1. Introduction

   • A. Podjarny

   Multi-author Review Pages: 735 - 736

2. All in the family: aldose reductase and closely related aldo-keto reductases

   • J. M. Petrash

   Multi-author Review Pages: 737 - 749

3. Aldose reductase structures: implications for mechanism and inhibition

   • O. El-Kabbani
   • F. Ruiz
   • R. P.-T. Chung

   Multi-author Review Pages: 750 - 762

4. Subatomic and atomic crystallographic studies of aldose reductase: implications for inhibitor binding

   • A. Podjarny
   • R. E. Cachau
   • A. Joachimiak

   Multi-author Review Pages: 763 - 773

5. Ultra-high-resolution X-ray structure of proteins

   • C. Lecomte
   • B. Guillot
   • C. Jelsch

   Multi-author Review Pages: 774 - 782

6. Strategies for the design of inhibitors of aldose reductase, an enzyme showing pronounced induced-fit adaptations

   • G. Klebe
   • O. Krämer
   • C. Sotriffer

   Multi-author Review Pages: 783 - 793

7. The never-ending story of peptide O-xylosyltransferase

   • I. B. H. Wilson

   Review Pages: 794 - 809

8. Where, when and how much: regulation of myelin proteolipid protein gene expression

   • P. A. Wight
   • A. Dobretsova

   Review Pages: 810 - 821

9. The common and distinct target genes of the p53 family transcription factors

   • K. Harms
   • S. Nozell
   • X. Chen

   Review Pages: 822 - 842

10. Snake venom thrombin-like enzymes: from reptilase to now

    • H. C. Castro
    • R. B. Zingali
    • C. R. Rodrigues

    Review Pages: 843 - 856

11. Caffeine as a psychomotor stimulant: mechanism of action

    • G. Fisone
    • A. Borgkvist
    • A. Usiello

    Review Pages: 857 - 872

12. Novel aspects and new roles for the serine protease plasmin

    • T. Syrovets
    • Th. Simmet

    Review Pages: 873 - 885

13. Neurobiology and neuroimmunology of Tourette’s syndrome: an update

    • P. J. Hoekstra
    • G. M. Anderson
    • R. B. Minderaa

    Review Pages: 886 - 898

14. Hedgehog signaling in vertebrate eye development: a growing puzzle

    • M. A. Amato
    • S. Boy
    • M. Perron

    Review Pages: 899 - 910

15. MAGUKs in synapse assembly and function: an emerging view

    • J. M. Montgomery
    • P. L. Zamorano
    • C. C. Garner

    Review Pages: 911 - 929

16. Prediction of protein function and pathways in the genome era

    • T. Gabaldón
    • M. A. Huynen

    Review Pages: 930 - 944

17. Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain

    • M. Valenti
    • D. Viganò
    • V. Di Marzo

    Research Article Pages: 945 - 950

18. Helix H1 of the prion protein is rather stable against environmental perturbations: molecular dynamics of mutation and deletion variants of PrP(90–231)

    • S. Santini
    • P. Derreumaux

    Research Article Pages: 951 - 960

19. Involvement of penaeidins in defense reactions of the shrimp Litopenaeus stylirostris to a pathogenic vibrio

    • M. Muňoz
    • F. Vandenbulcke
    • E. Bachère

    Research Article Pages: 961 - 972

20. Gene expression profiles in the cellular response to a multinuclear platinum complexe

    • L. Gatti
    • G. L. Beretta
    • P. Perego

    Research Article Pages: 973 - 981

21. Investigation of the effects of copper ions on protein aggregation using a model system

    • C. Capanni
    • N. Taddei
    • G. Ramponi

    Research Article Pages: 982 - 991

22. Human and rodent type 1 11β-hydroxysteroid dehydrogenases are 7β-hydroxycholesterol dehydrogenases involved in oxysterol metabolism

    • M. Hult
    • B. Elleby
    • U. Oppermann

    Research Article Pages: 992 - 999