1. Metformin for obese, insulin-treated diabetic patients: improvement in glycaemic control and reduction of metabolic risk factors

   • D. Giugliano
   • A. Quatraro
   • F. D'Onofrio

   Originals Pages: 107 - 112

2. Comparative effects of felodipine, nitrendipine and nifedipine in healthy subjects: concentration-effect relationships of racemic drugs and enantiomers

   • P. A. Soons
   • A. F. Cohen
   • D. D. Breimer

   Originals Pages: 113 - 120

3. Serotonin-induced platelet aggregation predicts the antihypertensive response to serotonin receptor antagonists

   • G. Gleerup
   • B. Persson
   • K. Winther

   Originals Pages: 121 - 125

4. Beta-adrenoceptor blockade potentiates acute exercise-induced release of atrial natriuretic peptide by increasing atrial diameter in normotensive healthy subjects

   • I. Berlin
   • Ph. Lechat
   • A. J. Puech

   Originals Pages: 127 - 133

5. Savoxepine: striatal dopamine-D₂ receptor occupancy in human volunteers measured using positron emission tomography (PET)

   • K. L. Leenders
   • A. Antonini
   • P. C. Waldmeier

   Originals Pages: 135 - 140

6. Benzodiazepine prescribing patterns in a high-prescribing scandinavian community

   • A. Ekedahl
   • J. Lidbeck
   • A. Melander

   Originals Pages: 141 - 146

7. Identification of factors regulating thiopurine methyltransferase activity in a Norwegian population

   • B. Klemetsdal
   • B. Straume
   • J. Aarbakke

   Originals Pages: 147 - 152

8. Evaluation of a new spacer device for drug inhalation

   • B. Stenius-Aarniala
   • K. Kiviranta
   • H. Poppius

   Originals Pages: 153 - 155

9. Variation in the binding affinity of warfarin and phenprocoumon to human serum albumin in relation to surgery

   • H. Vorum
   • H. R. I. Jørgensen
   • R. Brodersen

   Originals Pages: 157 - 162

10. Stereoselective pharmacokinetics of oral felodipine and nitrendipine in healthy subjects: correlation with nifedipine pharmacokinetics

    • P. A. Soons
    • T. M. T. Mulders
    • D. D. Breimer

    Originals Pages: 163 - 169

11. The effect of oxprenolol dosage time on its pharmacokinetics and haemodynamic effects during exercise in man

    • R. Koopmans
    • B. Oosterhuis
    • C. J. van Boxtel

    Originals Pages: 171 - 176

12. Pharmacodynamic model of the haemodynamic effects of pinacidil in normotensive volunteers

    • P. Girard
    • J. L. Saumet
    • J. P. Boissel

    Originals Pages: 177 - 182

13. The effect of haemodialysis on the pharmacokinetics of perindoprilat after long-term perindopril

    • A. Guérin
    • G. Resplandy
    • G. London

    Originals Pages: 183 - 187

14. Steady-state pharmacokinetics of methadone in opioid addicts

    • K. Wolff
    • A. W. M. Hay
    • R. Calvert

    Originals Pages: 189 - 194

15. The relation between type of renal disease and renal drug clearance in children

    • C. M. Paap
    • M. C. Nahata

    Short Communications Pages: 195 - 197

16. The effect of yohimbine on sympathetic responsiveness in essential hypertension

    • C. Damase-Michel
    • M. A. Tran
    • P. Montastruc

    Short Communications Pages: 199 - 201

17. Effect of chlormethiazole on hepatic monooxygenases activity in vivo

    • H. Mönig
    • D. J. Back
    • H. M. Schulte

    Short Communications Pages: 203 - 204

18. Lack of interaction of ketoprofen with warfarin

    • C. Mieszczak
    • K. Winther

    Short Communications Pages: 205 - 206

19. Lack of effect of amoxycillin on the absorption of ofloxacin

    • G. Paintaud
    • G. Alván
    • I. Nilsson-Ehle

    Short Communications Pages: 207 - 209

20. Announcements

    Announcement Pages: 210 - 210