1. News from the National Institute of General Medical Sciences (NIGMS)

   • Rochelle M. Long

   News Pages: 1647 - 1648

2. Estimating the Critical Molecular Mobility Temperature (TK) of Amorphous Pharmaceuticals

   • Bruno C. Hancock
   • Karen Christensen
   • Sheri L. Shamblin

   Letter to the Editor Pages: 1649 - 1651

3. Antibodies as Carrier Proteins

   • Bruce N. Rehlaender
   • Moo J. Cho

   ReviewPaper Pages: 1652 - 1656

4. BBB Transport and P-glycoprotein Functionality Using MDR1A (-/-) and Wild-Type Mice. Total Brain Versus Microdialysis Concentration Profiles of Rhodamine-123

   • Elizabeth C. M. de Lange
   • Gertjan de Bock
   • Douwe D. Breimer

   OriginalPaper Pages: 1657 - 1665

5. In Vitro and In Situ Absorption of SDZ-RAD Using a Human Intestinal Cell Line (Caco-2) and a Single Pass Perfusion Model in Rats: Comparison with Rapamycin

   • Andrew Crowe
   • Michel Lemaire

   OriginalPaper Pages: 1666 - 1672

6. Methodological Aspects of the Use of a Calibrator in In Vivo Microdialysis–Further Development of the Retrodialysis Method

   • M. René Bouw
   • Margareta Hammarlund-Udenaes

   OriginalPaper Pages: 1673 - 1679

7. Effect of Ultrasound Application on Skin Metabolism of Prednisolone 21-Acetate

   • Tomohiro Hikima
   • Yoshiaki Hirai
   • Kakuji Tojo

   OriginalPaper Pages: 1680 - 1683

8. Biotransformation of Estradiol in the Human Keratinocyte Cell Line HaCaT: Metabolism Kinetics and the Inhibitory Effect of Ethanol

   • Ralf Altenburger
   • Thomas Kissel

   OriginalPaper Pages: 1684 - 1689

9. Scavenging of the One-Electron Reduction Product from Nisoldipine with Relevant Thiols: Electrochemical and EPR Spectroscopic Evidences

   • Luis J. Núñez-Vergara
   • G. Díaz-Araya
   • J. A. Squella

   OriginalPaper Pages: 1690 - 1695

10. Co-Administration of a Water-Soluble Polymer Increases the Usefulness of Cyclodextrins in Solid Oral Dosage Forms

    • Jouko Savolainen
    • Kristiina Järvinen
    • Tomi Järvinen

    OriginalPaper Pages: 1696 - 1701

11. Isothermal and Nonisothermal Decomposition of Thymopentin and Its Analogs in Aqueous Solution

    • Mu-Lan Lee
    • Salomon Stavchansky

    OriginalPaper Pages: 1702 - 1707

12. Microencapsulation of Hepatitis B Core Antigen for Vaccine Preparation

    • Takahiro Uchida
    • Kouichi Shiosaki
    • Kenji Matsuyama

    OriginalPaper Pages: 1708 - 1713

13. Quantitative Determination of the Extent of Neutralization of Carboxylic Acid Functionality in Carbopol® 974P NF by Diffuse Reflectance Fourier Transform Infrared Spectrometry Using Kubelka-Munk Function

    • Rong-Hwei Juang
    • David E. Storey

    OriginalPaper Pages: 1714 - 1720

14. Visualization of PEO-PBLA-Pyrene Polymeric Micelles by Atomic Force Microscopy

    • Jiahorng Liaw
    • Takao Aoyagi
    • Teruo Okano

    OriginalPaper Pages: 1721 - 1726

15. Can the Organization of a Binary Mix Be Predicted from the Surface Energy, Cohesion Parameter and Particle Size of Its Components?

    • J. Barra
    • F. Lescure
    • E. Doelker

    OriginalPaper Pages: 1727 - 1736

16. Enhanced Encapsulation of Amphotericin B into Liposomes by Complex Formation with Polyethylene Glycol Derivatives

    • Kunikazu Moribe
    • Eitaro Tanaka
    • Motoharu Iwatsuru

    OriginalPaper Pages: 1737 - 1742

17. Ultrasonic Nebulization of Cationic Lipid-Based Gene Delivery Systems for Airway Administration

    • Ravi Pillai
    • Karel Petrak
    • Alain Rolland

    OriginalPaper Pages: 1743 - 1747

18. A New Powder Design Method to Improve Inhalation Efficiency of Pranlukast Hydrate Dry Powder Aerosols by Surface Modification with Hydroxypropylmethylcellulose Phthalate Nanospheres

    • Yoshiaki Kawashima
    • Takanori Serigano
    • Hirofumi Takeuchi

    OriginalPaper Pages: 1748 - 1752

19. Surface-modified Antiasthmatic Dry Powder Aerosols Inhaled Intratracheally Reduce the Pharmacologically Effective Dose

    • Yoshiaki Kawashima
    • Takanori Serigano
    • Hirofumi Takeuchi

    OriginalPaper Pages: 1753 - 1759

20. Antiproliferative and Cytotoxic Effects of Geldanamycin, Cytochalasin E, Suramin and Thiacetazone in Human Prostate Xenograft Tumor Histocultures

    • Yuebo Gan
    • Jessie L.-S. Au
    • M. Guillaume Wientjes

    OriginalPaper Pages: 1760 - 1766

21. Effects of Cholecystokinin Octapeptide on a Pancreatic Acinar Carcinoma in the Rat

    • Amor Hajri
    • Christiane Damgé

    OriginalPaper Pages: 1767 - 1774

22. Altered Tissue Distribution and Elimination of Amikacin Encapsulated in Unilamellar, Low-Clearance Liposomes (MiKasome^®)

    • Robert M. Fielding
    • Ramilla O. Lewis
    • Lotus Moon-McDermott

    OriginalPaper Pages: 1775 - 1781

23. Estimation of Oral Bioavailability of a Long Half-Life Drug in Healthy Subjects

    • Amarnath Sharma
    • Peter H. Slugg
    • William J. Jusko

    OriginalPaper Pages: 1782 - 1786

24. The Relative Bioavailability and In Vivo-In Vitro Correlations for Four Marketed Carbamazepine Tablets

    • Marvin C. Meyer
    • Arthur B. Straughn
    • Larry J. Lesko

    OriginalPaper Pages: 1787 - 1791

25. Linear Correlation of the Fraction of Oral Dose Absorbed of 64 Drugs Between Humans and Rats

    • Win L. Chiou
    • Abhijit Barve

    BriefCommunication Pages: 1792 - 1795

26. Considerations in the Attainment of Steady State: Aggregate vs. Individual Assessment

    • Walter W. Hauck
    • Thomas N. Tozer
    • Frédéric Y. Bois

    BriefCommunication Pages: 1796 - 1798

27. Stability of UC-781, in Intestinal Mucosal Homogenates of the Rat, Rabbit, and Pig

    • Guy Van den Mooter
    • Geert Stas
    • Patrick Augustijns

    BriefCommunication Pages: 1799 - 1802

28. BOOK REVIEWS

    BookReview Pages: 1803 - 1806