1. Pharmacokinetic–Pharmacodynamic Modeling of the Hydroxy Lerisetron Metabolite L6-OH in Rats: An Integrated Parent–Metabolite Model

   • Fátima Ortega
   • Antonio Quintana
   • Rosario Calvo

   Research Paper 20 September 2005 Pages: 1769 - 1782

   

2. Modeling of Human Corticosteroid Binding Globulin. Use of Structure–Activity Relations in Soft Steroid Binding to Refine the Structure

   • Roy J. Little
   • C. G. Rodríguez

   Research Paper 16 August 2005 Pages: 1783 - 1792

   

3. Membrane Binding Proteins are the Major Determinants for the Hepatocellular Transmembrane Flux of Long-Chain Fatty Acids Bound to Albumin

   • G. Rajaraman
   • M. S. Roberts
   • F. J. Burczynski

   Research Paper 16 August 2005 Pages: 1793 - 1804

   

4. Comparison of (−)-Epigallocatechin-3-Gallate Elicited Liver and Small Intestine Gene Expression Profiles Between C57BL/6J Mice and C57BL/6J/Nrf2 (−/−) Mice

   • Guoxiang Shen
   • Changjiang Xu
   • A.-N. Tony Kong

   Research Paper 16 August 2005 Pages: 1805 - 1820

   

5. Blood Compatibility of Cetyl Alcohol/Polysorbate-Based Nanoparticles

   • J. M. Koziara
   • J. J. Oh
   • R. J. Mumper

   Research Paper 26 August 2005 Pages: 1821 - 1828

   

6. Modification of the P-Glycoprotein Dependent Pharmacokinetics of Digoxin in Rats by Human Recombinant Interferon-α

   • Makrem Ben Reguiga
   • Laurence Bonhomme-Faivre
   • Robert Farinotti

   Research Paper 16 August 2005 Pages: 1829 - 1836

   

7. Human Multidrug Resistance Associated Protein 4 Confers Resistance to Camptothecins

   • Quan Tian
   • Jing Zhang
   • Shufeng Zhou

   Research Paper 01 September 2005 Pages: 1837 - 1853

   

8. Region-Dependent Role of the Mucous/Glycocalyx Layers in Insulin Permeation Across Rat Small Intestinal Membrane

   • Yoshinobu Aoki
   • Mariko Morishita
   • Kozo Takayama

   Research Paper 29 July 2005 Pages: 1854 - 1862

   

9. Bile Increases Intestinal Lymphatic Drug Transport in the Fasted Rat

   • Natalie L. Trevaskis
   • Christopher J. H. Porter
   • William N. Charman

   Research Paper 16 August 2005 Pages: 1863 - 1870

   

10. The Effect of Formulation Variables and Breathing Patterns on the Site of Nasal Deposition in an Anatomically Correct Model

    • Yang Guo
    • Beth Laube
    • Richard Dalby

    Research Paper 16 August 2005 Pages: 1871 - 1878

    

11. Insulin Containing Nanocomplexes Formed by Self-Assembly from Biodegradable Amine-Modified Poly(Vinyl Alcohol)-Graft-Poly(l-Lactide): Bioavailability and Nasal Tolerability in Rats

    • Michael Simon
    • Matthias Wittmar
    • Thomas Linn

    Research Paper 26 August 2005 Pages: 1879 - 1886

    

12. Solid Lipid Nanoparticles (SLN) and Oil-Loaded SLN Studied by Spectrofluorometry and Raman Spectroscopy

    • Katja Jores
    • Annekathrin Haberland
    • Wolfgang Mehnert

    Research Paper 01 September 2005 Pages: 1887 - 1897

    

13. Tissue Distribution of Indinavir Administered as Solid Lipid Nanocapsule Formulation in mdr1a (+/+) and mdr1a (−/−) CF-1 Mice

    • Manuela Pereira de Oliveira
    • Emmanuel Garcion
    • Jean-Christophe Olivier

    Research Paper 21 October 2005 Pages: 1898 - 1905

    

14. Immunoliposomes Directed Toward VCAM-1 Interact Specifically with Activated Endothelial Cells—A Potential Tool for Specific Drug Delivery

    • Manuela Voinea
    • Ileana Manduteanu
    • Maya Simionescu

    Research Paper 13 August 2005 Pages: 1906 - 1917

    

15. Investigation of Iminosulfuranes as Novel Transdermal Penetration Enhancers: Enhancement Activity and Cytotoxicity

    • Yifan Song
    • Chunhong Xiao
    • Bozena Michniak

    Research Paper 16 August 2005 Pages: 1918 - 1925

    

16. Differences in Surfactant Lipids Collected from Pleural and Pulmonary Lining Fluids

    • Paul C. Mills
    • Yi Chen
    • Brian A. Hills

    Research Paper 19 August 2005 Pages: 1926 - 1930

17. Displacement of Adsorbed Insulin by Tween 80 Monitored Using Total Internal Reflection Fluorescence and Ellipsometry

    • S. H. Mollmann
    • U. Elofsson
    • S. Frokjaer

    Research Paper 16 August 2005 Pages: 1931 - 1941

    

18. Quantification of Crystallinity in Substantially Amorphous Materials by Synchrotron X-ray Powder Diffractometry

    • Cletus Nunes
    • Arumugam Mahendrasingam
    • Raj Suryanarayanan

    Research Paper 31 August 2005 Pages: 1942 - 1953

    

19. Alteration of the Pharmacokinetics of COL-3, a Matrix Metalloproteinase Inhibitor, Due to Acute Gastrointestinal Toxicity of Doxorubicin

    • Jing Li
    • Shufeng Zhou
    • Eli Chan

    Research Paper 13 August 2005 Pages: 1954 - 1963

    

20. Study of Crystal Packing on the Solid-State Reactivity of Indomethacin with Density Functional Theory

    • Tonglei Li
    • Shaoxin Feng

    Research Paper 16 August 2005 Pages: 1964 - 1969

    

21. Bitterness Suppression with Zinc Sulfate and Na-Cyclamate: A Model of Combined Peripheral and Central Neural Approaches to Flavor Modification

    • Russell S. J. Keast
    • Paul A. S. Breslin

    Research Paper 26 August 2005 Pages: 1970 - 1977

    

22. Influence of the Active Pharmaceutical Ingredient Concentration on the Physical State of Mannitol—Implications in Freeze-Drying

    • Xiangmin Liao
    • Rajesh Krishnamurthy
    • Raj Suryanarayanan

    Research Paper 31 August 2005 Pages: 1978 - 1985

    

23. AAPS Update

    OriginalPaper 17 October 2005 Pages: 1986 - 1987