The role of positron emission tomography in the discovery and development of new drugs; As studied in laboratory animals Peter RoseltSteven MeikleMichael Kassiou Review Article Pages: 1 - 6
Pharmacokinetics of YM466, a new factor Xa inhibitor, in rats and dogs Yuji ManoTakashi UsuiHidetaka Kamimura OriginalPaper Pages: 7 - 13
Absorption, distribution, metabolism and excretion of the cholecystokinin-1 antagonist dexloxiglumide in the dog C. WebberC. A. StokesL. F. Chasseaud OriginalPaper Pages: 15 - 23
Effect of zobo drink (Hibiscus sabdariffa water extract) on the pharmacokinetics of acetaminophen in human volunteers Kolawole J. A.Maduenyi A. OriginalPaper Pages: 25 - 29
Stimulation of lipid peroxidation and impairment of glutathione-dependent defense system in wistar rats treated with cryptopine, a rare non-narcotic opium alkaloid Ritu AnejaAnju KatyalRamesh Chandra OriginalPaper Pages: 31 - 36
Effect of erythrocytes on the hepatic distribution kinetics of antipyrine Selma SahinMalcolm Rowland OriginalPaper Pages: 37 - 41
Multiplicative dependence of the first order rate constant and its impact on clinical pharmacokinetics and bioequivalence Pietro Fagiolino OriginalPaper Pages: 43 - 49
Phenobarbital N-glucosylation by human liver microsomes Sheela G. PaibirWilliam H. SoineRobert A. Fisher OriginalPaper Pages: 51 - 59
Assessment of the sustained release properties of a new oral formulation of trimetazidine in pigs and dogs and confirmation in healthy human volunteers P. GénisselY. ChodjaniaP. Jaillon OriginalPaper Pages: 61 - 68