Recommendations for Validation of LC-MS/MS Bioanalytical Methods for Protein Biotherapeutics Rand JenkinsJeffrey X. DugganFaye Vazvaei White Paper 13 November 2014 Pages: 1 - 16
Tiered Approaches to Chromatographic Bioanalytical Method Performance Evaluation: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team S. LowesR. HuckerD. Zimmer Commentary 23 October 2014 Pages: 17 - 23
Impact of Data Base Structure in a Successful In Vitro-In Vivo Correlation for Pharmaceutical Products B. RoudierB. DavitJ-M. Cardot Commentary 12 November 2014 Pages: 24 - 34
Immunogenicity of Antibody Drug Conjugates: Bioanalytical Methods and Monitoring Strategy for a Novel Therapeutic Modality M. Benjamin HockKaren E. ThudiumNikolai F. Schwabe Meeting Report 08 November 2014 Pages: 35 - 43
Summary Report of PQRI Workshop on Nanomaterial in Drug Products: Current Experience and Management of Potential Risks Jeremy A. BartlettMarcus BrewsterWilliam Zamboni Meeting Report 25 November 2014 Pages: 44 - 64
Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update Qingcheng MaoJashvant D. Unadkat Review Article 19 September 2014 Pages: 65 - 82
Lipid-Based Drug Carriers for Prodrugs to Enhance Drug Delivery Jennica L. Zaro Review Article 01 October 2014 Pages: 83 - 92
Emerging Technologies to Increase Ligand Binding Assay Sensitivity Saloumeh K. FischerAlison JoyceAlvydas Mikulskis Review Article 18 October 2014 Pages: 93 - 101
Gene-Directed Enzyme Prodrug Therapy Jin ZhangVijay KaleMingnan Chen Review Article 23 October 2014 Pages: 102 - 110
Early Engineering Approaches to Improve Peptide Developability and Manufacturability Jennifer L. FurmanMark ChiuMichael J. Hunter Review Article 23 October 2014 Pages: 111 - 120
Survey of International Regulatory Bioequivalence Recommendations for Approval of Generic Topical Dermatological Drug Products April C. BraddyBarbara M. DavitDale P. Conner Review Article 25 October 2014 Pages: 121 - 133
Strategic Approaches to Optimizing Peptide ADME Properties Li Di Review Article 04 November 2014 Pages: 134 - 143
Physicochemical and Formulation Developability Assessment for Therapeutic Peptide Delivery—A Primer Annette BakDennis LeungLouis S. Crocker Review Article 15 November 2014 Pages: 144 - 155
Regioselective Glucuronidation of Andrographolide and Its Major Derivatives: Metabolite Identification, Isozyme Contribution, and Species Differences Xiangge TianSicheng LiangXiaochi Ma Research Article 10 September 2014 Pages: 156 - 166
Design and Characterisation of a Polyethylene Oxide Matrix with the Potential Use as a Teat Insert for Prevention/Treatment of Bovine Mastitis Sushila BhattaraiRaid G. AlanyMichael J. Rathbone Research Article 16 October 2014 Pages: 167 - 174
Comparative Pharmacology and Toxicology of Pharmaceuticals in the Environment: Diphenhydramine Protection of Diazinon Toxicity in Danio rerio but Not Daphnia magna Lauren A. KristofcoBowen DuBryan W. Brooks Research Article 18 October 2014 Pages: 175 - 183
Biodegradable Microparticles Loaded with Doxorubicin and CpG ODN for In Situ Immunization Against Cancer Amani MakkoukVijaya B. JoshiGeorge J. Weiner Research Article 18 October 2014 Pages: 184 - 193
Continuous Production of Fenofibrate Solid Lipid Nanoparticles by Hot-Melt Extrusion Technology: a Systematic Study Based on a Quality by Design Approach Hemlata PatilXin FengMichael A. Repka Research Article 25 October 2014 Pages: 194 - 205
Analysis of Imprecision in Incurred Sample Reanalysis for Small Molecules Sriram SubramaniamDevvrat PatelDale P. Conner Research Article 30 October 2014 Pages: 206 - 215
Cationic Liposomes Loaded with a Synthetic Long Peptide and Poly(I:C): a Defined Adjuvanted Vaccine for Induction of Antigen-Specific T Cell Cytotoxicity Eleni Maria VarypatakiKoen van der MaadenWim Jiskoot Research Article 12 November 2014 Pages: 216 - 226
Empirical and Semi-Mechanistic Modelling of Double-Peaked Pharmacokinetic Profile Phenomenon Due to Gastric Emptying Kayode OgungbenroHenry PertinezLeon Aarons Research Article 21 November 2014 Pages: 227 - 236
Impact of Glycation on Antibody Clearance Jane YangRonya PrimackGregory C. Flynn Research Article 21 November 2014 Pages: 237 - 244
Performance of Nonlinear Mixed Effects Models in the Presence of Informative Dropout Marcus A. BjörnssonLena E. FribergUlrika S. H. Simonsson Research Article 25 November 2014 Pages: 245 - 255
Safety and Biocompatibility of Carbohydrate-Functionalized Polyanhydride Nanoparticles Julia E. Vela-RamirezJonathan T. GoodmanBalaji Narasimhan Research Article 25 November 2014 Pages: 256 - 267
Pharmacodynamics of Telomerase Inhibition and Telomere Shortening by Noncytotoxic Suramin Yuebo GanJie LuJessie L.-S. Au Research Article 26 November 2014 Pages: 268 - 276