Collections and calls for papers

Studies have shown that cancer-associated fibroblasts (CAFs) play a crucial role in the tumor microenvironment. Despite numerous research efforts in this area, targeting CAFs remains challenging. In this col...

Survival of the fittest! Sadly this also applies to cancer cells. In the early phase of cancer, (epi)genetic mutations in initiated cells may be selected for their ability to exploit cell competition to elim...

Circulating tumor DNA is a promising liquid biopsy marker for cancer diagnosis, treatment selection and clinical follow-up of cancer patients. This series focuses on ongoing developments in circulating tumor...

Immunotherapy with promising and lasting clinical responses provides a new breakthrough treatment modality for a variety of refractory cancers and malignancies. However, a large proportion of patients do not...

With the advancement of sequencing technologies, whole genome sequence information can be obtained robustly in a fairly short time and at low cost. Yet, currently there is often a lack of connection of genom...

The total chromosome number of most of our somatic cells has to be faithfully maintained. Either gain or loss of chromosome leading to a sum that is not an exact multiple of the haploid number would result i...

Tumor immunology is to gain insights in the interaction between the immune system and tumors, which is crucial for our understanding on the mechanisms of both tumor elimination and tumor escaping. Exploiting...