1. Preliminary bioequivalence testing of two nicardipine HCl sustained-release formulations with in vitro/in vivo correlations

   • Waranush Sorasuchart
   • James W. Ayres

   OriginalPaper Pages: 1 - 7

2. Induction and inactivation of a cytochrome P450 confering herbicide resistance in wheat seedlings

   • N. Forthoffer
   • C. Helvig
   • J. -P. Salaün

   OriginalPaper Pages: 9 - 16

3. The effects of a synthetic diet on the pharmacokinetics of ethyl methyl sulphide and its sulphoxide and sulphone metabolites in rats

   • I. P. Nnane
   • L. A. Damani
   • A. J. Hutt

   OriginalPaper Pages: 17 - 24

4. Comparative bioavailability of alpha-methyldopa normal and film tablet formulations after single oral administration in healthy volunteers

   • K. Róna
   • K. Ary
   • I. Klebovich

   OriginalPaper Pages: 25 - 30

5. Interactions of melatonin with the liver microsomal cytochrome P450 system of rats and humans in vitro and effects on the P450 system and the antioxidative status in rat liver after acute treatment

   • W. Klinger
   • E. Karge
   • M. Kretzschmar

   OriginalPaper Pages: 31 - 35

6. Comparison of the stability of some major cytochrome P450 and conjugation reactions in rat, dog and human hepatocyte monolayers

   • Genevieve Ubeaud
   • Claus-Ditter Schiller
   • Philippe Coassolo

   OriginalPaper Pages: 37 - 45

7. Comparative study of effects of angiotensin II receptor antagonist, KD3-671, and angiotensin converting enzyme inhibitor, enalaprilat, on cough reflex in guinea pig

   • Hidetoshi Miyamoto
   • Kiyomi Ito
   • Yasufumi Sawada

   OriginalPaper Pages: 47 - 52

8. Influence of hepatic regeneration after partial hepatectomy on theophylline pharmacokinetics in rats

   • A. M. Maza
   • A. R. Gascon
   • J. L. Pedraz

   OriginalPaper Pages: 53 - 58

9. Sensitivity analysis of pharmacodynamic parameters in pharmacodynamic models

   • Guang Wu

   OriginalPaper Pages: 59 - 63

10. Disposition of amiodarone in rats after single and multiple intraperitoneal doses

    • Tawfeeg A. O. Najjar

    OriginalPaper Pages: 65 - 69

11. Autoradiography in brain ofMacaca fascicularis monkeys after injection of acetyl-DL-leucine [2-¹⁴C] (Tanganil®)

    • P. Benard
    • H. Cousse
    • C. Germain

    OriginalPaper Pages: 71 - 76

12. Dose dependent pharmacokinetics of theophylline: Michaelis-menten parameters for its major metabolic pathways

    • Simin Dadashzadeh
    • Hosnieh Tajerzaden

    OriginalPaper Pages: 77 - 83

13. Chemical enhancers for transdermal drug transport

    • K. Bauerová
    • D. Matušová
    • Z. Kassai

    OriginalPaper Pages: 85 - 94

14. Investigation of racial variations in the metabolism of tramadol

    • D. S. Ogunleye

    OriginalPaper Pages: 95 - 98

15. Establishing individual metabolite patterns for patients on valproate therapy

    • U. Kreher
    • J. Darius
    • F. Wien

    OriginalPaper Pages: 99 - 107

16. Drug-drug interaction studies with mirtazapine and carbamazepine in healthy male subjects

    • J M A Sitsen
    • F A Maris
    • C J Timmer

    OriginalPaper Pages: 109 - 121

17. Brain microdialysis and PK/PD correlation of pregabalin in rats

    • Meihua Rose Feng
    • Daniel Turluck
    • Tizi Su

    OriginalPaper Pages: 123 - 128

18. Studies on interactions between traditional herbal and western medicines. IV: Lack of pharmacokinetic interactions between Saiko-ka-ryukotsu-borei-to and carbamazepine in rats

    • Noriaki Ohnishi
    • Shiniji Nakasako
    • Teruyoshi Yokoyama

    OriginalPaper Pages: 129 - 135

19. Determination of pharmacokinetic parameters of stavudine in Japanese patients infected with HIV-1, using a Gaussian-like input rate function

    • Shinobu Tatsunami
    • Akira Ito
    • Kaneo Yamada

    OriginalPaper Pages: 137 - 140

20. Events

    Announcement Pages: 141 - 142