients with breast cancer skin recurrence Danyang ZhouMei LiRuoxi Hong Research Open access 05 September 2024 Article: 223
A comprehensive and longitudinal evaluation of the different populations of lymphoid and myeloid cells in the peripheral blood of patients treated with chemoradiotherapy for head and neck cancer Jens von der GrünMartina BrogliePanagiotis Balermpas Research Open access 05 September 2024 Article: 222
Oncolytic virotherapy augments self-maintaining natural killer cell line cytotoxicity against neuroblastoma Colin H. QuinnJanet R. JulsonElizabeth A. Beierle Research Open access 05 September 2024 Article: 221
Efficacy of durvalumab plus chemotherapy in advanced biliary duct cancer and biomarkers exploration Yunxin LuYin JinDongsheng Zhang Research Open access 05 September 2024 Article: 220
SAFFRON-104: a phase Ib/II study of sitravatinib alone or with tislelizumab in advanced hepatocellular carcinoma and gastric cancer/gastroesophageal junction cancer Jin LiYuxian BaiShukui Qin Research Open access 05 September 2024 Article: 219
Stat3-mediated Atg7 expression regulates anti-tumor immunity in mouse melanoma Sarah M. ZimmermanErin SuhGeorge P. Souroullas Brief Report Open access 05 September 2024 Article: 218
Immunogenomic features of radiologically distinctive nodules in multiple primary lung cancer Mei-Cheng ChenHao-Shuai YangYing Zhu Research Open access 05 September 2024 Article: 217
The short-term efficacy of neoadjuvant SOX versus SOX plus immune checkpoint inhibitor following laparoscopic gastrectomy for locally advanced gastric cancer: a multicenter retrospective cohort study in China Hao CuiYongpu YangBo Wei Research Open access 05 September 2024 Article: 216
Immune microenvironmental heterogeneity according to tumor DNA methylation phenotypes in microsatellite instability-high colorectal cancers Jung Ho KimJiyun HongSangwoo Kim Research Open access 05 September 2024 Article: 215
Characterization of pre- and on-treatment soluble immune mediators and the tumor microenvironment in NSCLC patients receiving PD-1/L1 inhibitor monotherapy Daiki MurataKoichi AzumaTomoaki Hoshino Research Open access 05 September 2024 Article: 214
High proportion of PD-1 and CD39 positive CD8+ tissue resident T lymphocytes correlates with better clinical outcome in resected human oesophageal adenocarcinoma Samuel L. HillGessa SugiyartoTim Elliott Brief Report Open access 05 September 2024 Article: 213
Increasing monocytes after lung cancer surgery triggers the outgrowth of distant metastases, causing recurrence Yo KawaguchiKeigo OkamotoJun Hanaoka Research Open access 05 September 2024 Article: 212
Outcome of immune checkpoint inhibitor treatment in non-small cell lung cancer patients with interstitial lung abnormalities: clinical utility of subcategorizing interstitial lung abnormalities Ryota KikuchiYusuke WatanabeShinji Abe Research Open access 05 September 2024 Article: 211
Preclinical development of a novel CCR8/CTLA-4 bispecific antibody for cancer treatment by disrupting CTLA-4 signaling on CD8 T cells and specifically depleting tumor-resident Tregs Cuicui GuoXiaodong DaiXun Gui Research Open access 09 August 2024 Article: 210
NKG2D-bispecific enhances NK and CD8+ T cell antitumor immunity Aurelie HeraultJudy MakKevin B. Walsh Research Open access 08 August 2024 Article: 209
DNA hypo-methylation and expression of GBP4 induces T cell exhaustion in pancreatic cancer Yesiboli TasihengXuan LinChen Liu Research Open access 07 August 2024 Article: 208
Unlocking the potential of HHLA2: identifying functional immune infiltrating cells in the tumor microenvironment and predicting clinical outcomes in laryngeal squamous cell carcinoma Wenjing LiJianqing YouChangping Wu Research Open access 06 August 2024 Article: 207
Deciphering the interplay of HPV infection, MHC-II expression, and CXCL13+ CD4+ T cell activation in oropharyngeal cancer: implications for immunotherapy Shida YanXing ZhangMing Song Research Open access 06 August 2024 Article: 206
Safety and clinical activity of JNJ-78306358, a human leukocyte antigen-G (HLA-G) x CD3 bispecific antibody, for the treatment of advanced stage solid tumors Ravit GevaMaria VieitoVictor Moreno Research Open access 06 August 2024 Article: 205
Targeting PI3K-gamma in myeloid driven tumour immune suppression: a systematic review and meta-analysis of the preclinical literature Haonan XuShannon Nicole RussellKeaton Ian Jones Review Open access 06 August 2024 Article: 204
Chimeric antigen receptor dendritic cells targeted delivery of a single tumoricidal factor for cancer immunotherapy Rong DuanPhilip MiltonZhenqiang Yao Research Open access 06 August 2024 Article: 203
Impact of the interval between neoadjuvant immunotherapy and surgery on prognosis in esophageal squamous cell carcinoma (ESCC): a real-world study Guozhen YangYutong HongXu Zhang Research Open access 06 August 2024 Article: 202
Hypofractionated radiotherapy plus PD-1 antibody and SOX chemotherapy as second-line therapy in metastatic pancreatic cancer: a single-arm, phase II clinical trial Qin WangFan TongJuan Du Research Open access 06 August 2024 Article: 201
Clinical features associated with immune checkpoint inhibitor nephritis: a single-center clinical case series Ramya MuddasaniNeel TalwarRavi Salgia Brief Report Open access 06 August 2024 Article: 200
Anlotinib reversed resistance to PD-1 inhibitors in recurrent and metastatic head and neck cancers: a real-world retrospective study Jianyun JiangBin WuZuguang Xia Research Open access 06 August 2024 Article: 199
CD27 signaling inhibits tumor growth and metastasis via CD8 + T cell-independent mechanisms in the B16-F10 melanoma model Eswara Rao PuppalaLong WuXuefang Cao Research Open access 06 August 2024 Article: 198
Genomic and transcriptomic profiles associated with response to eribulin and nivolumab combination in HER-2-negative metastatic breast cancer Changhee ParkKoung Jin SuhJee Hyun Kim Research Open access 06 August 2024 Article: 197
The expression of PD-L1 on tumor-derived exosomes enhances infiltration and anti-tumor activity of αCD3 × αPD-L1 bispecific antibody-armed T cells Jaewon ChoNara TaeHyun-Jeong Ko Research Open access 06 August 2024 Article: 196
Conversion of anti-tissue factor antibody sequences to chimeric antigen receptor and bi-specific T-cell engager format S. C. SaundersonJ. C. HalpinA. D. McLellan Research Open access 06 August 2024 Article: 195
First-line treatment with KN046, chemotherapy and palliative radiotherapy for advanced esophageal squamous cell carcinoma: an open-label, dose escalation, and dose expansion phase Ib trial Qi ZhaoXi SuSongbing Qin Research Open access 06 August 2024 Article: 194
Predicting recurrent glioblastoma clinical outcome to immune checkpoint inhibition and low-dose bevacizumab with tumor in situ fluid circulating tumor DNA analysis Guangzhong GuoZiyue ZhangXingyao Bu Research Open access 06 August 2024 Article: 193
TIGIT expression in renal cell carcinoma infiltrating T cells is variable and inversely correlated with PD-1 and LAG3 Oscar PeralesLucia JilaveanuDavid A. Schoenfeld Brief Report Open access 06 August 2024 Article: 192
GP100 expression is variable in intensity in melanoma Jacqueline E. MannNitzan HassonHarriet M. Kluger Brief Report Open access 06 August 2024 Article: 191
ALK5/VEGFR2 dual inhibitor TU2218 alone or in combination with immune checkpoint inhibitors enhances immune-mediated antitumor effects Nam-Hoon KimJihyun LeeHun-Taek Kim Research Open access 06 August 2024 Article: 190
Spatial cell interplay networks of regulatory T cells predict recurrence in patients with operable non-small cell lung cancer Siqi CaiGuanqun YangXiaorong Sun Research Open access 02 August 2024 Article: 189
Interleukin-7 expression by CAR-T cells improves CAR-T cell survival and efficacy in chordoma Huantong WuZhuofan XuZan Chen Research Open access 02 August 2024 Article: 188
Highlighting immune features of the tumor ecosystem and prognostic value of Tfh and Th17 cell infiltration in head and neck squamous cell carcinoma by single-cell RNA-seq Yan TianChao LiuShikai Wu Research Open access 02 August 2024 Article: 187
Negative association of steroids with immunotherapy efficacy in a multi-tumor cohort: time and dose-dependent Víctor AlbarránPatricia GuerreroPablo Gajate Research Open access 02 August 2024 Article: 186
Efficacy of adjuvant immune checkpoint inhibitors pembrolizumab or nivolumab in melanoma patients ≥ 75 years: results of a real-world cohort including 456 patients A. GawazI. WolffA. Forschner Research Open access 05 July 2024 Article: 185
Correction to: New CEACAM-targeting 2A3 single-domain antibody-based chimeric antigen receptor T-cells produce anticancer effects in vitro and in vivo Iga JancewiczMagdalena ŚmiechPawel Wisniewski Correction Open access 05 July 2024 Article: 184
Correction to: The radiomics nomogram predicts the prognosis of pancreatic cancer patients with hepatic metastasis after chemoimmunotherapy Wenxin LuGuangyu WuLiwei Wang Correction Open access 05 July 2024 Article: 183
Long-term survivals of immune checkpoint inhibitors as neoadjuvant and adjuvant therapy in dMMR/MSI-H colorectal and gastric cancers Zhenghang WangSiyuan ChengJian Li Research Open access 05 July 2024 Article: 182
In vitro T cell responses to PD-1 blockade are reduced by IFN-α but do not predict therapy response in melanoma patients Laura M. TimmermanLobke C. M. Hensenthe UNICIT consortium Research Open access 05 July 2024 Article: 181