Editorial: A Systems Approach to Drug Development and to Drug Therapy Walter Wolf Editorial Introduction Pages: 1 - 2
Messenger RNA Expression of Transporter and Ion Channel Genes in Undifferentiated and Differentiated Caco-2 Cells Compared to Human Intestines Pascale AnderleVera RakhmanovaWolfgang Sadée OriginalPaper Pages: 3 - 15
Novel Ethanol-in-Fluorocarbon Microemulsions for Topical Genetic Immunization Zhengrong CuiWilliam FountainRussell J. Mumper OriginalPaper Pages: 16 - 23
Enhanced Oral Bioavailability of Paclitaxel by Coadministration of the P-Glycoprotein Inhibitor KR30031 Jong Soo WooChang Hyun LeeSung-Joo Hwang OriginalPaper Pages: 24 - 30
Impact of Mrp2 on the Biliary Excretion and Intestinal Absorption of Furosemide, Probenecid, and Methotrexate Using Eisai Hyperbilirubinemic Rats Cuiping ChenDennis ScottXingrong Liu OriginalPaper Pages: 31 - 37
Kinetic Analysis of P-Glycoprotein-Mediated Transport by Using Normal Human Placental Brush-Border Membrane Vesicles Fumihiko UshigomeNoriko KoyabuYasufumi Sawada OriginalPaper Pages: 38 - 44
Enhanced Drug-Induced Apoptosis Associated with P-Glycoprotein Overexpression Is Specific to Antimicrotubule Agents Dong LiSeong H. JangJessie L.-S. Au OriginalPaper Pages: 45 - 50
Influence of Spacer Length on Interaction of Mannosylated Liposomes with Human Phagocytic Cells Andreas EngelSwapan Kumar ChatterjeePeter Nuhn OriginalPaper Pages: 51 - 57
Kinetic Analysis of Saturable Myocardial Uptake of Idarubicin in Rat Heart: Effect of Doxorubicin and Hypothermia Wonku KangMichael Weiss OriginalPaper Pages: 58 - 63
In Vitro Cellular Handling and in Vivo Targeting of E-Selectin-Directed Immunoconjugates and Immunoliposomes Used for Drug Delivery to Inflamed Endothelium Maaike EvertsGerben A. KoningGrietje Molema OriginalPaper Pages: 64 - 72
Structural Studies of EDTA-Induced Fibrillation of Salmon Calcitonin Stefan SeyferthGeoffrey Lee OriginalPaper Pages: 73 - 80
Microsomal Cytochrome P450 Levels and Activities of Isolated Rat Livers Perfused with Albumin Ragini VuppugallaRakhi B. ShahReza Mehvar OriginalPaper Pages: 81 - 88
Hepatobiliary Transport of a Nonpeptidic Endothelin Antagonist, (+)-(5S,6R, 7R)-2-Butyl-7-[2((2S)-2-Carboxypropyl)-4-Methoxyphenyl]-5-(3,4-Methylenedioxyphenyl) Cyclopentenol[1,2-b]Pyridine-6-Carboxylic Acid: Uptake by Isolated Rat Hepatocytes and Canalicular Membrane Vesicles Naoko KobayashiTakeshi TaniToshio Yasumori OriginalPaper Pages: 89 - 95
Computer Simulation of Convective and Diffusive Transport of Controlled-Release Drugs in the Vitreous Humor Matthew S. StayJing XuVictor H. Barocas OriginalPaper Pages: 96 - 102
Pharmacokinetics and Metabolism of Transdermal Oxybutynin: In Vitro and in Vivo Performance of a Novel Delivery System R. Howard ZobristDanyi QuanSteven W. Sanders OriginalPaper Pages: 103 - 109
Microfabricated Porous Silicon Particles Enhance Paracellular Delivery of Insulin Across Intestinal Caco-2 Cell Monolayers Amy B. ForakerRob J. WalczakPeter W. Swaan OriginalPaper Pages: 110 - 116
Direct Formation of Nanospheres from Amphiphilic β-Cyclodextrin Inclusion Complexes Erem MemişoğluAmélie BochotA. Atilla Hincal OriginalPaper Pages: 117 - 125
Modifications in Lipoprotein Surface Charge Alter Cyclosporine A Association with Low-Density Lipoproteins Kishor M. WasanOlena Sivak OriginalPaper Pages: 126 - 129
Oral-Antigen Delivery via a Water-in-Oil Emulsion System Modulates the Balance of the Th1/Th2 Type Response in Oral Tolerance Kazuyoshi MasudaKazutoshi HorieKoichiro Hirano OriginalPaper Pages: 130 - 134
Identification of Phase Separation in Solid Dispersions of Itraconazole and Eudragit® E100 Using Microthermal Analysis Karel SixJohn MurphyGuy Van den Mooter OriginalPaper Pages: 135 - 138
Reviewers for Pharmaceutical Research for the Period of November 1, 2001 and October 31, 2002 Legacy Pages: 141 - 142
