Volume 8, supplement issue 1, September 2013
Molecular Neurodegeneration: Basic biology and disease pathways
92 articles in this issue
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Functional genetics – an approach to mechanisms in Alzheimer’s disease
Authors
- Mikko Hiltunen
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O3
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Role of APP in neuronal function
Authors
- Hui Zheng
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O4
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The biological function of β-secretase
Authors
- Christian Haass
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O5
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Proteomics in neurons and animals: substrates and therapeutic potential of alpha-and beta-secretase
Authors
- Stefan Lichtenthaler
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O6
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BACE1, the Alzheimer’s beta-secretase enzyme, in health and disease
Authors
- Robert Vassar
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O7
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Regulation of dynamic BACE1 trafficking in neurons
Authors (first, second and last of 18)
- Virginie Buggia-Prévot
- Celia G Fernandez
- Gopal Thinakaran
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O8
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Endogenous and exogenous regulation of gamma-secretase
Authors
- Yueming Li
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O10
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Function and dysfunction of presenilin in Alzheimer’s disease
Authors
- Jie Shen
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O11
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Genetic analysis of neurodegeneration.. the end game
Authors
- John Hardy
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O12
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Regulation of mitochondrial function by PINK1, Parkin and DJ-1
Authors
- Emilie Giaime
- Jie Shen
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O13
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Expanded G4C2 repeats linked to C9ORF72ALS and FTD form length-dependent RNA foci, sequester RNA binding proteins and are neurotoxic
Authors (first, second and last of 17)
- Youn-Bok Lee
- Han-Jou Chen
- Christopher E Shaw
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O14
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In situstudies of protein aggregation kinetics with multiparametric and superresolution imaging
Authors (first, second and last of 5)
- Gabriele Kaminski Schierle
- Claire Michel
- Clemens Kaminski
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O15
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Designing nanoparticles for delivery of neurotrophic proteins
Authors
- Angelina Angelova
- Borislav Angelov
- Sylviane Lesieur
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O16
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Novel non-carbohydrate O-GlcNAcase inhibitors with CNS drug properties as potential treatment for Alzheimer’s disease and tauopathies
Authors (first, second and last of 18)
- Heike Hering
- Danielle Graham
- Dirk Beher
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O17
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Super-resolution fluorescence imaging of intracellular mutant huntingtin protein reveals a population of fibrillar aggregates co-existing with compact perinuclear inclusion bodies
Authors (first, second and last of 5)
- Steffen J Sahl
- Lucien E Weiss
- WE Moerner
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O18
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Vascular hypothesis of Alzheimer’s disease: role of apoE and apoE receptors
Authors
- Guojun Bu
- Chia-Chen Liu
- Takahisa Kanekiyo
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O20
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Prion-like aspects of cerebral amyloidosis
Authors
- Mathias Jucker
- Lan Ye
- Sarah Fritschi
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O21
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Secretases: potential and roadblocks on the way to therapy
Authors
- Bart De Strooper
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O22
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A novel mechanism underlying pathogenesis of Down syndrome
Authors (first, second and last of 11)
- Xin Wang
- Yingjun Zhao
- Huaxi Xu
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O23
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The transcription factor XBP-1 in neurodegenerative diseases
Authors
- Frédéric Checler
- Eric Duplan
- Cristine Alves da Costa
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O24
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Transmission of alpha-synuclein in Parkinson’s disease
Authors
- Virginia M-Y Lee
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O25
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Mechanisms of Aβ induced synaptic toxicity
Authors
- Edward H Koo
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O26
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Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of AD
Authors (first, second and last of 8)
- Stephanie Fowler
- Angie Chiang
- Joanna Jankowsky
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O30
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Excitotoxicity increases the release of 24S-hydroxycholesterol via CYP46A1 activation
Authors (first, second and last of 12)
- Alejandro Sodero
- Joris Vriens
- Carlos Dotti
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O32
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Identifying dominant modifiers of mutant FUS toxicity in vivo
Authors (first, second and last of 8)
- J Gavin Daigle
- Nicholas A Lanson
- Udai Pandey
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O33
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Harnessing endogenous pathways and metabolites to treat or prevent neurodegenerative disease
Authors (first, second and last of 12)
- Todd E Golde
- Kevin Felsenstein
- Awilda Rosario
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O36
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Tau-focused therapy and tau transmission: Implications for Alzheimer’s Disease and related tauopathies
Authors
- John Q Trojanowski
- Content type: Oral presentation
- Open Access
- Published: 13 September 2013
- Article: O37
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Methylene blue decreases brain mitochondrial ABAD and amyloid beta levels protecting mitochondrial functions in LPS-mouse model
Authors
- Reham M Abdel-Kader
- Aya Zakaria
- Nabila Hamdi
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P1
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The composition of the γ-secretase complex defines its Aβ product profile
Authors (first, second and last of 4)
- Hermien Acx
- LucÃa Chávez Gutiérrez
- Bart De Strooper
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P2
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dld-1 suppression attenuates the detrimental effects of amyloid beta deposition in a Caenorhabditis elegansmodel of Alzheimer’s disease
Authors
- Waqar Ahmad
- Paul Ebert
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P3
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A new transgenic mouse model for studying the neurotoxicity of spermine oxidase dosage in the response to excitotoxic injury
Authors (first, second and last of 7)
- Emanuela Angelucci
- Sandra Moreno
- Manuela Cervelli
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P4
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RAGE targeted strategies for Alzheimer’s amyloid β peptide induced blood brain barrier dysfunctions
Authors
- Sholpan Askarova
- Andrey Tsoy
- James C-M Lee
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P5
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Development of a paradigm to investigate mechanisms of divided and selective attention impairment in the rodent models of Alzheimer’s disease
Authors
- Gytis Baranauskas
- Natasa Svirskiene
- Gytis Svirskis
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P6
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Neurochemical changes in animal models of Parkinson’s disease
Authors
- Mária Baranyi
- Elisaveta Milusheva
- Beáta Sperlágh
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P7
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CYP2E1 and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model
Authors
- Rahman Basaran
- Elcin Deniz Ozdamar
- Benay Can-Eke
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P9
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The pro-neurotrophin receptor sortilin is a major neuronal APOE receptor for catabolism of amyloid-β peptide in the brain
Authors (first, second and last of 7)
- Anne-Sophie Carlo
- Camilla Gustafsen
- Thomas Willnow
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P10
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Posterior cortical atrophy: correlation between clinical, neuropsychological, magnetic resonance and positron emission tomography Imaging
Authors
- Tinatin Chabrashvili
- Haley Lamonica
- Bassel Sawaya
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P11
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Using Caenorhabditis elegans to fight human neurodegenerative diseases
Authors (first, second and last of 5)
- Xi Chen
- Brian Kraemer
- Alan Morgan
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P12
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The dishomeostasis of metal ions plays an important role for the cognitive impartment
Authors (first, second and last of 8)
- Dehua Chui
- Huan Yang
- WeiZhong Xiao
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P13
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Platelet BACE1 levels as a possible biomarker for Alzheimer’s disease
Authors (first, second and last of 9)
- Boris Decourt
- Aaron Walker
- Marwan Sabbagh
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P14
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Altered expression of antioxidant enzymes and autophagic proteins in transglutaminase 2 knockout mice
Authors (first, second and last of 9)
- Barbara D’Orio
- Luana Barone
- Sandra Moreno
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P15
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Corynoxine isomers decrease levels of amyloid-β peptide and amyloid-β precursor protein by promoting autophagy and lysosome biogenesis
Authors (first, second and last of 6)
- Siva Sundara Kumar Durairajan
- Yingyu Huang
- Min Li
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P16
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A cell-based model of pathological tau uptake and propagation
Authors
- Ben Falcon
- Rachel Angers
- Michel Goedert
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P17
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Serum from Parkinson’s disease patients presents excess of protein halogenation and nitrosylation, with anomalous nitrosylation of serum α-synuclein as potentially etiological factor
Authors (first, second and last of 4)
- Emilio Fernandez
- Jose-Manuel Garcia-Moreno
- Jose Chacon
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P18
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The role of SorLA in neurotrophic activity and complex behavior
Authors
- Simon Glerup
- Mart Saarma
- Anders Nykjaer
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P19
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Regulation of key proteins in Alzheimer’s disease molecular pathogenesis by ubiquilin-1
Authors (first, second and last of 9)
- Mari Takalo
- Jayashree Viswanathan
- Annakaisa Haapasalo
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P20
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O-GlcNAcylation increases non-amyloidogenic processing of the amyloid-β precursor protein (APP)
Authors
- Kristin Jacobsen
- Kerstin Iverfeldt
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P21
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FcgRIIb mediates amyloid-β neurotoxicity and memory impairment in a model of Alzheimer’s disease
Authors
- Yong-Keun Jung
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P22
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Analysis of TDP-43 and its binding partners in neurodegenerative diseases
Authors (first, second and last of 5)
- Wejdan Kattuah
- Claire Troakes
- Christopher Shaw
- Content type: Poster presentation
- Open Access
- Published: 13 September 2013
- Article: P23