Structure and Inhibitor Specificity of L,D-Transpeptidase (LdtMt2) from Mycobacterium tuberculosis and Antibiotic Resistance: Calcium Binding Promotes Dimer Formation Kuppan GokulanSangeeta KhareKottayil I. Varughese Research Article 09 March 2018 Article: 44
Receptor Occupancy Imaging Studies in Oncology Drug Development Ingrid J. G. BurvenichSagun ParakhAndrew M. Scott Review Article 08 March 2018 Article: 43
Structural Elucidation of Metabolites of Synthetic Cannabinoid UR-144 by Cunninghamella elegans Using Nuclear Magnetic Resonance (NMR) Spectroscopy Shimpei WatanabeUnnikrishnan KuzhiumparambilShanlin Fu Research Article 08 March 2018 Article: 42
Recent Advances in Exosomal Protein Detection Via Liquid Biopsy Biosensors for Cancer Screening, Diagnosis, and Prognosis Chang LiuYunchen YangYun Wu Review Article 08 March 2018 Article: 41
Application of Pharmacometric Analysis in the Design of Clinical Pharmacology Studies for Biosimilar Development Peijuan ZhuSherwin K. B. SyAndrej Skerjanec Tutorial 07 March 2018 Article: 40
Model-Based Adaptive Optimal Design (MBAOD) Improves Combination Dose Finding Designs: an Example in Oncology Philippe B. PierrillasSylvain FouliardMats O. Karlsson Research Article Open access 07 March 2018 Article: 39
Correction to: Recommendations for the Development and Validation of Neutralizing Antibody Assays in Support of Biosimilar Assessment D. GoutyC. C. CaiC. Satterwhite Correction 27 February 2018 Article: 38
Targeting Inflammatory Vasculature by Extracellular Vesicles Sihan WangXinyue DongZhenjia Wang Mini-Review 26 February 2018 Article: 37
New Perspectives in Clinical Pharmacokinetics-1: the Importance of Updating the Teaching in Pharmacokinetics that both Clearance and Elimination Rate Constant Approaches Are Mathematically Proven Equally Valid Roger JelliffeDavid Bayard Tutorial 26 February 2018 Article: 36
Reporting, Visualization, and Modeling of Immunogenicity Data to Assess Its Impact on Pharmacokinetics, Efficacy, and Safety of Monoclonal Antibodies Chaitali PasseySatyendra SuryawanshiManish Gupta Review Article 26 February 2018 Article: 35
Targeted Delivery of Doxorubicin via CD147-Mediated ROS/pH Dual-Sensitive Nanomicelles for the Efficient Therapy of Hepatocellular Carcinoma Chenxi QuJizhao LiXuenong Zhang Research Article 23 February 2018 Article: 34
Effect of Cryopreservation on Enzyme and Transporter Activities in Suspended and Sandwich Cultured Rat Hepatocytes Janneke KeeminkNeel DefermPieter Annaert Research Article 21 February 2018 Article: 33
Fucoxanthin Elicits Epigenetic Modifications, Nrf2 Activation and Blocking Transformation in Mouse Skin JB6 P+ Cells Yuqing YangIrene YangAh-Ng Kong Research Article 20 February 2018 Article: 32
Pediatric Dose Selection and Utility of PBPK in Determining Dose Ian E. TempletonNicholas S. JonesLuna Musib Research Article 13 February 2018 Article: 31
Correction to: Pluripotent Stem Cell-Derived Human Tissue: Platforms to Evaluate Drug Metabolism and Safety Jose Meseguer-RipollesSalman R. KhetaniDavid C. Hay Correction 12 February 2018 Article: 30
New Scaffold for Lead Compounds to Treat Methamphetamine Use Disorders Na-Ra LeeGuangrong ZhengLinda P. Dwoskin Research Article 09 February 2018 Article: 29
Cancer Immunotherapy: Factors Important for the Evaluation of Safety in Nonclinical Studies Danuta J. HerzykHelen G. Haggerty Review Article 07 February 2018 Article: 28
Correction to: In Vitro-In Vivo Dose Response of Ursolic Acid, Sulforaphane, PEITC, and Curcumin in Cancer Prevention Christina N. RamirezWenji LiAh-Ng Tony Kong Correction 06 February 2018 Article: 27
Common Deficiencies of in vitro Binding Bioequivalence (BE) Studies Submitted in Abbreviated New Drug Applications (ANDAs) Dongmei LuDiana VivianEthan Stier Regulatory Note 11 January 2018 Article: 26
