1. Harriet de wit

   • H deWit

   Editorial Pages: 1 - 1

2. The scientific case that nicotine is addictive

   • I. P. Stolerman
   • M. J. Jarvis

   Review Pages: 2 - 10

3. The addictive role of nicotine in tobacco use

   • J. E. Henningfield
   • S. J. Heishman

   Commentary Pages: 11 - 13

4. Comments on nicotine addiction

   • S. Shiffman

   Commentary Pages: 14 - 15

5. Reply to stolerman and jarvis

   • J. H. Robinson
   • W. S. Pritchard

   Commentary Pages: 16 - 17

6. Commentary

   • M. E. Jarvik

   ReviewPaper Pages: 18 - 20

7. Commentary on the nicotine IS/IS not addictive debate

   • J. H. Jaffe

   Commentary Pages: 21 - 22

8. Opioid operant self-administration, analgesia, stimulation and respiratory depression inμ-deficient mice

   • Gregory I. Elmer
   • Jeanne O. Pieper
   • Frank R. George

   Original Investigation Pages: 23 - 31

9. Conditioned ultrasonic distress vocalizations in adult male rats as a behavioural paradigm for screening anti-panic drugs

   • H. E. Molewijk
   • A. M. van der Poel
   • B. Olivier

   Original Investigation Pages: 32 - 40

10. 8-OH-DPAT disruption of prepulse inhibition in rats: reversal with (+)WAY 100,135 and localization of site of action

    • THomas A. Sipes
    • Mark A. Geyer

    Original Investigation Pages: 41 - 48

11. Development and reversal of sensitization to amphetamine-induced hypophagia: role of temporal, pharmacological, and behavioral variables

    • David L. Wolgin

    Original Investigation Pages: 49 - 54

12. Dopamine D₂ receptor blockade in vivo with the novel antipsychotics risperidone and remoxipride — an¹²³I-IBZM single photon emission tomography (SPET) study

    • G. F. Busatto
    • L. S. Pilowsky
    • N. P. L. G. Verhoeff

    Original Investigation Pages: 55 - 61

13. Chromosomal mapping of loci influencing sensitivity to cocaine-induced seizures in BXD recombinant inbred strains of mice

    • Lucinda L. Miner
    • Rodney J. Marley

    Original Investigation Pages: 62 - 66

14. In vivo pharmacological effects of dihydro-β-erythroidine, a nicotinic antagonist, in mice

    • M. I. Damaj
    • S. P. Welch
    • B. R. Martin

    Original Investigation Pages: 67 - 73

15. Neuroleptic-induced vacuous chewing movements in rodents: incidence and effects of long-term increases in haloperidol dose

    • Michael F. Egan
    • Richard Jed Wyatt
    • Joel E. Kleinman

    Original Investigation Pages: 74 - 81

16. Analysis of the effects of intra-accumbens SKF-38393 and LY-171555 upon the behavioural satiety sequence

    • Gavin D. Phillips
    • Simon R. Howes
    • Trevor Robbins

    Original Investigation Pages: 82 - 90

17. Effects of indorenate on food intake: a comparison with fenfluramine and amphetamine

    • D. N. Velázquez Martínez
    • M. Valencia Flores
    • J. E. Villarreal

    Original Investigation Pages: 91 - 101

18. Temporal factors in the effect of restraint stress on morphine-induced behavioral sensitization in the rat

    • Yavin Shaham
    • Jane Stewart
    • John E. Kelsey

    Original Investigation Pages: 102 - 109

19. Nicotine intake in smokers increases following a single dose of haloperidol

    • S. Dawe
    • J. A. Gray
    • C. Gerda

    Original Investigation Pages: 110 - 115

20. Social deprivation enhances the vulnerability of male Wistar rats to stressor- and amphetamine-induced behavioral sensitization

    • S. H. Ahmed
    • L. Stinus
    • M. Cador

    Original Investigation Pages: 116 - 124