1. Focus on antimicrobial use in the era of increasing antimicrobial resistance in ICU

   • Matteo Bassetti
   • Garyphallia Poulakou
   • Jean-François Timsit

   Focus Editorial 04 April 2016 Pages: 955 - 958

2. Focus on acute kidney injury and fluids

   • Miet Schetz
   • Michael Darmon
   • Anders Perner

   Focus Editorial 17 March 2016 Pages: 959 - 961

3. Comfort and patient-centred care without excessive sedation: the eCASH concept

   • Jean-Louis Vincent
   • Yahya Shehabi
   • Jukka Takala

   Review Open access 13 April 2016 Pages: 962 - 971

   

4. Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals

   • Julia Harris
   • Anne-Sylvie Ramelet
   • Erwin Ista

   Guidelines Open access 15 April 2016 Pages: 972 - 986

   

5. Effect of ICU strain on timing of limitations in life-sustaining therapy and on death

   • May Hua
   • Scott D. Halpern
   • Hannah Wunsch

   Original 09 February 2016 Pages: 987 - 994

   

6. CAESAR: a new tool to assess relatives’ experience of dying and death in the ICU

   • Nancy Kentish-Barnes
   • Valérie Seegers
   • Elie Azoulay

   Original 07 March 2016 Pages: 995 - 1002

   

7. Guidelines for the withdrawal of life-sustaining measures

   • James Downar
   • Jesse W. Delaney
   • Lisa Kenny

   Original 08 April 2016 Pages: 1003 - 1017

   

8. Effect of probiotics on the incidence of ventilator-associated pneumonia in critically ill patients: a randomized controlled multicenter trial

   • Juan Zeng
   • Chun-Ting Wang
   • Yu-Ping Wang

   Original 04 April 2016 Pages: 1018 - 1028

   

9. Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients: a retrospective observational study

   • Liesbet De Bus
   • Wouter Denys
   • Pieter O. Depuydt

   Original 30 March 2016 Pages: 1029 - 1039

   

10. Does increased ICU strain prompt clinicians to communicate with families about end-of-life issues earlier?

    • Renee D. Stapleton
    • Dominique D. Benoit

    Editorial 20 April 2016 Pages: 1040 - 1042

11. Addressing uncertainty: what is the role of consensus in end-of-life care?

    • Ann C. Long
    • Peter E. Spronk
    • Charles L. Sprung

    Editorial 07 April 2016 Pages: 1043 - 1044

12. Research in Latin America: opportunities and challenges

    • Elisa Estenssoro
    • Gilberto Friedman
    • Glenn Hernández

    Editorial 04 April 2016 Pages: 1045 - 1047

    

13. Early goal-directed therapy: do we have a definitive answer?

    • Daniel De Backer
    • Jean-Louis Vincent

    Editorial 07 March 2016 Pages: 1048 - 1050

14. Is this critically ill patient immunocompromised?

    • Frédéric Pène
    • Peter Pickkers
    • Richard S. Hotchkiss

    WHAT’S NEW IN INTENSIVE CARE 02 December 2015 Pages: 1051 - 1054

    

15. What’s new in myocarditis?

    • Charles-Edouard Luyt
    • Guillaume Hékimian
    • Fredric Ginsberg

    What's New in Intensive Care 14 August 2015 Pages: 1055 - 1057

    

16. Does this ventilated patient have asynchronies? Recognizing reverse triggering and entrainment at the bedside

    • Gastón Murias
    • Candelaria de Haro
    • Lluis Blanch

    What's New in Intensive Care 16 December 2015 Pages: 1058 - 1061

    

17. What’s new in the diagnostic criteria of disseminated intravascular coagulation?

    • Satoshi Gando
    • Ferhat Meziani
    • Marcel Levi

    What's New in Intensive Care 08 February 2016 Pages: 1062 - 1064

    

18. Choice architecture in code status discussions with terminally ill patients and their families

    • George L. Anesi
    • Scott D. Halpern

    What's New in Intensive Care 07 March 2016 Pages: 1065 - 1067

19. Understanding abdominal compartment syndrome

    • J. J. De Waele
    • I. De laet
    • M. L. N. G. Malbrain

    Understanding the Disease 12 October 2015 Pages: 1068 - 1070

20. Cardiac luxation in ICU after coughing effort following right pneumonectomy

    • Jean-Michel Maury
    • Arnaud Pasquer
    • François Tronc

    Imaging in Intensive Care Medicine 10 November 2015 Pages: 1071 - 1072

    

21. Acute bioprosthetic mitral valve thrombosis

    • Ronson Madathil
    • Kei Togashi
    • Joshua L. Hermsen

    Imaging in Intensive Care Medicine 19 November 2015 Pages: 1073 - 1074

    

22. Emphysematous pancreatitis

    • Seiko Hamada
    • Nobuaki Shime

    Imaging in Intensive Care Medicine 22 December 2015 Pages: 1075 - 1075

    

23. Anne Marie’s Christmas

    • Ashok P. Sarnaik
    • Anne Marie Campbell
    • Rosemary Campbell

    From the Inside 19 November 2015 Pages: 1076 - 1077

24. Transcutaneous CO₂ monitoring: a new tool to identify spontaneous breathing trial failure during weaning from mechanical ventilation. A pilot cohort study

    • Juliana Henao-Brasseur
    • Jérôme Bedel
    • Benjamin Planquette

    Letter 10 February 2016 Pages: 1078 - 1079

    

25. Risk of oxalate nephropathy with the use of cyanide antidote hydroxocobalamin in critically ill burn patients

    • Matthieu Legrand
    • Thibault Michel
    • for the PRONOBURN Study Group

    Letter 18 February 2016 Pages: 1080 - 1081

    

26. PF4-heparin antibodies during ECMO: incidence, course, and outcomes

    • Florent Laverdure
    • Virginie Louvain-Quintard
    • François Stéphan

    Letter 22 February 2016 Pages: 1082 - 1083

27. Effects of magnesium supplementation on the incidence of acute kidney injury in critically ill patients presenting with hypomagnesemia

    • Elisa Baldessar Barbosa
    • Cristiane Damiani Tomasi
    • Felipe Dal-Pizzol

    Letter 29 February 2016 Pages: 1084 - 1085

28. BIS monitoring in sedated, mechanically ventilated patients: right tool in the wrong patients? A meta-analysis

    • Renan Goulart Finger
    • Cassio Mallmann
    • Wagner Luis Nedel

    Letter 29 February 2016 Pages: 1086 - 1087

    

29. Electrical impedance tomography to monitor lung sampling during broncho-alveolar lavage

    • Domenico Luca Grieco
    • Benedetta Mura
    • Massimo Antonelli

    Letter 15 March 2016 Pages: 1088 - 1089

    

30. Effects of chest physiotherapy by expiratory flow increase on secretion removal and lung mechanics in ventilated patients: a randomized crossover study

    • Anne Freynet
    • Guillaume Gobaille
    • Alexandre Ouattara

    Letter 31 March 2016 Pages: 1090 - 1091

    

31. Any trial can (almost) kill a good technique

    • Martin C. J. Kneyber
    • Dick G. Markhorst

    Correspondence 29 January 2016 Pages: 1092 - 1093

    

32. ICU-acquired candidemia within SDD: low incidence in a 20-year longitudinal database

    • Sophie H. Buitinck
    • Durk F. Zandstra
    • Peter H. J. van der Voort

    Correspondence 03 February 2016 Pages: 1094 - 1095

33. Aspirin may improve outcome in sepsis by augmentation of the inflammatory response

    • H. D. Kiers
    • M. Kox
    • P. Pickkers

    Correspondence 04 April 2016 Pages: 1096 - 1096

34. Role of aspirin in patients with septic shock: a complex and intriguing relationship

    • Marco Falcone
    • Mario Venditti
    • Francesco Violi

    Correspondence 31 March 2016 Pages: 1097 - 1097

35. Efficiency and safety of apnea test process under extracorporeal membrane oxygenation: the most effective method remains questionable

    • B. Champigneulle
    • V. Chhor
    • D. Journois

    Correspondence 16 February 2016 Pages: 1098 - 1099

    

36. Internal reporting system: we must look behind the curtain

    • Bjoern Zante
    • Roland Ernst Dietler
    • Jukka Takala

    Correspondence 31 March 2016 Pages: 1100 - 1100

37. Daily sedation interruption in children warrants further study

    • Jerry J. Zimmerman
    • R. Scott Watson
    • E. Wesley Ely

    Correspondence 31 March 2016 Pages: 1101 - 1102

38. Striving for an effective but parsimonious use of sedation in pediatric intensive care

    • Nienke J. Vet
    • Saskia N. de Wildt
    • Matthijs de Hoog

    Correspondence 31 March 2016 Pages: 1103 - 1104

39. Erratum to: Authors’ response: Origin of the 24-h rest arm

    • Franco Laghi
    • Nausica D’Alfonso
    • Martin J. Tobin

    Erratum 31 March 2016 Pages: 1105 - 1105

40. Erratum to: Is this critically ill patient immunocompromised?

    • Frédéric Pène
    • Peter Pickkers
    • Richard S. Hotchkiss

    Erratum 28 January 2016 Pages: 1106 - 1106