DNA damage repair in glioblastoma: current perspectives on its role in tumour progression, treatment resistance and PIKKing potential therapeutic targets Mathew LozinskiNikola A. BowdenPaul A. Tooney Review 31 May 2021 Pages: 961 - 981
The impact of mitochondria on cancer treatment resistance Michelle van der MerweGustav van NiekerkAnna-Mart Engelbrecht Review 09 July 2021 Pages: 983 - 995
Histone deacetylase (HDAC) 9: versatile biological functions and emerging roles in human cancer Chun YangStéphane CroteauPierre Hardy Review Open access 27 July 2021 Pages: 997 - 1017
Loss of ARID1A expression promotes lung adenocarcinoma metastasis and predicts a poor prognosis Dantong SunYan ZhuHelei Hou Original Article 09 June 2021 Pages: 1019 - 1034
Combined inhibition of AURKA and HSF1 suppresses proliferation and promotes apoptosis in hepatocellular carcinoma by activating endoplasmic reticulum stress Zetian ShenLi YinXia He Original Article 26 June 2021 Pages: 1035 - 1049
Cystatin F acts as a mediator of immune suppression in glioblastoma Emanuela SenjorMilica Perišić NanutJanko Kos Original Article 29 June 2021 Pages: 1051 - 1063
RNA sequencing and functional studies of patient-derived cells reveal that neurexin-1 and regulators of this pathway are associated with poor outcomes in Ewing sarcoma Elizabeth Ann RoundhillMariona Chicon-BoschSusan Ann Burchill Original Article Open access 17 August 2021 Pages: 1065 - 1085
Blocking MMP-12-modulated epithelial-mesenchymal transition by repurposing penfluridol restrains lung adenocarcinoma metastasis via uPA/uPAR/TGF-β/Akt pathway Wen-Yueh HungWei-Jiunn LeeMing-Hsien Chien Original Article 28 July 2021 Pages: 1087 - 1103
Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia Jean Carlos Lipreri da SilvaJuan Luiz Coelho-SilvaJoão Agostinho Machado-Neto Original Article 01 July 2021 Pages: 1105 - 1117
Bile acids increase intestinal marker expression via the FXR/SNAI2/miR-1 axis in the stomach Na WangSiran WuYongquan Shi Original Article Open access 12 September 2021 Pages: 1119 - 1131
EMP2 induces cytostasis and apoptosis via the TGFβ/SMAD/SP1 axis and recruitment of P2RX7 in urinary bladder urothelial carcinoma Chien-Feng LiTi-Chun ChanYow-Ling Shiue Original Article 02 August 2021 Pages: 1133 - 1150
Mild chronic hypoxia-induced HIF-2α interacts with c-MYC through competition with HIF-1α to induce hepatocellular carcinoma cell proliferation Han MuGe YuChangfu Liu Original Article 02 August 2021 Pages: 1151 - 1166
Hypoxia-induced ROS promotes mitochondrial fission and cisplatin chemosensitivity via HIF-1α/Mff regulation in head and neck squamous cell carcinoma Kun WuYuan-yuan MaoYan Li Original Article 30 August 2021 Pages: 1167 - 1181
YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models Lukas Clemens BöckelmannTheresa FelixUdo Schumacher Original Article Open access 25 August 2021 Pages: 1183 - 1195
A phospho-proteomic study of cetuximab resistance in KRAS/NRAS/BRAFV600 wild-type colorectal cancer Alexandros GeorgiouAdam StewartUdai Banerji Short Communication Open access 30 August 2021 Pages: 1197 - 1206
Retraction Note: Human bone marrow-derived mesenchymal stem cell-secreted exosomes overexpressing microRNA-34a ameliorate glioblastoma development via down-regulating MYCN Bin WangZhong-Hua WuMing Li Retraction Note 19 August 2021 Pages: 1207 - 1207