In Vivo Characteristics of Cationic Liposomes as Delivery Vectors for Gene Therapy Sandrine A. L. AudouyLou F. M. H. de LeijGrietje Molema ReviewPaper Pages: 1599 - 1605
The Use of in Vitro Metabolic Stability for Rapid Selection of Compounds in Early Discovery Based on Their Expected Hepatic Extraction Ratios Yau Yi LauGopal KrishnaChin-Chung Lin OriginalPaper Pages: 1606 - 1610
Predicting Blood–Brain Barrier Partitioning of Organic Molecules Using Membrane–Interaction QSAR Analysis Manisha IyerRama MishraA. J. Hopfinger OriginalPaper Pages: 1611 - 1621
Quantitative Structure–Permeation Relationships for Solute Transport Across Silicone Membranes Sandrine GeinozSebastien ReyBernard Testa OriginalPaper Pages: 1622 - 1629
An Integrated Pharmacodynamic Analysis of Erythropoietin, Reticulocyte, and Hemoglobin Responses in Acute Anemia P. Veng-PedersonS. ChapelJ. A. Widness OriginalPaper Pages: 1630 - 1635
Hydraulic Flow and Vascular Clearance Influences on Intravitreal Drug Delivery Paul J. Missel OriginalPaper Pages: 1636 - 1647
Kinetic Analysis of Covalent Binding Between N-Acetyl-L-Cysteine and Albumin Through the Formation of Mixed Disulfides in Human and Rat Serum in Vitro Daisuke HaradaShinsaku NaitoMasaki Otagiri OriginalPaper Pages: 1648 - 1654
Evidence for Dissolution Rate-Limited Absorption of COL-3, a Matrix Metalloproteinase Inhibitor, Leading to the Irregular Absorption Profile in Rats After Oral Administration Jing LiHung HuynhEli Chan OriginalPaper Pages: 1655 - 1662
Hydrogen Bonding with Adsorbent During Storage Governs Drug Dissolution from Solid-Dispersion Granules Manish K. GuptaYin-Chao TsengRobin H. Bogner OriginalPaper Pages: 1663 - 1672
Transdermal Drug Delivery by Jet Injectors: Energetics of Jet Formation and Penetration Joy SchrammSamir Mitragotri OriginalPaper Pages: 1673 - 1679
Enhanced Permeability of Molecular Weight Markers and Poorly Bioavailable Compounds Across Caco-2 Cell Monolayers Using the Absorption Enhancer, Zonula Occludens Toxin Donna S. CoxSangeeta RajeNatalie D. Eddington OriginalPaper Pages: 1680 - 1688
Enhanced Permeability of the Antimicrobial Agent 2,5-Bis(4-Amidinophenyl)Furan Across Caco-2 Cell Monolayers Via Its Methylamidoxime Prodrug Lian ZhouKiho LeeJames E. Hall OriginalPaper Pages: 1689 - 1695
Transport of HIV-Protease Inhibitors Across 1α,25di-Hydroxy Vitamin D3-Treated Calu-3 Cell Monolayers: Modulation of P-Glycoprotein Activity Jignesh PatelDhananjay PalAshim K. Mitra OriginalPaper Pages: 1696 - 1703
Transepithelial Transport of Prodrugs of the HIV Protease Inhibitors Saquinavir, Indinavir, and Nelfinavir Across Caco-2 Cell Monolayers Marielle RouquayrolBérangère GaucherPierre Vierling OriginalPaper Pages: 1704 - 1712
Poly(d,l-Lactide-Co-Glycolide) Encapsulated Poly(Vinyl Alcohol) Hydrogel as a Drug Delivery System Tarun K. MandalLevon A. BostanianSharlene R. Chapman OriginalPaper Pages: 1713 - 1719
AlbugraninTM, a Recombinant Human Granulocyte Colony Stimulating Factor (G-CSF) Genetically Fused to Recombinant Human Albumin Induces Prolonged Myelopoietic Effects in Mice and Monkeys Wendy HalpernTodd A. RiccobeneKrzysztof J. Grzegorzewski OriginalPaper Pages: 1720 - 1729
Cellular Handling of a Dexamethasone-Anti-E-Selectin Immunoconjugate by Activated Endothelial Cells: Comparison with Free Dexamethasone Robbert J. KokMaaike EvertsGrietje Molema OriginalPaper Pages: 1730 - 1735
A Novel Hepatic-Targeting System for Therapeutic Cytokines That Delivers to the Hepatic Asialoglycoprotein Receptor, but Avoids Receptor-Mediated Endocytosis Haruya SatoYukio KatoYuichi Sugiyama OriginalPaper Pages: 1736 - 1744
Determination of Local Tissue Concentrations of Bupivacaine Released from Biodegradable Microspheres and the Effect of Vasoactive Compounds on Bupivacaine Tissue Clearance Studied by Microdialysis Sampling Sarah McDonaldAlexander A. FaibushevichCraig Lunte OriginalPaper Pages: 1745 - 1752
Complexation of VEGF with Bevacizumab Decreases VEGF Clearance in Rats Vanessa HseiGeralyn G. DeGuzmanJacques Gaudreault BriefCommunication Pages: 1753 - 1756
Augmented Expression of the Tight Junction Protein Occludin in Brain Endothelial Cell Line TR-BBB by Rat Angiopoietin-1 Expressed in Baculovirus-Infected Sf Plus Insect Cells Hisashi IizasaSun-Hye BaeEmi Nakashima BriefCommunication Pages: 1757 - 1760
Assuring Quality and Performance of Sustained and Controlled Release Parenterals: AAPS Workshop Report, Co-Sponsored by FDA and USP Diane J. BurgessAjaz S. HussainMei-Ling Chen Legacy Pages: 1761 - 1768