1. For the Special Issue on Statistical Methods for Clinical Trials and Precision Medicine

   News 27 August 2018 Pages: 281 - 282

2. Key Aspects of Modern, Quantitative Drug Development

   • Eric Gibson
   • Frank Bretz
   • Bjoern Bornkamp

   OriginalPaper 10 May 2018 Pages: 283 - 296

   

3. A New Overall-Subgroup Simultaneous Test for Optimal Inference in Biomarker-Targeted Confirmatory Trials

   • Ilana Belitskaya-Lévy
   • Hui Wang
   • Ying Lu

   OriginalPaper 04 November 2016 Pages: 297 - 323

   

4. Adaptive Biomarker Population Selection in Phase III Confirmatory Trials with Time-to-Event Endpoints

   • Xiaoyun Li
   • Cong Chen
   • Wen Li

   OriginalPaper 27 October 2016 Pages: 324 - 341

   

5. Auto-adaptive Alpha Allocation: A Strategy to Mitigate Risk on Study Assumptions

   • Yue Shentu
   • Cong Chen
   • Robert A. Beckman

   OriginalPaper 10 May 2017 Pages: 342 - 356

   

6. Population-Enrichment Adaptive Design Strategy for an Event-Driven Vaccine Efficacy Trial

   • Shu-Chih Su
   • Xiaoming Li
   • Ivan S. F. Chan

   OriginalPaper 11 September 2017 Pages: 357 - 370

   

7. Biomarker-Defined Subgroup Selection Adaptive Design for Phase III Confirmatory Trial with Time-to-Event Data: Comparing Group Sequential and Various Adaptive Enrichment Designs

   • Rui Tang
   • Xiaoye Ma
   • Michael Wolf

   OriginalPaper 12 June 2017 Pages: 371 - 404

   

8. Efficiency Considerations for Group Sequential Designs with Adaptive Unblinded Sample Size Re-assessment

   • Lingyun Liu
   • Sam Hsiao
   • Cyrus R. Mehta

   OriginalPaper 15 March 2017 Pages: 405 - 419

   

9. Bayesian Adaptive Randomization and Trial Monitoring with Predictive Probability for Time-to-Event Endpoint

   • Guosheng Yin
   • Nan Chen
   • J. Jack Lee

   OriginalPaper 17 June 2017 Pages: 420 - 438

   

10. Bayesian Design of Non-inferiority Clinical Trials Via the Bayes Factor

    • Wenqing Li
    • Ming-Hui Chen
    • Dipak K. Dey

    OriginalPaper 06 July 2017 Pages: 439 - 459

    

11. Some Recent Advances on Statistical Approaches for Planning Multi-regional Clinical Trials

    • H. M. James Hung
    • Xiangmin Zhang
    • Sue-Jane Wang

    OriginalPaper 12 June 2017 Pages: 460 - 472

    

12. Estimating Treatment Effects for Recurrent Events in the Presence of Rescue Medications: An Application to the Immune Thrombocytopenia Study

    • Fei Gao
    • Donglin Zeng
    • Joseph G. Ibrahim

    OriginalPaper 29 August 2016 Pages: 473 - 489