1. The experimental imperative

   • Jack Bergman
   • Jonathan L. Katz
   • Klaus A. Miczek

   Introduction Pages: 249 - 250

2. Continuing implications of the early evidence against the drive-reduction hypothesis of the behavioral effects of drugs

   • Donald E. McMillan
   • Jonathan L. Katz

   Review Pages: 251 - 264

3. Behavioral effects of cocaine and dopaminergic strategies for preclinical medication development

   • Donna M. Platt
   • James K. Rowlett
   • Roger D. Spealman

   Review Pages: 265 - 282

4. Effects of cocaine under concurrent fixed ratio schedules of food and IV drug availability: a novel choice procedure in monkeys

   • Carol A. Paronis
   • Maciej Gasior
   • Jack Bergman

   Original Investigation Pages: 283 - 291

5. Cocaine- and food-maintained responding under a multiple schedule in rhesus monkeys: environmental context and the effects of a dopamine antagonist

   • Michael A. Nader
   • Rachna S. Sinnott
   • Drake Morgan

   Original Investigation Pages: 292 - 301

6. Role of dose order in the development of tolerance to effects of cocaine on schedule-controlled behavior in pigeons

   • Michelle L. Miller
   • Marc N. Branch

   Original Investigation Pages: 302 - 309

7. Improved multiparameter models of drug effects on response rate under multiple variable interval schedules: evidence from rat studies

   • Fernando A. González

   Review Pages: 310 - 318

8. The generalized matching law as a predictor of choice between cocaine and food in rhesus monkeys

   • Karen G. Anderson
   • Andrew J. Velkey
   • William L. Woolverton

   Original Investigation Pages: 319 - 326

9. Second-order schedules of drug self-administration in animals

   • Charles W. Schindler
   • Leigh V. Panlilio
   • Steven R. Goldberg

   Review Pages: 327 - 344

10. Observing responses maintained by stimuli associated with cocaine or remifentanil reinforcement in rhesus monkeys

    • J. Woods
    • G. Winger

    Original Investigation Pages: 345 - 351

11. Functional imaging and neurochemical correlates of stimulant self-administration in primates

    • Leonard L. Howell
    • Kristin M. Wilcox

    Review Pages: 352 - 361

12. The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry

    • T. Robbins

    Review Pages: 362 - 380

13. The effects of psychotomimetics and psychomotor stimulants on two schedules promoting response switching in the rat

    • John Evenden

    Original Investigation Pages: 381 - 390

14. Effect of pentobarbital, d-amphetamine, and nicotine on two models of sustained attention in pigeons

    • Charlotte A. Lemmonds
    • Keith D. Williams
    • Galen R. Wenger

    Original Investigation Pages: 391 - 398

15. Separate and combined effects of marijuana and alcohol on mood, equilibrium and simulated driving

    • Anthony Liguori
    • Catherine P. Gatto
    • David B. Jarrett

    Original Investigation Pages: 399 - 405

16. Determinants of the behavioral effects of opioids and their antagonists: contributions of the Laboratory of Psychobiology

    • J. Woods
    • C. France

    Review Pages: 406 - 411

17. Kappa opioid antagonist effects of the novel kappa antagonist 5′-guanidinonaltrindole (GNTI) in an assay of schedule-controlled behavior in rhesus monkeys

    • Stevens S. Negus
    • Nancy K. Mello
    • Philip S. Portoghese

    Original Investigation Pages: 412 - 419

18. Antinociceptive effects of the selective delta opioid agonist SNC80 alone and in combination with mu opioids in the squirrel monkey titration procedure

    • Linda Dykstra
    • Arthur L. Granger
    • Kenner C. Rice

    Original Investigation Pages: 420 - 429

19. Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats

    • Lisa A. Teather
    • Jane E. Magnusson
    • Richard J. Wurtman

    Original Investigation Pages: 430 - 433

20. Social and neural determinants of aggressive behavior: pharmacotherapeutic targets at serotonin, dopamine and γ-aminobutyric acid systems

    • Klaus A. Miczek
    • Eric W. Fish
    • Rosa M. de Almeida

    Review Pages: 434 - 458

21. Aggressive behavior as a reinforcer in mice: activation by allopregnanolone

    • Eric W. Fish
    • Joseph F. De Bold
    • Klaus A. Miczek

    Original Investigation Pages: 459 - 466

22. On serotonin and experimental anxiety

    • Frederico G. Graeff

    Review Pages: 467 - 476

23. Relation between discriminative and reinforcing effects of midazolam, pentobarbital, chlordiazepoxide, zolpidem, and imidazenil in baboons

    • Nancy A. Ator

    Original Investigation Pages: 477 - 487

24. Some contextual and historical determinants of the effects of chlordiazepoxide on punished responding of rats

    • Jeffrey M. Witkin

    Original Investigation Pages: 488 - 494

25. Potential antidepressant properties of pramipexole detected in locomotor and operant behavioral investigations in mice

    • Erich Lehr

    Original Investigation Pages: 495 - 500