1. Preface

   • Grace Y. Sun
   • W. Gibson Wood

   EditorialNotes 13 April 2010 Pages: 53 - 54

   

2. Redox Reactions Induced by Nitrosative Stress Mediate Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative Diseases

   • Zezong Gu
   • Tomohiro Nakamura
   • Stuart A. Lipton

   ReviewPaper 25 March 2010 Pages: 55 - 72

   

3. Targeting NADPH Oxidase and Phospholipases A₂ in Alzheimer’s Disease

   • Agnes Simonyi
   • Yan He
   • Grace Y. Sun

   ReviewPaper 02 March 2010 Pages: 73 - 86

   

4. Abnormal Mitochondrial Dynamics—A Novel Therapeutic Target for Alzheimer's Disease?

   • Bo Su
   • Xinglong Wang
   • Xiongwei Zhu

   ReviewPaper 27 January 2010 Pages: 87 - 96

5. The Pathogenic Implication of Abnormal Interaction Between Apolipoprotein E Isoforms, Amyloid-beta Peptides, and Sulfatides in Alzheimer’s Disease

   • Xianlin Han

   ReviewPaper 07 January 2010 Pages: 97 - 106

   

6. Convergence of Amyloid-β and Tau Pathologies on Mitochondria In Vivo

   • Anne Eckert
   • Kathrin L. Schulz
   • Jürgen Götz

   ReviewPaper Open access 09 March 2010 Pages: 107 - 114

   

7. Microglia Activation and Anti-inflammatory Regulation in Alzheimer’s Disease

   • Lih-Fen Lue
   • Yu-Min Kuo
   • Douglas G. Walker

   ReviewPaper 03 March 2010 Pages: 115 - 128

   

8. Cyclic GMP and Nitric Oxide Synthase in Aging and Alzheimer's Disease

   • Katarzyna Urszula Domek-Łopacińska
   • Joanna B. Strosznajder

   ReviewPaper 09 March 2010 Pages: 129 - 137

   

9. Membrane Biophysics and Mechanics in Alzheimer's Disease

   • Xiaoguang Yang
   • Sholpan Askarova
   • James C-M. Lee

   ReviewPaper 01 May 2010 Pages: 138 - 148

10. Arginine Metabolising Enzymes as Therapeutic Tools for Alzheimer’s Disease: Peptidyl Arginine Deiminase Catalyses Fibrillogenesis of β-amyloid Peptides

    • Peter Mohlake
    • Chris G. Whiteley

    ReviewPaper 12 March 2010 Pages: 149 - 158

    

11. Mitochondrial Dysfunction: Common Final Pathway in Brain Aging and Alzheimer’s Disease—Therapeutic Aspects

    • Walter E. Müller
    • Anne Eckert
    • Kristina Leuner

    ReviewPaper 12 May 2010 Pages: 159 - 171

    

12. Reperfusion and Neurovascular Dysfunction in Stroke: from Basic Mechanisms to Potential Strategies for Neuroprotection

    • Joo Eun Jung
    • Gab Seok Kim
    • Pak H. Chan

    ReviewPaper 17 February 2010 Pages: 172 - 179

    

13. Anti-apoptotic Actions of PPAR-γ Against Ischemic Stroke

    • Wen-Hsuan Fong
    • Hsin-Da Tsai
    • Teng-Nan Lin

    ReviewPaper 03 February 2010 Pages: 180 - 186

    

14. Poly(ADP-Ribose) Metabolism in Brain and Its Role in Ischemia Pathology

    • Robert Piotr Strosznajder
    • Kinga Czubowicz
    • Joanna Benigna Strosznajder

    ReviewPaper 23 April 2010 Pages: 187 - 196

    

15. Phospholipase A₂ and its Molecular Mechanism after Spinal Cord Injury

    • Nai-Kui Liu
    • Xiao-Ming Xu

    ReviewPaper 03 February 2010 Pages: 197 - 205

    

16. Protection by D609 Through Cell-Cycle Regulation After Stroke

    • Rao Muralikrishna Adibhatla
    • James F. Hatcher

    ReviewPaper 12 February 2010 Pages: 206 - 217

    

17. 14-3-3γ and Neuroglobin are New Intrinsic Protective Factors for Cerebral Ischemia

    • Yan Dong
    • Rui Zhao
    • Albert Cheung Hoi Yu

    ReviewPaper 14 May 2010 Pages: 218 - 231

    

18. Astrogliosis in CNS Pathologies: Is There A Role for Microglia?

    • Dan Zhang
    • Xiaoming Hu
    • Jau-Shyong Hong

    ReviewPaper 12 February 2010 Pages: 232 - 241

    

19. Inflammatory Neurodegeneration and Mechanisms of Microglial Killing of Neurons

    • Guy C. Brown
    • Jonas J. Neher

    ReviewPaper 02 March 2010 Pages: 242 - 247

20. Targeting Glial Cells to Elucidate the Pathogenesis of Huntington’s Disease

    • Han-Yun Hsiao
    • Yijuang Chern

    ReviewPaper 28 January 2010 Pages: 248 - 255

    

21. Mitochondrial DNA Mutation-Elicited Oxidative Stress, Oxidative Damage, and Altered Gene Expression in Cultured Cells of Patients with MERRF Syndrome

    • Shi-Bei Wu
    • Yi-Shing Ma
    • Yau-Huei Wei

    ReviewPaper 23 April 2010 Pages: 256 - 266

    

22. Studies on Plasmalogen-Selective Phospholipase A₂ in Brain

    • Akhlaq A. Farooqui

    ReviewPaper 06 January 2010 Pages: 267 - 273

    

23. Low Molecular Weight Phospholipases A₂ in Mammalian Brain and Neural Cells: Roles in Functions and Dysfunctions

    • Gianfrancesco Goracci
    • Monica Ferrini
    • Vincenza Nardicchi

    ReviewPaper 19 March 2010 Pages: 274 - 289

    

24. A Hapten Generated from an Oxidation Fragment of Docosahexaenoic Acid Is Sufficient to Initiate Age-Related Macular Degeneration

    • Joe G. Hollyfield
    • Victor L. Perez
    • Robert G. Salomon

    ReviewPaper 12 March 2010 Pages: 290 - 298

    

25. Changes in Brain Cholesterol Metabolome After Excitotoxicity

    • Wei-Yi Ong
    • Ji-Hyun Kim
    • Andrew M. Jenner

    ReviewPaper 06 February 2010 Pages: 299 - 313

    

26. Deregulated Sphingolipid Metabolism and Membrane Organization in Neurodegenerative Disorders

    • Marco Piccinini
    • Federica Scandroglio
    • Alessandro Prinetti

    ReviewPaper 03 February 2010 Pages: 314 - 340

    

27. Modulation of Cholesterol, Farnesylpyrophosphate, and Geranylgeranylpyrophosphate in Neuroblastoma SH-SY5Y-APP695 Cells: Impact on Amyloid Beta-Protein Production

    • Gero P. Hooff
    • Imke Peters
    • Gunter P. Eckert

    ReviewPaper 21 April 2010 Pages: 341 - 350

    

28. Roles of P2X₇ Receptor in Glial and Neuroblastoma Cells: The Therapeutic Potential of P2X₇ Receptor Antagonists

    • Synthia H. Sun

    ReviewPaper 21 April 2010 Pages: 351 - 355

29. P2Y₂ Nucleotide Receptor-Mediated Responses in Brain Cells

    • Troy S. Peterson
    • Jean M. Camden
    • Gary A. Weisman

    ReviewPaper 13 April 2010 Pages: 356 - 366

    

30. Omega-3 Essential Fatty Acids Modulate Initiation and Progression of Neurodegenerative Disease

    • R. Palacios-Pelaez
    • Walter J. Lukiw
    • Nicolas G. Bazan

    ReviewPaper 14 May 2010 Pages: 367 - 374

    

31. Resveratrol as a Therapeutic Agent for Neurodegenerative Diseases

    • Albert Y. Sun
    • Qun Wang
    • Grace Y. Sun

    ReviewPaper 21 March 2010 Pages: 375 - 383

    

32. Simvastatin Stimulates Production of the Antiapoptotic Protein Bcl-2 via Endothelin-1 and NFATc3 in SH-SY5Y Cells

    • Tammy A. Butterick
    • Urule Igbavboa
    • W. Gibson Wood

    ReviewPaper 06 April 2010 Pages: 384 - 391

    

33. Why Pleiotropic Interventions are Needed for Alzheimer's Disease

    • Sally A. Frautschy
    • Greg M. Cole

    ReviewPaper Open access 02 May 2010 Pages: 392 - 409

    

34. Post-MPTP Treatment with Granulocyte Colony-Stimulating Factor Improves Nigrostriatal Function in the Mouse Model of Parkinson’s Disease

    • Mark McCollum
    • Zhiyuan Ma
    • Jianning Wei

    ReviewPaper 21 April 2010 Pages: 410 - 419

    

35. Moderate Ethanol Preconditioning of Rat Brain Cultures Engenders Neuroprotection Against Dementia-Inducing Neuroinflammatory Proteins: Possible Signaling Mechanisms

    • Michael A. Collins
    • Edward J. Neafsey
    • Sreevidya Sivaswamy

    ReviewPaper 28 April 2010 Pages: 420 - 425