Residual Solvent Testing: A Review of Gas-Chromatographic and Alternative Techniques Clayton B'Hymer ReviewPaper Pages: 337 - 344
Intradermal Injection of Transforming Growth Factor-β1 Gene Enhances Wound Healing in Genetically Diabetic Mice Sophie ChesnoyPui-Yan LeeLeaf Huang OriginalPaper Pages: 345 - 350
Simultaneous Modulation of Multidrug Resistance and Antiapoptotic Cellular Defense by MDR1 and BCL-2 Targeted Antisense Oligonucleotides Enhances the Anticancer Efficacy of Doxorubicin Refika I. PakunluThomas J. CookTamara Minko OriginalPaper Pages: 351 - 359
Binding and Cytotoxicity of HPMA Copolymer Conjugates to Lymphocytes Mediated by Receptor-Binding Epitopes Aijun TangPavla KopečkováJindřich Kopeček OriginalPaper Pages: 360 - 367
Disposition Kinetics of α-Tocopherol in Apolipoprotein B Knockout Mice Koichi YokogawaYuichiro ShimaKen-ichi Miyamoto OriginalPaper Pages: 368 - 372
An Improved Cell Culture Model Based on 2/4/A1 Cell Monolayers for Studies of Intestinal Drug Transport: Characterization of Transport Routes Staffan TavelinJan TaipalensuuPer Artursson OriginalPaper Pages: 373 - 381
Limits for the Scaled Average Bioequivalence of Highly Variable Drugs and Drug Products Laszlo TothfalusiLaszlo Endrenyi OriginalPaper Pages: 382 - 389
Computation of Log BB Values for Compounds Transported Through Carrier-Mediated Mechanisms Using in Vitro Permeability Data from Brain Microvessel Endothelial Cell (BMEC) Monolayers Helen H. UsanskyPatrick J. Sinko OriginalPaper Pages: 390 - 396
Prediction of the Oral Absorption of Low-Permeability Drugs Using Small Intestine-Like 2/4/A1 Cell Monolayers Staffan TavelinJan TaipalensuuPer Artursson OriginalPaper Pages: 397 - 405
The Mean Dissolution Time Depends on the Dose/Solubility Ratio Eleni RinakiAristides DokoumetzidisPanos Macheras OriginalPaper Pages: 406 - 408
Direct Evidence That Polysorbate-80-Coated Poly(Butylcyanoacrylate) Nanoparticles Deliver Drugs to the CNS via Specific Mechanisms Requiring Prior Binding of Drug to the Nanoparticles Jörg KreuterPeter RamgeDavid J. Begley OriginalPaper Pages: 409 - 416
Antitumor Activity of Folate Receptor-Targeted Liposomal Doxorubicin in a KB Oral Carcinoma Murine Xenograft Model Xing Q. PanHuaqing WangRobert J. Lee OriginalPaper Pages: 417 - 422
Liposome-Mediated Targeting of Enzymes to Cancer Cells for Site-Specific Activation of Prodrugs: Comparison with the Corresponding Antibody-Enzyme Conjugate María José FonsecaJoycelyn C. JagtenbergGert Storm OriginalPaper Pages: 423 - 428
Effect of Colonic Lactulose Availability on the Timing of Drug Release Onset in Vivo from a Unique Colon-Specific Drug Delivery System (CODES™) Libo YangShunsuke WatanabeJoseph A. Fix OriginalPaper Pages: 429 - 434
Monitoring the in Vivo Delivery of Proteins from Carbomer Hydrogels by X-Ray Fluorescence Donald S. MacLean-McDavittJ. David RobertsonMichael Jay OriginalPaper Pages: 435 - 441
In Vitro Evaluation of Nebulization Properties, Antimicrobial Activity, and Regional Airway Surface Liquid Concentration of Liposomal Polymyxin B Sulfate Tejas R. DesaiGregory J. TyrrellWarren H. Finlay OriginalPaper Pages: 442 - 447
Disposition and Oral Bioavailability in Rats of an Antiviral and Antitumor Amino Acid Phosphoramidate Prodrug of AZT-Monophosphate Heng SongRachel JohnsCheryl L. Zimmerman OriginalPaper Pages: 448 - 451
Preparation and in Vitro/in Vivo Evaluation of Insulin-Loaded Poly(Acryloyl-Hydroxyethyl Starch)-PLGA Composite Microspheres Ge JiangWei QiuPatrick P. DeLuca OriginalPaper Pages: 452 - 459
Evaluation of the in Vivo Disintegration of Solid Dosage Forms of a Bile Acid Sequestrant in Dogs Using γ-Scintigraphy and Correlation to in Vitro Disintegration Munir A. HussainRong-Kun ChangGeorge A. Digenis OriginalPaper Pages: 460 - 464
Self-Micellization of Gemfibrozil 1-O-β Acyl Glucuronide in Aqueous Solution David M. ShacklefordRichard J. PrankerdWilliam N. Charman OriginalPaper Pages: 465 - 470
Thermodynamics of Solutions I: Benzoic Acid and Acetylsalicylic Acid as Models for Drug Substances and the Prediction of Solubility German L. PerlovichAnnette Bauer-Brandl OriginalPaper Pages: 471 - 478
Characterization of Crystalline Drug Nanoparticles Using Atomic Force Microscopy and Complementary Techniques Huaiqiu Galen ShiLeon FarberMichael J. Kaufman OriginalPaper Pages: 479 - 484
Enhanced Aqueous Dissolution of a Poorly Water Soluble Drug by Novel Particle Engineering Technology: Spray-Freezing into Liquid with Atmospheric Freeze-Drying True L. RogersAndrew C. NelsenRobert O. Williams III OriginalPaper Pages: 485 - 493
In-Situ Near-Infrared Spectroscopy Monitoring of the Lyophilization Process Mikael BrüllsStaffan FolestadAnders Rasmuson OriginalPaper Pages: 494 - 499
Characterization of the Thermal Properties of Powder Particles Using Microthermal Analysis John. R. MurphyChristopher S. AndrewsDuncan Q. M. Craig OriginalPaper Pages: 500 - 507
Characterization of Particle-Interactions by Atomic Force Microscopy: Effect of Contact Area Jennifer C. HootonCaroline S. GermanPhilip M. Williams OriginalPaper Pages: 508 - 514
Hollow Filler–Binders as Excipients for Direct Compaction Gerad K. BolhuisAnko C. EissensHenderik W. Frijlink OriginalPaper Pages: 515 - 518
