Draft guidelines on mutagenicity testing of new drugs issued by the CPMP Morrell H. DraperJohn P. Griffin OriginalPaper Pages: 9 - 19
Evaluating the mutagenic potential of chemicals the minimal battery and extrapolation problems F. H. Sobels OriginalPaper Pages: 21 - 30
Mutagenicity testing with Salmonella microsome test H. GreimW. GöggelmannT. Wolff OriginalPaper Pages: 31 - 40
Appreciation of the value of different bacterial test systems for detecting and for ranking chemical mutagens G. R. MohnJ. Ellenberger OriginalPaper Pages: 45 - 60
Mutagenicity test systems for the detection of chromosome aberrations in vivo B. E. MatterT. Tsuchimoto OriginalPaper Pages: 89 - 98
Unscheduled DNA synthesis in the testis, a secondary test for the evaluation of chemical mutagens G. Zbinden OriginalPaper Pages: 139 - 149
Inductest and spermatest in genetic toxicology testing Maurice HofnungNicole Weill OriginalPaper Pages: 159 - 169
Covalent binding of drug metabolites to DNA — a tool of predictive value? Hermann M. BoltReinhold J. Laib OriginalPaper Pages: 171 - 180
Metabolic activation of drugs in mutagenicity tests in vitro M. B. Roberfroid OriginalPaper Pages: 181 - 193
International programme for the evaluation of short-term tests for carcinogenicity I. F. H. PurchaseF. J. de Serres OriginalPaper Pages: 195 - 198