1. Placental transfer and distribution of pinazepam and its metabolite N-desmethyldiazepam in the maternal and fetal rabbit: effect of the stage of gestation

   • G. M. Pacifici
   • L. Cuoci
   • G. F. Placidi

   Original Papers Pages: 1 - 6

2. Tissue distribution and excretion of radioactively labelled compounds in the Wistar rat after administration of [N-methyl-¹⁴C]-erythromycin A

   • I.O Kibwage
   • M. Michiels
   • H. Vanderhaeghe

   Original Papers Pages: 7 - 14

3. Mefloquine disposition in normals and in patients with severePlasmodium falciparum malaria

   • F. D. Juma
   • J. O. Ogeto

   Original Papers Pages: 15 - 17

4. Study of the disposition kinetics of the N-oxide-derivative: a metabolite of picobenzide

   • D. Santos Buelga
   • E. L. MariÑo
   • A. Domínguez-Gil

   Original Papers Pages: 19 - 22

5. Plasma tenoxicam concentrations after single and multiple oral doses

   • Ch. Crevoisier
   • P. Heizmann
   • U. C. Dubach

   Original Papers Pages: 23 - 27

6. Metabolism of isobutylnaphthyl acetic acid in rats: determination of the chemical structures of metabolites

   • G. Achtert
   • F. Borchers
   • M. O. Christen

   Original Papers Pages: 29 - 34

7. The metabolism and kinetics of¹²⁵I-labeled human intravenous IgG preparation (C-425) in rats and rabbits I. Blood clearance, excretion into urine and feces, and brain uptake

   • Yasuhiro Kobayashi
   • Norihiko Kobayashi
   • Akiyo Shigematsu

   Original Papers Pages: 35 - 42

8. The metabolism and kinetics of¹²⁵I-labeled intravenous human IgG preparation (C-425) in rats and rabbits II. Excretion into bile, tissue distribution and placental permeability

   • Yasuhiro Kobayashi
   • Norihiko Kobayashi
   • Akiyo Shigematsu

   Original Papers Pages: 43 - 56

9. Effects of salbutamol on the absorption and disposition of sulphamethoxazole in adult volunteers

   • G. I. Adebayo
   • T. O. Ogundipe

   Original Papers Pages: 57 - 60

10. Metabolism of [U-¹⁴C]-4-hydroxybutyric acid to intermediates of the tricarboxylic acid cycle in extracts of rat liver and kidney mitochondria

    • K. M. Gibson
    • W. L. Nyhan

    Original Papers Pages: 61 - 70

11. Chloroquine disposition in hypersensitive and non-hypersensitive subjects and its significance in chloroquine-induced pruritus

    • E. E. Essien
    • E. I. Ette
    • E. A. Brown-Awala

    Original Papers Pages: 71 - 77

12. Pharmacokinetic interaction in beagle dogs of antiplatelet drugs: acetylsalicylic acid, dipyridamole and calcium dobesilate

    • Ch. T. Plessas
    • S. Souras
    • J. Gogas

    Original Papers Pages: 79 - 83

13. Events

    Announcement Pages: 85 - 88