News from the National Institute of General Medical Sciences (NIGMS) Peter C. Preusch News Pages: 373 - 374
Subject-by-Formulation Interaction in Bioequivalence: Conceptual and Statistical Issues Walter W. HauckTerry HyslopRoger L. Williams OriginalPaper Pages: 375 - 380
Bioequivalence of Methylphenidate Immediate-Release Tablets Using a Replicated Study Design to Characterize Intrasubject Variability Marvin C. MeyerArthur B. StraughnVinod P. Shah OriginalPaper Pages: 381 - 384
Pharmacokinetics of a Hematoregulatory Peptide (SK&F 107647) in Healthy Male Volunteers and in Patients with Colorectal or Pancreatic Adenocarcinoma Not Amenable to Standard Therapy Parnian Zia-AmirhosseiniRobert Z. HarrisCharles B. Davis OriginalPaper Pages: 385 - 390
Stability of Human Serum Albumin During Bioprocessing: Denaturation and Aggregation During Processing of Albumin Paste Jen-Jen LinJeffrey D. MeyerMark C. Manning OriginalPaper Pages: 391 - 396
What is the True Solubility Advantage for Amorphous Pharmaceuticals? Bruno C. HancockMichael Parks OriginalPaper Pages: 397 - 404
Photomechanical Drug Delivery into Bacterial Biofilms Nikolaos S. SoukosSigmund S. SocranskyApostolos G. Doukas OriginalPaper Pages: 405 - 409
Allometric Pharmacokinetic Scaling: Towards the Prediction of Human Oral Pharmacokinetics Meihua Rose FengXiaochun LouAthiwat Hutchaleelaha OriginalPaper Pages: 410 - 418
Prediction of In Vivo Interaction Between Triazolam and Erythromycin Based on In Vitro Studies Using Human Liver Microsomes and Recombinant Human CYP3A4 Shin-ichi KanamitsuKiyomi ItoYuichi Sugiyama OriginalPaper Pages: 419 - 426
The Stereoselective Distribution of Halofantrine Enantiomers Within Human, Dog, and Rat Plasma Lipoproteins Dion R. BrocksManisha RamaswamyKishor M. Wasan OriginalPaper Pages: 427 - 431
Pharmacokinetic Study of the Hepatobiliary Transport of Indomethacin Hirokazu KouzukiHiroshi SuzukiYuichi Sugiyama OriginalPaper Pages: 432 - 438
Dissolution Testing as a Prognostic Tool for Oral Drug Absorption: Dissolution Behavior of Glibenclamide Raimar LöbenbergJohannes KrämerJennifer B. Dressman OriginalPaper Pages: 439 - 444
Effect of the Concurrent LHRH Antagonist Administration with a LHRH Superagonist in Rats Janusz W. KostanskiBhas A. DaniPatrick P. DeLuca OriginalPaper Pages: 445 - 450
Synthetic Glycopeptide-Based Delivery Systems for Systemic Gene Targeting to Hepatocytes Khursheed AnwerMark LoganAlain Rolland OriginalPaper Pages: 451 - 459
Formation of Multilayers in the Caco-2 Cell Culture Model: A Confocal Laser Scanning Microscopy Study Barbara Rothen-RutishauserAnnette BraunHeidi Wunderli-Allenspach OriginalPaper Pages: 460 - 465
Transdermal Extraction of Analytes Using Low-Frequency Ultrasound Samir MitragotriMatthew ColemanRobert Langer OriginalPaper Pages: 466 - 470
Visualization and Analysis of Electroosmotic Flow in Hairless Mouse Skin Bradley D. BathHenry S. WhiteErik R. Scott OriginalPaper Pages: 471 - 475
Iontophoresis-Enhanced Absorptive Flux of Polar Molecules Across Intestinal Tissue In Vitro Maurice LeonardElizabeth CreedAlan W. Baird BriefCommunication Pages: 476 - 478
Role of P-Glycoprotein in Ocular Clearance of Rhodamine 123 in Rabbits Tetsu KajikawaHiromu K. MishimaMikihisa Takano BriefCommunication Pages: 479 - 481
In Vivo Absorption Properties of Orally Administered Recombinant Human Interleukin-11 Chih-Ming Leo TsengLeo AlbertSoo-Peang Khor BriefCommunication Pages: 482 - 485
Solid State NMR Investigations on Nanosized Carrier Systems Christian MayerGerold Lukowski BriefCommunication Pages: 486 - 489
Effect of the Storage Conditions on the Tensile Strength of Tablets in Relation to the Enthalpy Relaxation of the Binder F. KiekensR. ZelkoJ. P. Remon OriginalPaper Pages: 490 - 493