1. Editorial

   • Peter J. Kielgast

   EditorialNotes Pages: 193 - 195

2. Consequence of equal absorption, distribution and/or elimination rate constants

   • Y. Plusquellec
   • F. Courbon
   • S. Nogarede

   OriginalPaper Pages: 197 - 203

3. Prediction of distribution coefficients from structure. Comparison of calculated and experimental data for various drugs

   • A. Tsantili-Kakoulidou
   • I. Panderi
   • F. Darvas

   OriginalPaper Pages: 205 - 212

4. Arteether toxicokinetics and pharmacokinetics in rats after 25 mg/kg/day single and multiple doses

   • Q-G. Li
   • R. P. Brueckner
   • T. G. Brewer

   OriginalPaper Pages: 213 - 223

5. Bioequivalence studies: biometrical concepts of alternative designs and pooled analysis

   • E. Zintzaras
   • P. Bouka

   OriginalPaper Pages: 225 - 232

6. Urinary excretion of phenobarbital and its metabolitep-hydroxyphenobarbital in convulsing and non-convulsing patients

   • B. Brzakovic
   • M. Pokrajac
   • V. M. Varagic

   OriginalPaper Pages: 233 - 236

7. Overview of stobadine bioanalysis: evaluation and application in pharmacokinetics

   • K. Bauerová

   OriginalPaper Pages: 237 - 242

8. Inhibiting effect of ethinylestradiol/levonorgestrel combination on microsomal enzymatic activities in rat liver and kidney

   • P. Czekaj
   • G. Nowaczyk-Dura

   OriginalPaper Pages: 243 - 248

9. Characterization of the highly variable bioavailability of tiludronate in normal volunteers using population pharmacokinetic methodologies

   • G. A. Maier
   • G. F. Lockwood
   • T. Grasela

   OriginalPaper Pages: 249 - 254

10. Blood and cerebrospinal fluid pharmacokinetics of primidone and its primary pharmacologically active metabolites, phenobarbital and phenylethylmalonamide in the rat

    • S. Nagaki
    • N. Ratnaraj
    • P. N. Patsalos

    OriginalPaper Pages: 255 - 264

11. Pulsed estrogen therapy: pharmacokinetics of intranasal 17-beta-estradiol (S21400) in postmenopausal women and comparison with oral and transdermal formulations

    • J-Ph. Devissaguet
    • N. Brion
    • P. Deloffre

    OriginalPaper Pages: 265 - 271

12. A further interaction study of quinine with clinically important drugs by human liver microsomes: determinations of inhibition constant (K_i) and type of inhibition

    • X-J. Zhao
    • T. Ishizaki

    OriginalPaper Pages: 272 - 278

13. Biotransformation of BOF-4272, a sulfoxide-containing drug, in the cynomolgus monkey

    • S. Naito
    • M. Nishimura
    • Y. Jin

    OriginalPaper Pages: 279 - 286

14. Events

    Announcement Pages: 287 - 288