1. Cardioprotection with Sodium-Hydrogen Exchange Inhibition: An Archetype of "Bench to Bedside"

   • Karin Przyklenk

   OriginalPaper Pages: 5 - 6

2. Introduction

   • Morris Karmazyn
   • Wolfgang Scholz

   OriginalPaper Pages: 7 - 8

3. Functional and Cellular Regulation of the Myocardial Na+/H+ Exchanger

   • Larry Fliegel

   OriginalPaper Pages: 9 - 14

4. Sodium-Hydrogen Exchange and Platelet Function

   • Dieter Rosskopf

   OriginalPaper Pages: 15 - 24

5. Regulation of Cardiac Sarcolemmal Na+/H+ Exchanger Activity: Potential Pathophysiological Significance of Endogenous Mediators and Oxidant Stress

   • Metin Avkiran
   • Andrew K. Snabaitis

   OriginalPaper Pages: 25 - 32

6. Mechanisms of Protection of the Ischemic and Reperfused Myocardium by Sodium-Hydrogen Exchange Inhibition

   • Morris Karmazyn

   OriginalPaper Pages: 33 - 38

7. If Ischemic Preconditioning Is the Gold Standard, Has a Platinum Standard of Cardioprotection Arrived? Comparison with NHE Inhibition

   • Richard J. Gumina
   • Garrett J. Gross

   OriginalPaper Pages: 39 - 44

8. Role of the Sodium-Hydrogen Exchanger in Ischemia-Reperfusion Injury in Diabetes

   • Danny P. Goel
   • Grant N. Pierce

   OriginalPaper Pages: 45 - 52

9. Protection of the Myocardium with Sodium-Hydrogen Exchange Inhibitors: A Cardiac Surgical Perspective

   • Mary Lee Myers

   OriginalPaper Pages: 53 - 60

10. Development of the Na+/H+ Exchange Inhibitor Cariporide as a Cardioprotective Drug: From the Laboratory to the GUARDIAN Trial

    • Wolfgang Scholz
    • Andreas Jessel
    • Udo Albus

    OriginalPaper Pages: 61 - 70