1. Basic, clinical, and epidemiological studies of progressive multifocal leukoencephalopathy: Implications for therapy

   • Jeymohan Joseph
   • Eugene O. Major

   Guest Editorial Pages: 1 - 2

2. An overview: Human polyomavirus JC virus and its associated disorders

   • Mahmut Safak
   • Kamel Khalili

   OriginalPaper Pages: 3 - 9

3. JC virus agnoprotein colocalizes with tubulin

   • Shuichi Endo
   • Yuki Okada
   • Hirofumi Sawa

   OriginalPaper Pages: 10 - 14

4. T′ proteins influence JC virus biology

   • Richard J. Frisque
   • Brigitte Bollag
   • Lisa H. Kilpatrick

   OriginalPaper Pages: 15 - 20

5. Analysis of DNA-binding activity of the JC virus minor capsid protein VP2

   • Yih-Leh Huang
   • Meilin Wang
   • Deching Chang

   OriginalPaper Pages: 21 - 24

6. Inflammatory reaction in progressive multifocal leukoencephalopathy: Harmful or beneficial?

   • Renaud A. Du Pasquier
   • Igor J. Koralnik

   OriginalPaper Pages: 25 - 31

7. Early events in the life cycle of JC virus as potential therapeutic targets for the treatment of progressive multifocal leukoencephalopathy

   • S. Baum
   • A. Ashok
   • Walter J. Atwood

   OriginalPaper Pages: 32 - 37

8. Progressive multifocal leukoencephalopathy in acquired immunodeficiency syndrome: Explaining the high incidence and disproportionate frequency of the illness relative to other immunosuppressive conditions

   • Joseph R. Berger

   OriginalPaper Pages: 38 - 41

9. Analysis of JC virus genotype distribution and transcriptional control region rearrangements in human immunodeficiency virus-positive progressive multifocal leukoencephalopathy patients with and without highly active antiretroviral treatment

   • Pasquale Ferrante
   • Serena Delbue
   • Paola Cinque

   OriginalPaper Pages: 42 - 46

10. Clinical epidemiology and survival of progressive multifocal leukoencephalopathy in the era of highly active antiretroviral therapy: Data from the Italian Registry Investigative Neuro AIDS (IRINA)

    • Andrea Antinori
    • Antonella Cingolani
    • Italian Registry Investigative Neuro AIDS (IRINA) Study Group

    OriginalPaper Pages: 47 - 53

11. Role of the environment in the transmission of JC virus

    • Sílvia Bofill-Mas
    • Rosina Girones

    OriginalPaper Pages: 54 - 58

12. Low prevalence of progressive multifocal leukoencephalopathy in India and Africa: Is there a biological explanation?

    • S. K. Shankar
    • P. Satishchandra
    • A. Nath

    OriginalPaper Pages: 59 - 67

13. Challenges for clinical trials to treat progressive multifocal leukoencephalopathy

    • David B. Clifford

    OriginalPaper Pages: 68 - 72

14. The effect of highly active antiretroviral therapy-induced immune reconstitution on development and outcome of progressive multifocal leukoencephalopathy: Study of 43 cases with review of the literature

    • Paola Cinque
    • Simona Bossolasco
    • Adriano Lazzarin

    OriginalPaper Pages: 73 - 80

15. Association of human polyomavirus JC with peripheral blood of immunoimpaired and healthy individuals

    • Kristina Dörries
    • Silviu Sbiera
    • Rüdiger Dörries

    OriginalPaper Pages: 81 - 87

16. The evolving face of human immunodeficiency virus-related progressive multifocal leukoencephalopathy: Defining a consensus terminology

    • Paola Cinque
    • Igor J. Koralnik
    • David B. Clifford

    OriginalPaper Pages: 88 - 92

17. Gerald L Stoner (1943–2002)

    • Eugene O. Major
    • Kamel Khalili

    Obituary Pages: 93 - 93