Transdermal Delivery of Bioactive Peptides: The Effect of n-Decylmethyl Sulfoxide, pH, and Inhibitors on Enkephalin Metabolism and Transport Hoo-Kyun ChoiGordon L. FlynnGordon L. Amidon OriginalPaper Pages: 1099 - 1106
Dose and Time-Course Evaluation of a Redox-Based Estradiol-Chemical Delivery System for the Brain. II. Pharmacodynamic Responses Mohamad H. RahimyJames W. SimpkinsNicholas Bodor OriginalPaper Pages: 1107 - 1112
A Sensitive and Specific Liquid-Chromatographic Assay for Determination of Ganciclovir in Plasma and Urine and Its Application to Pharmacokinetic Studies in the Rabbit Mohsen A. HedayaRonald J. Sawchuk OriginalPaper Pages: 1113 - 1118
Characterization of a Hot-Melt Fluid Bed Coating Process for Fine Granules Michael J. JozwiakowskiDavid M. JonesRobert M. Franz OriginalPaper Pages: 1119 - 1126
Nebulization of Liposomes. I. Effects of Lipid Composition Ralph W. NivenHans Schreier OriginalPaper Pages: 1127 - 1133
Theophylline-Controlled Release Preparations and Fatty Food: An in Vitro Study Using the Rotating Dialysis Cell Method Silvia K. El-AriniGerald K. ShiuJerome P. Skelly OriginalPaper Pages: 1134 - 1140
Electrical Analysis of Fresh, Excised Human Skin: A Comparison with Frozen Skin Gerald B. KastingLisa A. Bowman OriginalPaper Pages: 1141 - 1146
In Vitro Skin Absorption and Metabolism of Benzoic Acid, p-Aminobenzoic Acid, and Benzocaine in the Hairless Guinea Pig David NathanAdel SakrRobert L. Bronaugh OriginalPaper Pages: 1147 - 1151
Enhancement of the Antiinflammatory Effect of Ethyl 4-Biphenylyl Acetate in Ointment by β-Cyclodextrin Derivatives: Increased Absorption and Localized Activation of the Prodrug in Rats Hidetoshi ArimaHirotoshi AdachiJosef Pitha OriginalPaper Pages: 1152 - 1156
Solid and Liquid Heat Capacities of n-Alkyl Para-aminobenzoates Near the Melting Point Steven H. NeauGordon L. Flynn OriginalPaper Pages: 1157 - 1162
Gastrointestinal Transit of Nondisintegrating, Nonerodible Oral Dosage Forms in Pigs Mohammad HossainWattanaporn AbramowitzJames W. Ayres OriginalPaper Pages: 1163 - 1166
Release and Absorption Characteristics of Novel Theophylline Sustained-Release Formulations: In Vitro-in Vivo Correlation Ziad HusseinMichael Friedman OriginalPaper Pages: 1167 - 1171
Evaluation of the Pharmacokinetic Interaction Between Diazepam and ACC-9653 (a Phenytoin Prodrug) in Healthy Male Volunteers Elizabeth K. HusseyGeorge E. DukesLawrence J. Hak OriginalPaper Pages: 1172 - 1176
Determination of Temafloxacin, Sarafloxacin, and Difloxacin in Bulk Drug and Dosage Forms by High-Performance Liquid Chromatography John F. BauerLee Elrod, Jr.John E. Quick OriginalPaper Pages: 1177 - 1180
Physical State of Misoprostol in Hydroxypropyl Methylcellulose Films Tugrul T. KararliThomas E. NeedhamJeffrey Hurlbut OriginalPaper Pages: 1181 - 1185
Stabilization of Misoprostol with Hydroxypropyl Methylcellulose (HPMC) Against Degradation by Water Tugrul T. KararliThomas Catalano OriginalPaper Pages: 1186 - 1189
Release of Human Serum Albumin from Poly(lactide-co-glycolide) Microspheres Maninder S. HoraRajsharan K. RanaMichael E. Hudson OriginalPaper Pages: 1190 - 1194
A Flat Circular Hole Device for Zero-Order Release of Drugs: Characterization of the Moving Dissolution Boundary Dinesh S. MishraSamuel H. Yalkowsky Note Pages: 1195 - 1197
Scintigraphic Evaluation of the Ocular Disposition of 18F-Imirestat in Rabbits Ganesan VaidyanathanMichael JayR. K. Brazzell Note Pages: 1198 - 1200
Epidermal Differentiation and Permeability in Fetal Pig Skin Tamie Kurihara-BergstromWilliam R. GoodMarguerite Woodworth Note Pages: 1201 - 1204
Morphine Impurity with Opioid Activity Is Identified as 10α-Hydroxymorphine Hassan FarsamSteven EigerWolfgang Sadée Note Pages: 1205 - 1207
Effects of a Diluent on the Retarded–Release Property of Acrylate Methacrylate–Salicylic Acid Coacervates R. S. OkorM. A. Yahaya Note Pages: 1208 - 1209