Knockdown of HMGN5 suppresses the viability and invasion of human urothelial bladder cancer 5637 cells in vitro and in vivo Yu GanJing TanYuxin Tang Original Paper 22 March 2015 Article: 136
Satisfactory outcome after intensive chemotherapy with pragmatic use of minimal residual disease (MRD) monitoring in older patients with Philadelphia-negative B cell precursor acute lymphoblastic leukaemia: a Swedish registry-based study Emma BergfeltPiotr KozlowskiHeléne Hallböök Short Communication 22 March 2015 Article: 135
Switch maintenance treatment with oral vinorelbine and bevacizumab after induction chemotherapy with cisplatin, gemcitabine and bevacizumab in patients with advanced non-squamous non-small cell lung cancer: a phase II study Roberto PetrioliEdoardo FranciniGiandomenico Roviello Original Paper 22 March 2015 Article: 134
Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin Xingchao ZhuKaiguang ZhangQin Li Original Paper 22 March 2015 Article: 133
Mitofusin-2 over-expresses and leads to dysregulation of cell cycle and cell invasion in lung adenocarcinoma Yuqing LouRong LiBaohui Han Original Paper 22 March 2015 Article: 132
Overexpression of AGGF1 is correlated with angiogenesis and poor prognosis of hepatocellular carcinoma Wei WangGuang-Yao LiChu-Shu Ji Original Paper 22 March 2015 Article: 131
Construction, expression, and function of 6B11ScFv–mIL-12, a fusion protein that attacks human ovarian carcinoma Hongyan ChengXue YeJianli Sang Original Paper 21 March 2015 Article: 130
A phase I pilot study of the insulin-like growth factor 1 receptor pathway modulator AXL1717 in combination with gemcitabine HCl and carboplatin in previously untreated, locally advanced, or metastatic non-small cell lung cancer Georg HolgerssonStefan BergströmMichael Bergqvist Original Paper 21 March 2015 Article: 129
Suppression of the nuclear transporter-KPNβ1 expression inhibits tumor proliferation in hepatocellular carcinoma Linlin YangBaoying HuJibin Liu Letter to the Editor 21 March 2015 Article: 128
Cetuximab in patients with esophageal cancer: a systematic review and meta-analysis of randomized controlled trials Xu TianJian-Guo ZhouGuo-Min Song Review Article 21 March 2015 Article: 127
Rab40b upregulation correlates with the prognosis of gastric cancer by promoting migration, invasion, and metastasis Yuanyuan LiQingzhu JiaYing Wan Original Paper 20 March 2015 Article: 126
The effects of focal adhesion kinase on the motility, proliferation and apoptosis of Caco2 and SMMC-7721 cells Ning GaoHuimin HeYingchun Hou Original Paper 20 March 2015 Article: 125
Galectin-3 knockdown increases gefitinib sensitivity to the inhibition of EGFR endocytosis in gefitinib-insensitive esophageal squamous cancer cells Guanghui CuiMingwei CuiSong Zhao Original Paper 19 March 2015 Article: 124
The more we use, the more we lose Ali AlkanDılşa MızrakGüngör Utkan Letter to the Editor 19 March 2015 Article: 123
Methods of reconstruction after esophagectomy on long-term health-related quality of life: a prospective, randomized study of 5-year follow-up Min ZhangQiang LiQing-Chen Wu Original Paper 19 March 2015 Article: 122
Cost-effectiveness analysis of gemcitabine, S-1 and gemcitabine plus S-1 for treatment of advanced pancreatic cancer based on GEST study Jing ZhouRongce ZhaoQiu Li Original Paper 19 March 2015 Article: 121
Evaluation of Clavien–Dindo classification in patients undergoing total gastrectomy for gastric cancer Junfeng ZhouPeiwu YuFeng Qian Original Paper 19 March 2015 Article: 120
Erratum to: Single-agent bevacizumab is an effective treatment in recurrent glioblastoma Ilhan HacibekirogluHilmi KodazIrfan Cicin Erratum 19 March 2015 Article: 119
TAT-OSBP-1-MKK6(E), a novel TAT-fusion protein with high selectivity for human ovarian cancer, exhibits anti-tumor activity Jiali ZhongJiali KangJin Yuan Original Paper 18 March 2015 Article: 118
Relationship between LINE-1 hypomethylation and Helicobacter pylori infection in gastric mucosae Keisuke KosumiYoshifumi BabaHideo Baba Original Paper 18 March 2015 Article: 117
Study on the mesothelin-specific cytotoxicity against epithelial ovarian cancer with full-length mesothelin cDNA-transduced dendritic cells Dong-hui WangXiao-hua WuHai-Rong Yao Original Paper 17 March 2015 Article: 116
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway Wei HuangJie LiuCaiping Ren Original Paper 17 March 2015 Article: 115
Comprehensive geriatric assessment and traditional Chinese medicine intervention benefit symptom control in elderly patients with advanced non-small cell lung cancer Dong XueShuyan HanPingping Li Original Paper 15 March 2015 Article: 114
Neutrophil-guided dosing of anthracycline–cyclophosphamide-containing chemotherapy in patients with breast cancer: a feasibility study Jan C. DroogerJohanna M. van Pelt-SprangersFelix E. de Jongh Original Paper Open access 13 March 2015 Article: 113
Serine protease HtrA1 as an inhibitor on proliferation invasion and migration of gastric cancer Zhiguo ZhaoHuifang LiWenzhao Zhao Original Paper 12 March 2015 Article: 112
PI3K/AKT/mTOR pathway is activated after imatinib secondary resistance in gastrointestinal stromal tumors (GISTs) Jian LiYunzhi DangLin Shen Original Paper 11 March 2015 Article: 111
Outcomes of dose-adjusted Berlin–Frankfurt–Münster-90 regimen without radiotherapy in adolescents and adults with T cell lymphoblastic lymphoma Yan XieYuntao ZhangJun Zhu Original Paper Open access 10 March 2015 Article: 110
Infection and integration of high-risk human papillomavirus in HPV-associated cancer cells Chu-Yi LiuFan LiRu-Gang Zhong Original Paper 08 March 2015 Article: 109
Induction FOLFOX followed by preoperative hyperfractionated radiotherapy plus bolus 5-fluorouracil in locally advanced rectal carcinoma: single arm phase I–II study Engy M. AboelnagaMohamed A. DaoudAmir M. Zaid Original Paper 07 March 2015 Article: 108
Adjuvant sorafenib therapy in patients with resected hepatocellular carcinoma: evaluation of predictive factors Wei ZhangGang ZhaoTianqiang Song Original Paper 07 March 2015 Article: 107
Perspectives and practical applications of medical oncologists on defensive medicine (SYSIPHUS study): a study of the Palliative Care Working Committee of the Turkish Oncology Group (TOG) Ozgur TanriverdiFiliz Cay-SenlerOzgur Ozyilkan Original Paper 07 March 2015 Article: 106
Enhanced expression of suppresser of cytokine signaling 3 inhibits the IL-6-induced epithelial-to-mesenchymal transition and cholangiocarcinoma cell metastasis Qing-Xin ZhouXing-Ming JiangYun-Fu Cui Original Paper 06 March 2015 Article: 105
G protein-coupled estrogen receptor (GPER) mediates NSCLC progression induced by 17β-estradiol (E2) and selective agonist G1 Changyu LiuYongde LiaoJianmiao Wang Original Paper 06 March 2015 Article: 104
Downregulation of ABCE1 via siRNA affects the sensitivity of A549 cells against chemotherapeutic agents Göknur KaraSema TuncerEmir Baki Denkbaş Original Paper 06 March 2015 Article: 103
Down-regulation of Frizzled-7 expression inhibits migration, invasion, and epithelial–mesenchymal transition of cervical cancer cell lines Boya DengSiyang ZhangKejun Guo Original Paper 05 March 2015 Article: 102
Hesperetin induces the apoptosis of hepatocellular carcinoma cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species, ATP and calcium Jixiang ZhangJia SongWeiguo Dong Original Paper 04 March 2015 Article: 101
Combined treatment of carfilzomib and z-VAD-fmk inhibits skeletal proteolysis and apoptosis and ameliorates cancer cachexia Qiang WangChunhong LiHua Tang Original Paper 04 March 2015 Article: 100
Increased Sushi repeat-containing protein X-linked 2 is associated with progression of colorectal cancer K. L. LiuJ. WuJ. H. Fan Original Paper 04 March 2015 Article: 99
Down-expression pattern of Ku70 and p53 coexisted in colorectal cancer Yuanfang LuJingyan GaoYuanming Lu Original Paper 04 March 2015 Article: 98
Wnt2 protein plays a role in the progression of pancreatic cancer promoted by pancreatic stellate cells Yong XuHua LiJihui Hao Original Paper 03 March 2015 Article: 97
Meta-analysis of gene expression profiles indicates genes in spliceosome pathway are up-regulated in hepatocellular carcinoma (HCC) Weijin XuHuixing HuangLihuan Cao Original Paper 03 March 2015 Article: 96
Wnt signaling regulates the stemness of lung cancer stem cells and its inhibitors exert anticancer effect on lung cancer SPC-A1 cells Xueyan ZhangYuqing LouBaohui Han Original Paper 03 March 2015 Article: 95
Intensity-modulated radiotherapy and volumetric-modulated arc therapy have distinct clinical advantages in non-small cell lung cancer treatment Jun ZhangXiao-Ling YuFei Zhao Original Paper 01 March 2015 Article: 94
Systemic treatment with capecitabine as maintenance therapy in patients with recurring or metastatic breast cancer: experience in the Oncology Hospital, National Medical Center Siglo XXI, Mexican Social Security Institute Manuel Segura-GonzálezMiguel Quintana-Quintana Original Paper 27 February 2015 Article: 93
Aberrant gene promoter methylation of p16, FHIT, CRBP1, WWOX, and DLC-1 in Epstein–Barr virus-associated gastric carcinomas Dan HeYi-wang ZhangChun-kui Shao Original Paper 27 February 2015 Article: 92
PPARγ suppressed Wnt/β-catenin signaling pathway and its downstream effector SOX9 expression in gastric cancer cells Xiyun RenDongyou ZhengWenjing Tian Original Paper 27 February 2015 Article: 91
Liposomal cytarabine in the prophylaxis and treatment of CNS lymphoma: toxicity analysis in a retrospective case series study conducted at Polish Lymphoma Research Group Centers Wojciech JurczakRenata Kroll-BalcerzakMieczysław Komarnicki Original Paper Open access 26 February 2015 Article: 90
High efficacy of cisplatin neoadjuvant therapy in a prospective series of patients carrying BRCA1 germ-line mutation Vladimir M. MoiseyenkoGeorgiy D. DolmatovEvgeny N. Imyanitov Short Communication 25 February 2015 Article: 89
Utility and cost-effectiveness of screening for hepatocellular carcinoma in a resource-limited setting Z. R. XieY. L. Luo Letter to the Editor 24 February 2015 Article: 88
GATA2 promotes glioma progression through EGFR/ERK/Elk-1 pathway Zhongyong WangHui YuanQing Lan Original Paper 24 February 2015 Article: 87
