1. Editorial

   EditorialNotes Pages: 1 - 1

2. The Drug Metabolism Discussion Group

   • D. E. Case

   BriefCommunication Pages: 2 - 2

3. Disposition kinetics of barbital in hamsters with hereditary heart failure

   • Monique Beaudoin-Jacob
   • Claude Marchand

   Original Papers Pages: 3 - 12

4. Sex differences in the biliary excretion of hypoglycaemic sulphonylureas by rats compared with non-rodents

   • T. Taylor
   • C. Gotfredsen
   • E. Doyle

   Original Papers Pages: 13 - 16

5. Comparative evaluation of the hypotensive activity of two major metabolites of hydralazine (1-hydrazinophthalazine)

   • A. J. Mclean
   • K. D. Haegele
   • J. L. Mcnay

   Original Papers Pages: 17 - 20

6. Pharmacokinetics of mianserin.HCl (Org GB 94) in the isolated perfused rat liver and in the anaesthetized rat

   • H. De Nijs
   • C. J. Timmer

   Original Papers Pages: 21 - 27

7. Disposition of procainamide and its N-acetylated metabolite after acute I.V. Infusion in man determined by high-speed liquid chromatography

   • C. Graffner
   • R. -M. Jansson
   • B. -A. Persson

   Original Papers Pages: 29 - 36

8. The physiological disposition of (6,7-dichloro-2-methyl-1-oxo-2-phenyl-5-indanyloxy) acetic acid (MK-196) in man and mouse

   • A. G. Zacchei
   • T. I. Wishousky
   • G. Hitzenberger

   Original Papers Pages: 37 - 46

9. Conference on autoradiography in pharmacology and toxicology May 22–25th, 1977, Uppsala, Sweden

   • A. B.

   Conference Report Pages: 47 - 47

10. Events

    Announcement Pages: 48 - 48